BackgroundIncidence, manifestations and case-fatality rate (CFR) of invasive pneumococcal disease (IPD) vary with age and comorbidities. New vaccines, changing age distribution, prolonged survival among immunocompromised patients and improved sepsis ...
E. Backhaus +7 more
semanticscholar +1 more source
A 66 years old Caucasian woman with pneumococcal meningitis was treated and discharged after an uncomplicated course. Five months later she was readmitted withfever and right side abdominal pain and diagnosed with pneumococcal spondylodiscitis.
Shahin Gaini +3 more
doaj +1 more source
Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST +5 more
core +1 more source
Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S. +7 more
core +5 more sources
Pneumococcal Vaccination in Immunocompromised Hosts: An Update
Infections with the pathogen, Streptococcus pneumoniae, are a common cause of morbidity and mortality worldwide. It particularly affects those at the extremes of age and immunocompromised individuals.
Claire Froneman +2 more
doaj +1 more source
Nasopharyngeal (NP) pneumococcal carriage predisposes children to pneumococcal infections. Defining the proportion of pneumococcal isolates that are antibiotic-resistant enables the appropriate choice of empiric therapies.
Julie Y. Zhou +8 more
doaj +1 more source
The TRIP database showed most Acute Respiratory Infections questions were already addressed by Cochrane reviews [PDF]
OBJECTIVE: Cochrane systematic reviews require more methodological support from Cochrane Review Groups (CRGs) than is customary in journals, CRGs must prioritise reviews to conserve resources.
Brassey, Jon +4 more
core +1 more source
The ABC of pneumococcal infections and vaccination in patients with chronic kidney disease
Background In the general population, pneumococcal polysaccharide vaccines (PPV) decrease the incidence of invasive pneumococcal disease (IPD) whereas the impact on the prevention of noninvasive pneumococcal disease is less clear.
S. Vandecasteele +3 more
semanticscholar +1 more source
Pneumococcal vaccination among adults – updated Polish recommendations
Diseases caused by Streptococcus pneumoniae (S. pneumoniae) can be either invasive or non-invasive. In adults, pneumococcal infections most often occur as pneumonia, one of the leading causes of hospitalisation in these patients in Poland.
ERNEST KUCHAR +9 more
doaj +1 more source
Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland [PDF]
While acute respiratory tract infections can trigger cardiovascular events, the differential effect of specific organisms is unknown. This is important to guide vaccine policy.Using national infection surveillance data linked to the Scottish Morbidity ...
Andrew C. Hayward +9 more
core +3 more sources

