Results 11 to 20 of about 3,323,984 (317)

Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]

PLoS ONE, 2011
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono, Muneki Hotomi, Susan K Hollingshead, David E Briles, Noboru Yamanaka   +4 more
doaj   +2 more sources

Acute organ injury and long-term sequelae of severe pneumococcal infections. [PDF]

Pneumonia (Nathan), 2023
Streptococcus pneumoniae ( Spn ) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis.
Kruckow KL, Zhao K, Bowdish DME, Orihuela CJ.   +3 more
europepmc   +2 more sources

Hydrogen Peroxide Is Crucial for NLRP3 Inflammasome-Mediated IL-1β Production and Cell Death in Pneumococcal Infections of Bronchial Epithelial Cells. [PDF]

J Innate Immun, 2022
Epithelial cells play a crucial role in detection of the pathogens as well as in initiation of the host immune response. Streptococcus pneumoniae (pneumococcus) is a typical colonizer of the human nasopharynx, which can disseminate to the lower ...
Surabhi S, Jachmann LH, Shumba P, Burchhardt G, Hammerschmidt S, Siemens N.   +5 more
europepmc   +2 more sources

The Role of NLRP3 Inflammasome in Pneumococcal Infections. [PDF]

Front Immunol, 2020
Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli.
Surabhi S, Cuypers F, Hammerschmidt S, Siemens N.   +3 more
europepmc   +2 more sources

Economic burden of pneumococcal infections in children under 5 years of age. [PDF]

Hum Vaccin Immunother, 2018
The present study aimed to determine the cost of childhood pneumococcal infections under 5 years of age and to provide further data for future health economy studies.
Ceyhan M, Ozsurekci Y, Aykac K, Hacibedel B, Ozbilgili E.   +4 more
europepmc   +2 more sources

Association of Nonpharmaceutical Interventions During the COVID-19 Pandemic With Invasive Pneumococcal Disease, Pneumococcal Carriage, and Respiratory Viral Infections Among Children in France

JAMA Network Open, 2022
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak, C. Levy, F. Angoulvant, A. Auvrignon, P. Gembara, K. Danis, S. Vaux, D. Lévy-Bruhl, S. van der Werf, S. Béchet, S. Bonacorsi, Zein Assad, A. Lazzati, M. Michel, F. Kaguelidou, A. Faye, R. Cohen, E. Varon, N. Ouldali   +18 more
semanticscholar   +1 more source

Fulminant pneumococcal infection [PDF]

BMJ Case Reports, 2014
SummaryFulminant pneumococcal infection is a fatal pneumococcal infection that tends to occur in immunocompromised hosts, such as patients who are asplenic or on immunosuppressant therapy. We experienced a case of a 73-year-old Japanese man with a medical history of coronary stent implantation and catheter ablation for atrial flutter who presented with
Ryo, Naito, Tetsuro, Miyazaki, Kazunori, Kajino, Hiroyuki, Daida   +3 more
openaire   +2 more sources

The Health Professional’s View on the Inclusion of Age in the Recommendations for Pneumococcal Vaccination: Results of a Cross-Sectional Survey in France

Geriatrics, 2021
Elderly people are at high risk for pneumococcal infections. However, older age is not an eligibility factor for pneumococcal vaccination in France. Adults with certain co-morbidities or immunocompromised states are eligible for vaccination, which leaves
Gaëlle Farge, Benoît de Wazières, Jocelyn Raude, Clémence Delavelle, Fabienne Humbert, Cécile Janssen   +5 more
doaj   +1 more source

No temporal association between influenza outbreaks and invasive pneumococcal infections [PDF]

, 2008
Objective: To assess whether the influenza peak in populations precedes the annual peak for invasive pneumococcal infections (IPI) in winter.Design: Ecological study.
Arenz, Stephan, Heininger, Ulrich, Kries, Wolfram and Weigl, Toschke, Andre Michael   +3 more
core   +1 more source

The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Pneumococcal Nasal Colonization and Subsequent Development of Invasive Disease

Frontiers in Immunology, 2021
Transient receptor potential (TRP) channels, neuronal stimulations widely known to be associated with thermal responses, pain induction, and osmoregulation, have been shown in recent studies to have underlying mechanisms associated with inflammatory ...
Masamitsu Kono, Denisa Nanushaj, Hideki Sakatani, Daichi Murakami, Masayoshi Hijiya, Tetsuya Kinoshita, Tatsuya Shiga, Fumie Kaneko, Keisuke Enomoto, Gen Sugita, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotomi   +13 more
doaj   +1 more source