Results 31 to 40 of about 3,296,751 (334)

Pneumococcal carriage, serotype distribution and risk factors in children with community-acquired pneumonia, 5 years after introduction of the 10-valent pneumococcal conjugate vaccine in Ethiopia [PDF]

, 2019
Background: There is a scarcity of data on pneumococcal serotypes carried by children in Ethiopia. We studied pneumococcal nasopharyngeal carriage rate, serotypes, and risk factors among children with community acquired pneumonia (CAP).
Abebe, Workeabeba, Aseffa, Abraham, Asrat, Daniel, Gebre, Meseret, Hailemariam, Tewodros, Negash, Abel Abera, Vaneechoutte, Mario, Verhaegen, Jan   +7 more
core   +1 more source

House Dust Mite Aeroallergen Suppresses Leukocyte Phagocytosis and Netosis Initiated by Pneumococcal Lung Infection

Frontiers in Pharmacology, 2022
Asthmatics are highly susceptible to developing lower respiratory tract infections caused by Streptococcus pneumoniae (SPN, the pneumococcus). It has recently emerged that underlying allergic airway disease creates a lung microenvironment that is ...
Angelica Papanicolaou, Hao Wang, Jonathan McQualter, Christian Aloe, Stavros Selemidis, Catherine Satzke, Catherine Satzke, Catherine Satzke, Ross Vlahos, Steven Bozinovski   +9 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A., Chain, B., Deretic, V., Dockrell, D.H., Francis, S.E., Kroemer, G., Marriott, H.M., Mitchell, T.J., Read, R.C., Tulone, C., Whyte, M.K.B.   +10 more
core   +5 more sources

Prevention of pneumococcal diseases in the post-seven valent vaccine era: A European perspective

BMC Infectious Diseases, 2012
Background The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S.
Weil-Olivier Catherine, van der Linden Mark, de Schutter Iris, Dagan Ron, Mantovani Lorenzo   +4 more
doaj   +1 more source

Invasive pneumococcal infections in children following transplantation in the pneumococcal conjugate vaccine era

Transplant Infectious Disease, 2015
Pediatric recipients of hematopoietic stem cell and solid organ transplants are at increased risk of invasive pneumococcal infections (IPI). Data on IPI in this population are scarce.
Liset Olarte, P. Lin, W. Barson, J. Romero, T. Tan, L. Givner, J. Hoffman, J. Bradley, K. Hulten, E. Mason, S. Kaplan   +10 more
semanticscholar   +1 more source

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Microbiology spectrum, 2022
Pneumococcal pneumonia has been a significant cause of morbidity and mortality throughout human history. Failing to control pneumococcal pneumonia and resolve ongoing inflammation in a host can cause sepsis, namely pneumococcal pneumosepsis, and death ...
X. Gou, Wenchun Xu, Yusi Liu, Yang Peng, Wenlong Xu, Yibing Yin, Xuemei Zhang   +6 more
semanticscholar   +1 more source

Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization. [PDF]

, 2020
Background:Inadequate titers of pneumococcal antibody (PA) are commonly present among patients with recurrent respiratory infections. Objective:We sought to determine the effect of the degree of inadequacy in baseline PA titers on the subsequent ...
Chernikova, Diana, Estevez, Dennys, Hernandez, Francesca, Sakai-Bizmark, Rie, Song, Charles H, Stiehm, Richard   +5 more
core  

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds, AM Faria, C Jokinen, C Laine, C O'Mahony, Carlos Javier Orihuela, D Bogaert, DM Musher, EJ Novak, EK Mulholland, EM Laughlin, G Oldenhove, H Christensen, HM Foy, HW Lim, I Rudan, JC Paton, Jeffrey Pido-Lopez, JL Round, JN Stoop, K Wing, KA Robinson, L Strauss, L Weiss, M Hara, M Hussain, M Lipsitch, M Livingston, M Quigley, MJ Butte, MJ van Kempen, MW Mureithi, N Iikuni, Neil A. Williams, PC Hill, PR Myles, Q Zhang, Q Zhang, Q Zhang, R Austrian, R Malley, R Malley, RM Wong, Robert S. Heyderman, S Hori, S Paust, S Rapola, S Read, S Sakaguchi, S Sakaguchi, SE Sandner, SK Obaro, SQ Crome, T Sturniolo, T Takahashi, Timothy J. Mitchell, V Davenport, William W. Kwok, X Zhang, Y Belkaid, Y Cong, YJ Lu, Z Zhang   +62 more
core   +3 more sources

Pneumococcal infection in the newborn. [PDF]

Archives of Disease in Childhood, 1993
Two fatal cases of invasive pneumococcal disease in the newborn are reported, both acquired from the maternal vagina. The rarity of vaginal carriage of pneumococcus suggests that this organism has a higher invasion to colonisation ratio than group B streptococcus and maternal carriage or neonatal colonisation should be more aggressively treated.
R C Spencer, M S Tanner, R A Primhak
openaire   +3 more sources

Meningitis, spondylodiscitis, pneumonia and septic shock with Streptococcus pneumoniae in a previously healthy woman with isolated IgG2-, IgG3-, IgA-deficiency and monoclonal gammopathy of undetermined significance

Infectious Disease Reports, 2018
A 66 years old Caucasian woman with pneumococcal meningitis was treated and discharged after an uncomplicated course. Five months later she was readmitted withfever and right side abdominal pain and diagnosed with pneumococcal spondylodiscitis.
Shahin Gaini, David Gudnason, Bjarni á Steig, Jenny Jónsdóttir Nielsen   +3 more
doaj   +1 more source