Results 61 to 70 of about 42,790 (192)

Predicting optimal impact interventions in the post‐HPV vaccination world

International Journal of Cancer, Volume 158, Issue 9, Page 2262-2271, 1 May 2026.
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen, Marc Lipsitch, Ville N. Pimenoff, Karin Sundström, Johannes Berkhof, Iacopo Baussano, Simopekka Vänskä, Joakim Dillner   +7 more
wiley   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, Volume 78, Issue 4, Page 512-519, April 2026.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Will Extended‐Valency Pneumococcal Conjugate Vaccines Offer Enhanced Coverage Against Invasive Pneumococcal Disease for At‐Risk Children?

Acta Paediatrica, EarlyView.
Robert Cohen, Corinne Levy, Naim Ouldali, Stéphane Béchet, Aude Estivaux, André Birgy, Isabelle Hau, IPD Study Group, Emmanuelle Varon   +8 more
wiley   +1 more source

Creative and Adaptive Solutions for Early Diagnosis of Sickle Cell Disease in Sub‐Saharan Africa

American Journal of Hematology, Volume 101, Issue S1, Page 17-32, April 2026.
ABSTRACT Many of the children with sickle cell disease born in sub‐Saharan Africa remain undiagnosed and untreated. Increasing capacity and infrastructure to support diagnostic and screening programs in high income countries have enabled near universal survival into adulthood.
Luke R. Smart, Catherine I. Segbefia, Isaac Odame   +2 more
wiley   +1 more source

The Epidemiology of Sickle Cell Disease in Sub‐Saharan Africa: Current Knowledge and Gaps to be Filled

American Journal of Hematology, Volume 101, Issue S1, Page 5-16, April 2026.
What are the available data on incidence & prevalence prognosis risk factors of severity of sickle cell disease in sub‐Saharan Africa? ABSTRACT Sickle Cell Disease (SCD) is highly prevalent in sub‐Saharan Africa. Epidemiological data remain sparse, but regional screening and research initiatives are expanding.
Brigitte Ranque, Leon Tshilolo, Thomas N. Williams   +2 more
wiley   +1 more source

Global Control of Pneumococcal Infections by Pneumococcal Vaccines

Tropical Medicine and Health, 2014
Streptococcus pneumoniae is a major worldwide cause of morbidity and mortality. Pneumococcal carriage is considered to be an important source of horizontal spread of this pathogen within the community. Pneumococcal conjugate vaccine (PCV) is capable of inducing serotype-specific antibodies in sera of infants, and has been suggested to reduce ...
Oishi, Kazunori, Tamura, Kazuyo, Akeda, Yukihiro   +2 more
openaire   +3 more sources

Microbial Etiology and Antimicrobial Resistance in Pneumonia Among Hospitalized Patients in Kazakhstan: A Systematic Review and Single‐Arm Meta‐Analysis of Prevalence Data

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Pneumonia is an inflammatory condition of the lower respiratory tract, commonly caused by infection and associated with substantial morbidity and healthcare utilization. The burden of pneumonia on healthcare is exacerbated by limited data on pathogenic causes and associated antimicrobial resistance (AMR). Here, we conducted
Radmir Sarsenov, Maxim Solomadin, Alyona Lavrinenko, Vyacheslav Beloussov, Vitaliy Strochkov, Shynggys Orkara, Nurlan Sandybayev, Sergey Yegorov   +7 more
wiley   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

EBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield   +8 more
doaj   +1 more source

The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection.

PLoS Pathogens, 2020
Streptococcus pneumoniae is a major human pathogen, causing pneumonia and sepsis. Genetic components strongly influence host responses to pneumococcal infections, but the responsible loci are unknown.
Vitor E Fernandes, Giuseppe Ercoli, Alan Bénard, Carolin Brandl, Hannah Fahnenstiel, Jennifer Müller-Winkler, Georg F Weber, Paul Denny, Lars Nitschke, Peter W Andrew   +9 more
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source