Results 1 to 10 of about 3,296,751 (334)

Acute organ injury and long-term sequelae of severe pneumococcal infections. [PDF]

Pneumonia (Nathan), 2023
Streptococcus pneumoniae ( Spn ) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis.
Kruckow KL, Zhao K, Bowdish DME, Orihuela CJ.   +3 more
europepmc   +2 more sources

Hydrogen Peroxide Is Crucial for NLRP3 Inflammasome-Mediated IL-1β Production and Cell Death in Pneumococcal Infections of Bronchial Epithelial Cells. [PDF]

J Innate Immun, 2022
Epithelial cells play a crucial role in detection of the pathogens as well as in initiation of the host immune response. Streptococcus pneumoniae (pneumococcus) is a typical colonizer of the human nasopharynx, which can disseminate to the lower ...
Surabhi S, Jachmann LH, Shumba P, Burchhardt G, Hammerschmidt S, Siemens N.   +5 more
europepmc   +2 more sources

The Role of NLRP3 Inflammasome in Pneumococcal Infections. [PDF]

Front Immunol, 2020
Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli.
Surabhi S, Cuypers F, Hammerschmidt S, Siemens N.   +3 more
europepmc   +2 more sources

Pneumococcal infections and homelessness. [PDF]

J Prev Med Hyg, 2021
Objectif. To assess the prevalence of pneumococcal nasopharyngeal carriage, the role of potential risk factors, and vaccination against invasive pneumococcal diseases (IPD) among sheltered homeless persons (HP) in Marseille, France. Methods. In 2015 2018, we enrolled 571 sheltered homeless males and 54 non-homeless controls.
Ly TDA, Perieres L, Hoang VT, Dao TL, Gautret P.   +4 more
europepmc   +3 more sources

Economic burden of pneumococcal infections in children under 5 years of age. [PDF]

Hum Vaccin Immunother, 2018
The present study aimed to determine the cost of childhood pneumococcal infections under 5 years of age and to provide further data for future health economy studies.
Ceyhan M, Ozsurekci Y, Aykac K, Hacibedel B, Ozbilgili E.   +4 more
europepmc   +2 more sources

Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]

PLoS ONE, 2011
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono, Muneki Hotomi, Susan K Hollingshead, David E Briles, Noboru Yamanaka   +4 more
doaj   +2 more sources

The prevention of pneumococcal infections. [PDF]

Clin Exp Vaccine Res, 2016
Streptococcus pneumoniae causes considerable number of diseases like pneumonia, bacteremia or sepsis, meningitis, otitis media, sinusitis, peritonitis, endocarditis, osteomyelitis, septic arthritis, and soft tissue infection [1,2,3]. According to the Korean statistics of death, 12,021 people died of pneumonia during the year 2014, mortality is 23.7 per
Chang MS, Woo JH.
europepmc   +4 more sources

Incidence of Confirmed Influenza and Pneumococcal Infections and Vaccine Uptake Among Virologically Suppressed People Living with HIV [PDF]

Vaccines
Background/Objectives: Influenza and Streptococcus pneumoniae infections are common vaccine-preventable diseases to which people living with HIV (PLWH) may be more susceptible.
Edith Wolder Ejlersen, Josefine Amalie Loft, Marco Gelpi, Safura-Luise Heidari, Omid Rezahosseini, Johan Runge Poulsen, Dina Leth Møller, Zitta Barrella Harboe, Thomas Benfield, Susanne Dam Nielsen, Andreas Dehlbæk Knudsen   +10 more
doaj   +2 more sources

Pneumococcal carriage in sub-Saharan Africa--a systematic review. [PDF]

, 2014
BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV)
A Fenoll, A Kacou-N'Douba, A Kacou-N'douba, A Roca, A von Gottberg, A Woolfson, A Yomo, AB Brueggemann, AH Skalet, AK Rowe, Andrew Hall, B Frederiksen, B Oppenheim, BM Gray, BM Gray, C Levy, Caroline L. Trotter, Christian Bottomley, CL Trotter, D Bogaert, D Hansman, DB Blossom, DM Denno, DM Mwenya, DR Feikin, DR Feikin, E Varon, Effua Usuf, ES Donkor, EV Millar, G Regev-Yochay, GA Mackenzie, H Faden, H Rinta-Kokko, H Smith-Vaughan, HL Johnson, HT Vu, ID Rusen, JA Scott, JAG Scott, JD Kellner, JR Scott, KA Robinson, KL O'Brien, KL O'Brien, KP Klugman, L Marcus, L Pemba, LC Bere, LM McNally, M Antonio, M Guevara, M Mthwalo, MF Cotton, MK Darboe, MK Darboe, ML Joloba, MO Ota, MR Capeding, MR Jacobs, MW Mureithi, N Lloyd-Evans, N Mbelle, NOA Nwachukwu, O Abdullahi, O Abdullahi, PC Hill, PC Hill, PC Hill, PL Ho, PW Roche, R Dagan, RA Adegbola, RE Huebner, RE Huebner, Richard A. Adegbola, RK Syrjanen, RM Robins-Browne, RN Ndip, S Haug, S Yang, SB Gordon, SK Obaro, SK Obaro, SL Batt, SL Kaplan, SR Williams, SS Huang, WM Nyandiko, X Valles, YB Cheung, YT Kandakai-Olukemi   +91 more
core   +17 more sources

Association of Nonpharmaceutical Interventions During the COVID-19 Pandemic With Invasive Pneumococcal Disease, Pneumococcal Carriage, and Respiratory Viral Infections Among Children in France

JAMA Network Open, 2022
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak, C. Levy, F. Angoulvant, A. Auvrignon, P. Gembara, K. Danis, S. Vaux, D. Lévy-Bruhl, S. van der Werf, S. Béchet, S. Bonacorsi, Zein Assad, A. Lazzati, M. Michel, F. Kaguelidou, A. Faye, R. Cohen, E. Varon, N. Ouldali   +18 more
semanticscholar   +1 more source