Results 1 to 10 of about 3,169,634 (297)

Pathogenesis of pneumococcal infection [PDF]

open access: bronzeJournal of Medical Microbiology, 2000
The pathogenesis of pneumococcal infection is a complex interplay between pneumococcal virulence determinants and the host immune response. Molecular studies have considerably advanced our knowledge and understanding of the precise structures and functions of the different determinants and their pathogenic roles. This review describes the mechanisms by
Stephen H. Gillespie   +1 more
openalex   +4 more sources

Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]

open access: yesPLoS ONE, 2011
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono   +4 more
doaj   +2 more sources

New Vaccines for the Prevention of Pneumococcal Infections

open access: diamondEmerging Infectious Diseases, 1996
Streptococcus pneumoniae is a major cause of acute otitis media, pneumonia, bacteremia, and meningitis. Because in recent years antibiotic-resistant pneumococcal strains have been emerging throughout the world, vaccination against pneumococcal infections
Helena Käyhty, Juhani Eskola
doaj   +2 more sources

THE CHEMOSEROTHERAPY OF EXPERIMENTAL PNEUMOCOCCAL INFECTION [PDF]

open access: bronzeJournal of Experimental Medicine, 1915
1. A single small dose of ethylhydrocuprein (optochin base), which by itself has practically no protective effect against experimental pneumococcal infection in mice, is capable of increasing the threshold value of the type homologous antipneumococcus serum at least fifty times. 2. This effect is proportionately many times greater than a
H. F. Moore
openalex   +4 more sources

Visualizing Pneumococcal Infections in the Lungs of Live Mice Using Bioluminescent Streptococcus pneumoniae Transformed with a Novel Gram-Positive lux Transposon [PDF]

open access: greenInfection and Immunity, 2001
Animal studies with Streptococcus pneumoniae have provided valuable models for drug development. In order to monitor long-term pneumococcal infections noninvasively in living mice, a novel gram-positive lux transposon cassette, Tn4001 luxABCDE Kmr, that ...
Kevin P. Francis   +9 more
openalex   +2 more sources

Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales [PDF]

open access: yes, 2012
England and Wales recently replaced the 7-valent pneumococcal conjugate vaccine (PCV7) with its 13-valent equivalent (PCV13), partly based on projections from mathematical models of the long-term impact of such a switch compared to ceasing pneumococcal ...
A Melegaro   +21 more
core   +17 more sources

The continuing problem of pneumococcal infection [PDF]

open access: bronzeJournal of Antimicrobial Chemotherapy, 1988
A.J. Davies, Dinakantha S. Kumaratne
openalex   +4 more sources

Association of Nonpharmaceutical Interventions During the COVID-19 Pandemic With Invasive Pneumococcal Disease, Pneumococcal Carriage, and Respiratory Viral Infections Among Children in France

open access: yesJAMA Network Open, 2022
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak   +18 more
semanticscholar   +1 more source

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