Results 41 to 50 of about 76,738 (248)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Optimal age targeting for pneumococcal vaccination in older adults; a modelling study

Nature Communications, 2023
Vaccination against invasive pneumococcal disease is recommended for older adults but the optimal age group to target has not been determined and may vary by epidemiological setting.
Deus Thindwa, Samuel Clifford, Jackie Kleynhans, Anne von Gottberg, Sibongile Walaza, Susan Meiring, Todd D. Swarthout, Elizabeth Miller, Peter McIntyre, Nick Andrews, Zahin Amin-Chowdhury, Norman Fry, Kondwani C. Jambo, Neil French, Samanta Cristine Grassi Almeida, Shamez N. Ladhani, Robert S. Heyderman, Cheryl Cohen, Maria Cristina de Cunto Brandileone, Stefan Flasche   +19 more
doaj   +1 more source

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]

, 2011
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith, Aspa, Austrian, Avery, Blake, Cecil, Chris Robertson, David Greenhalgh, Diggle, Donald Inverarity, Giles F. S. Edwards, Guimbao Bescós, Huss, Inostroza, Jim McMenamin, Johanna M. C. Jefferies, Karen Lamb, Kendrick, Lamb, Martin, Mathew Diggle, Shapiro, Stuart C. Clarke, Tim J. Mitchell, Weiss   +24 more
core   +3 more sources

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]

, 2019
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

COVID‐19 Vaccination is not Associated with the Development of Idiopathic Inflammatory Myositis in U.S. Veterans

Arthritis Care &Research, Accepted Article.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J Braaten, Gary A Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea [PDF]

Korean Journal of Pediatrics, 2011
Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults.
Eun Hwa Choi, Kyung Hyo Kim, Yae Jean Kim, Jong Hyun Kim, Su Eun Park, Hoan Jong Lee, Byung Wook Eun, Dae Sun Jo, Kyong Min Choi, Young Jin Hong   +9 more
doaj   +1 more source

P-59. Clinical predictors of ICU admission in patients with invasive Pneumococcal blood stream infection: a review of 10-year single-center experience [PDF]

Open Forum Infect Dis
Ayesha Samreen, Rita Igwilo-Alaneme, Nischal Ranganath, Omar M Abu Saleh   +3 more
openalex   +2 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Exploring the evidence base for national and regional policy interventions to combat resistance [PDF]

, 2015
The effectiveness of existing policies to control antimicrobial resistance is not yet fully understood. A strengthened evidence base is needed to inform effective policy interventions across countries with different income levels and the human health and
Aarestrup, Aarestrup, Ahuja, Aidara-Kane, Alimuddin Zumla, Allegranzi, Allegranzi, Amábile-Cuevas, Anthony D So, Anthony Kessel, Baertlein, Belongia, Belongia, Bushnell, Catley, Catley, Cheng, Coenen, Crowther-Gibson, Dagan, Datema, Davey, David L Heymann, De Boeck, Earnshaw, Emmeline J Buckley, Fazal K Dar, Finkelstein, Fätkenheuer, Gerber, Govin Permanand, Grave, Grave, Grazia Caleo, Grundmann, Hammerum, Hanne Bak Pedersen, Harbarth, Haydar Giha, Hennessy, Henry Lishi Li, Heuer, Holloway, Huttner, Huttner, Jack, Jasper Littmann, John-Arne Røttingen, Jørgen Schlundt, Kariuki, Katakweba, Khalid M Bindayna, Khan, Komolafe, Kümmerer, Little, Luoto, Mandal, Mark Rweyemamu, Marti, McNulty, Mishal Khan, Mitj, Mohammed Shahid, Moyane, Mshana, Nisi, Ogan, Okeke, Okeke, Okeke, Osman A Dar, Parry, Pittet, Pletz, Radley, Ranji, Richard Kock, Rumina Hasan, Silverman, Simonsen, Song, Speksnijder, Spurling, Stephan Harbarth, Vanden Eng, Vernet, Versporten, Versporten, Viberg, Vlieghe, Walt, Xiao, Zingg   +93 more
core   +2 more sources