Results 31 to 40 of about 3,242,948 (272)

The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Pneumococcal Nasal Colonization and Subsequent Development of Invasive Disease

Frontiers in Immunology, 2021
Transient receptor potential (TRP) channels, neuronal stimulations widely known to be associated with thermal responses, pain induction, and osmoregulation, have been shown in recent studies to have underlying mechanisms associated with inflammatory ...
Masamitsu Kono, Denisa Nanushaj, Hideki Sakatani, Daichi Murakami, Masayoshi Hijiya, Tetsuya Kinoshita, Tatsuya Shiga, Fumie Kaneko, Keisuke Enomoto, Gen Sugita, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotomi   +13 more
doaj   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

House Dust Mite Aeroallergen Suppresses Leukocyte Phagocytosis and Netosis Initiated by Pneumococcal Lung Infection

Frontiers in Pharmacology, 2022
Asthmatics are highly susceptible to developing lower respiratory tract infections caused by Streptococcus pneumoniae (SPN, the pneumococcus). It has recently emerged that underlying allergic airway disease creates a lung microenvironment that is ...
Angelica Papanicolaou, Hao Wang, Jonathan McQualter, Christian Aloe, Stavros Selemidis, Catherine Satzke, Catherine Satzke, Catherine Satzke, Ross Vlahos, Steven Bozinovski   +9 more
doaj   +1 more source

Invasive pneumococcal infections in children following transplantation in the pneumococcal conjugate vaccine era

Transplant Infectious Disease, 2015
Pediatric recipients of hematopoietic stem cell and solid organ transplants are at increased risk of invasive pneumococcal infections (IPI). Data on IPI in this population are scarce.
Liset Olarte, P. Lin, W. Barson, J. Romero, T. Tan, L. Givner, J. Hoffman, J. Bradley, K. Hulten, E. Mason, S. Kaplan   +10 more
semanticscholar   +1 more source

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Microbiology spectrum, 2022
Pneumococcal pneumonia has been a significant cause of morbidity and mortality throughout human history. Failing to control pneumococcal pneumonia and resolve ongoing inflammation in a host can cause sepsis, namely pneumococcal pneumosepsis, and death ...
X. Gou, Wenchun Xu, Yusi Liu, Yang Peng, Wenlong Xu, Yibing Yin, Xuemei Zhang   +6 more
semanticscholar   +1 more source

Prevention of pneumococcal diseases in the post-seven valent vaccine era: A European perspective

BMC Infectious Diseases, 2012
Background The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S.
Weil-Olivier Catherine, van der Linden Mark, de Schutter Iris, Dagan Ron, Mantovani Lorenzo   +4 more
doaj   +1 more source

Impact of infection preventionists on Centers for Medicare and Medicaid quality measures in Maryland nursing homes. [PDF]

, 2014
BackgroundHealth care-associated infections are the leading cause of morbidity and mortality in US nursing homes (NHs). The objective of the research is to assess the impact of Maryland NH infection preventionists (IPs) on NH quality measures.MethodsTwo ...
Castle, Nicholas G, Roup, Brenda J, Wagner, Laura M   +2 more
core   +1 more source

The ABC of pneumococcal infections and vaccination in patients with chronic kidney disease

Clinical Kidney Journal, 2015
Background In the general population, pneumococcal polysaccharide vaccines (PPV) decrease the incidence of invasive pneumococcal disease (IPD) whereas the impact on the prevention of noninvasive pneumococcal disease is less clear.
S. Vandecasteele, S. Ombelet, S. Blumental, W. Peetermans   +3 more
semanticscholar   +1 more source

Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue [PDF]

, 2011
Background. Streptococcus pneumoniae causes serious diseases such as pneumonia and meningitis. Its major pathogenic factor is the cholesterol-dependent cytolysin pneumolysin, which produces lytic pores at high concentrations.
Asparouh I. Iliev, Ben-Abraham, Benz, Benz, Benz, Bereczki, Beurg, Braun, Carolin Wippel, Christina Förtsch, Cooper, Douce, Durand, Elke Maier, Fickl, Franco-Vidal, Förtsch, Hirst, Iliev, Iliev, Iliev, Jiangtao Ma, Johnson, Jones, Korchev, Korchev, Ohba, Orlov, Pandey, Reiss, Roland Benz, Sabrina Hupp, Somjen, Spreer, Stringaris, Tilley, Timothy J. Mitchell, Wellmer, Wood, Zaloga, Zefirov   +40 more
core   +3 more sources

Decline in Pneumococcal Disease in Young Children during the COVID-19 Pandemic in Israel Associated with Suppression of seasonal Respiratory Viruses, despite Persistent Pneumococcal Carriage: A Prospective Cohort Study

Clinical Infectious Diseases, 2021
Background The incidence of invasive pneumococcal disease (IPD) declined during the COVID-19 pandemic. Previous studies hypothesized that this was due to reduced pneumococcal transmission resulting from non-pharmaceutical interventions.
D. Danino, S. Ben-Shimol, B. A. van der Beek, N. Givon‐Lavi, Y. Avni, D. Greenberg, D. Weinberger, R. Dagan   +7 more
semanticscholar   +1 more source