Pneumococcal antibody concentrations and carriage of pneumococci more than 3 years after infant immunization with a pneumococcal conjugate vaccine. [PDF]
BACKGROUND: A 9-valent pneumococcal conjugate vaccine (PCV-9), given in a 3-dose schedule, protected Gambian children against pneumococcal disease and reduced nasopharyngeal carriage of pneumococci of vaccine serotypes.
Greenwood, Brian M +31 more
core +1 more source
Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping. [PDF]
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Gurung, M +40 more
core +2 more sources
7-Valent pneumococcal conjugate vaccination in England and Wales: is it still beneficial despite high levels of serotype replacement? [PDF]
BACKGROUND: The UK introduced the 7-valent pneumococcal conjugate vaccine (PCV7) into the national vaccination program in September 2006. Previous modelling assumed that the likely impact of PCV7 on invasive pneumococcal disease (IPD) would be similar to
Nigel Gay +31 more
core +1 more source
BACKGROUND Pneumococcal conjugate vaccines (PCVs) have reduced vaccine-type (VT) invasive pneumococcal disease (IPD) in older adults through direct and indirect effects. However, non-vaccine-type serotypes have emerged.
on behalf of the Israeli Adult Pneumococcal Invasive Disease (IAIPD) group
doaj +1 more source
Surveillance of invasive pneumococcal disease in 30 EU countries: Towards a European system?
In this era of new pneumococcal conjugate vaccines (PCV), we described and compared surveillance of invasive pneumococcal disease (IPD) and PCV policies in 30 European countries to provide guidance for Europe-wide surveillance.
Perrocheau, Anne +31 more
core +1 more source
Pneumococcal Disease in High-Risk Adults in Lebanon: Expert Opinion
Pneumococcal disease affects people across all ages but is more prevalent in young children and the elderly. Despite the availability of the pneumococcal vaccine for adults, the disease burden and mortality associated with it remains a challenge.
Abdulrahman Bizri +9 more
doaj +1 more source
Continued control of pneumococcal disease in the UK - the impact of vaccination
Streptococcus pneumoniae, also known as the pneumococcus, is an important cause of morbidity and mortality in the developed and developing world. Pneumococcal conjugate vaccines were first introduced for routine use in the USA in 2000, although the seven-
Gladstone, R.A. +11 more
core +1 more source
The remaining challenges of pneumococcal disease in adults [PDF]
Pneumococcal disease can be divided into invasive disease, i.e. when bacteria are detected in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs more frequently in younger children and older adults.
E. Ludwig +4 more
doaj
Regulation of naturally acquired mucosal immunity to Streptococcus pneumoniae in healthy Malawian adults and children. [PDF]
Worldwide, invasive pneumococcal disease caused by Streptococcus pneumoniae is most common in young children. In adults, disease rates decline following intermittent colonization and the acquisition of naturally acquired immunity.
Sarah J Glennie +5 more
doaj +1 more source
Few studies on adult pneumococcal septic arthritis are sufficiently large enough to assess both epidemiological trends following routine pneumococcal immunization and clinical disease. With major shifts in serotypes causing invasive pneumococcal disease (
Catherine Hyams +7 more
doaj +1 more source

