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The Role of NLRP3 Inflammasome in Pneumococcal Infections. [PDF]

open access: yesFront Immunol, 2020
Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli.
Surabhi S   +3 more
europepmc   +2 more sources

Pneumococcal infections and homelessness. [PDF]

open access: yesJ Prev Med Hyg, 2021
Objectif. To assess the prevalence of pneumococcal nasopharyngeal carriage, the role of potential risk factors, and vaccination against invasive pneumococcal diseases (IPD) among sheltered homeless persons (HP) in Marseille, France. Methods. In 2015 2018, we enrolled 571 sheltered homeless males and 54 non-homeless controls.
Ly TDA   +4 more
europepmc   +3 more sources

Pathogenesis of pneumococcal infection [PDF]

open access: bronzeJournal of Medical Microbiology, 2000
The pathogenesis of pneumococcal infection is a complex interplay between pneumococcal virulence determinants and the host immune response. Molecular studies have considerably advanced our knowledge and understanding of the precise structures and functions of the different determinants and their pathogenic roles. This review describes the mechanisms by
Stephen H. Gillespie   +1 more
openalex   +4 more sources

Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]

open access: yesPLoS ONE, 2011
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono   +4 more
doaj   +2 more sources

The prevention of pneumococcal infections. [PDF]

open access: yesClin Exp Vaccine Res, 2016
Streptococcus pneumoniae causes considerable number of diseases like pneumonia, bacteremia or sepsis, meningitis, otitis media, sinusitis, peritonitis, endocarditis, osteomyelitis, septic arthritis, and soft tissue infection [1,2,3]. According to the Korean statistics of death, 12,021 people died of pneumonia during the year 2014, mortality is 23.7 per
Chang MS, Woo JH.
europepmc   +4 more sources

Prevention of pneumococcal infections during mass gathering. [PDF]

open access: yesHum Vaccin Immunother, 2016
The interest in mass gathering and its implications has been increasing due to globalization and international travel. The potential occurrence of infectious disease outbreaks during mass gathering is most feared.
Al-Tawfiq JA, Memish ZA.
europepmc   +2 more sources

THE CHEMOSEROTHERAPY OF EXPERIMENTAL PNEUMOCOCCAL INFECTION [PDF]

open access: bronzeJournal of Experimental Medicine, 1915
1. A single small dose of ethylhydrocuprein (optochin base), which by itself has practically no protective effect against experimental pneumococcal infection in mice, is capable of increasing the threshold value of the type homologous antipneumococcus serum at least fifty times. 2. This effect is proportionately many times greater than a
H. F. Moore
openalex   +4 more sources

New Vaccines for the Prevention of Pneumococcal Infections

open access: diamondEmerging Infectious Diseases, 1996
Streptococcus pneumoniae is a major cause of acute otitis media, pneumonia, bacteremia, and meningitis. Because in recent years antibiotic-resistant pneumococcal strains have been emerging throughout the world, vaccination against pneumococcal infections
Helena Käyhty, Juhani Eskola
doaj   +2 more sources

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