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Acute organ injury and long-term sequelae of severe pneumococcal infections. [PDF]
Streptococcus pneumoniae ( Spn ) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis.
Kruckow KL+3 more
europepmc +2 more sources
The Role of NLRP3 Inflammasome in Pneumococcal Infections. [PDF]
Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli.
Surabhi S+3 more
europepmc +2 more sources
Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono+4 more
doaj +2 more sources
New Vaccines for the Prevention of Pneumococcal Infections
Streptococcus pneumoniae is a major cause of acute otitis media, pneumonia, bacteremia, and meningitis. Because in recent years antibiotic-resistant pneumococcal strains have been emerging throughout the world, vaccination against pneumococcal infections
Helena Käyhty, Juhani Eskola
doaj +2 more sources
Incidence of Confirmed Influenza and Pneumococcal Infections and Vaccine Uptake Among Virologically Suppressed People Living with HIV [PDF]
Background/Objectives: Influenza and Streptococcus pneumoniae infections are common vaccine-preventable diseases to which people living with HIV (PLWH) may be more susceptible.
Edith Wolder Ejlersen+10 more
doaj +2 more sources
Pneumococcal Infection and Vaccination-Related Knowledge, Attitudes and Practices Among Saudi Residents [PDF]
Background and aims: Pneumococcal infections, primarily caused by Streptococcus pneumoniae, pose significant global public health challenges, particularly in vulnerable populations. In Saudi Arabia, the introduction of pneumococcal vaccination has been a
Wed S. Althobaiti+8 more
doaj +2 more sources
Pneumococcal carriage in sub-Saharan Africa--a systematic review. [PDF]
BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV)
A Fenoll+91 more
core +18 more sources
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak+18 more
semanticscholar +1 more source
Adult pneumococcal vaccination – new opportunities
Pneumococcal infections (Streptococcus pneumoniae) remain a significant epidemiological problem globally. Although an invasive pneumo-coccal disease (IPD), which includes meningitis, sepsis and pneumonia with bacteremia, is the most severe form of ...
ERNEST KUCHAR+13 more
doaj +1 more source
Biofilm-associated infections are of great concern because they are associated with antibiotic resistance and immune evasion. Co-colonization by Staphylococcus aureus and Streptococcus pneumoniae is possible and a threat in clinical practice.
Julio Sempere+7 more
doaj +1 more source