Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring. [PDF]
Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci ...
Masamitsu Kono+4 more
doaj +2 more sources
Acute organ injury and long-term sequelae of severe pneumococcal infections. [PDF]
Streptococcus pneumoniae ( Spn ) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis.
Kruckow KL+3 more
europepmc +2 more sources
The Role of NLRP3 Inflammasome in Pneumococcal Infections. [PDF]
Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation in response to environmental, host- and pathogen-derived factors. The NLRP3 inflammasome is highly versatile as it is activated by a diverse range of stimuli.
Surabhi S+3 more
europepmc +2 more sources
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak+18 more
semanticscholar +1 more source
Adult pneumococcal vaccination – new opportunities
Pneumococcal infections (Streptococcus pneumoniae) remain a significant epidemiological problem globally. Although an invasive pneumo-coccal disease (IPD), which includes meningitis, sepsis and pneumonia with bacteremia, is the most severe form of ...
ERNEST KUCHAR+13 more
doaj +1 more source
Biofilm-associated infections are of great concern because they are associated with antibiotic resistance and immune evasion. Co-colonization by Staphylococcus aureus and Streptococcus pneumoniae is possible and a threat in clinical practice.
Julio Sempere+7 more
doaj +1 more source
Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales [PDF]
England and Wales recently replaced the 7-valent pneumococcal conjugate vaccine (PCV7) with its 13-valent equivalent (PCV13), partly based on projections from mathematical models of the long-term impact of such a switch compared to ceasing pneumococcal ...
A Melegaro+21 more
core +9 more sources
Promising Expectations for Pneumococcal Vaccination during COVID-19
The emergence of new viral infections has increased over the decades. The novel virus is one such pathogen liable for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, popularly known as coronavirus disease 2019 (COVID-19).
Hyobin Im+3 more
doaj +1 more source
Visualizing Pneumococcal Infections in the Lungs of Live Mice Using Bioluminescent Streptococcus pneumoniae Transformed with a Novel Gram-Positive lux Transposon [PDF]
Kevin P. Francis+9 more
openalex +2 more sources
Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source