Results 21 to 30 of about 29,361 (134)

Burden of pneumococcal disease in children in Cuba before the introduction of a novel pneumococcal conjugate vaccine

Journal of Global Health Reports, 2019
# Background The Cuban heptavalent conjugate pneumococcal vaccine will be introduced for children beginning in 2020. We estimated the burden of pneumococcal cases and deaths in children 1-59 months in 2015.
Nivaldo Linares-Pérez, Brian Wahl, Misladys Rodriguez, Gilda Toraño, María E. Toledo-Romaní   +4 more
doaj   +1 more source

The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions. [PDF]

PLoS ONE, 2012
Recent studies have shown that most of deaths in the 1918 influenza pandemic were caused by secondary bacterial infections, primarily pneumococcal pneumonia.
Yu-Wen Chien, Bruce R Levin, Keith P Klugman   +2 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Scheduling early primary care follow‐up after pneumonia: A retrospective target trial emulation in five hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis, Stephanie P. Taylor, Catherine L. Hough, Mari Armstrong‐Hough, Li Yan, Catherine K. Ettman, Katy Sadowski, Khyzer B. Aziz, Patrick G. Lyons, Katrina E. Hauschildt, Marc Kowalkowski, Eliana M. Perrin, Theodore J. Iwashyna   +12 more
wiley   +1 more source

A model for predicting bacteremia in patients with community-acquired pneumococcal pneumonia: a retrospective observational study

BMC Pulmonary Medicine, 2018
Background Pneumococcal pneumonia causes high morbidity and mortality among adults. This study aimed to identify risk factors for bacteremic pneumococcal pneumonia, and to construct a prediction model for the development of bacteremia in patients with ...
Yasuyoshi Washio, Akihiro Ito, Shogo Kumagai, Tadashi Ishida, Akio Yamazaki   +4 more
doaj   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

A population-based study on the burden of hospitalized pediatric pneumococcal disease in Taiwan before and after the introduction of 13-valent pneumococcal conjugate vaccine into the childhood immunization program in 2015

BMC Infectious Diseases
Background To estimate the burden of invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, and acute otitis media before and after inclusion of the 13-valent pneumococcal vaccine (PCV13) into Taiwan’s Childhood Immunization Program in ...
Ting-An Yen, Jhong-Lin Wu, Chi-Chuan Wang, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Thiow Koon Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom   +9 more
doaj   +1 more source

Targeting the Dynamic Susceptibility Window: Time‐Sensitive Photodynamic Synergy With Antibiotics Against Streptococcus spp

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective Evaluated the antimicrobial efficacy of curcumin‐mediated photodynamic inactivation (PDI) against both sensitive and resistant strains of Streptococcus pneumoniae and Streptococcus pyogenes, as well as its potential to enhance antibiotic effects (amoxicillin, ceftriaxone, erythromycin).
Isabella S. Gonçalves, Jennifer M. Soares, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

BMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy, Kristen E. Allen, Mark A. Fletcher, Kok Fui Liew, Boekhtiar Borhanuddin, Mohammad Ali, Graciela Morales, Bradford Gessner, Jerusha Naidoo, Jo Southern   +9 more
doaj   +1 more source

A Retrospective Study of the Clinical Burden of Hospitalized All-Cause and Pneumococcal Pneumonia in Canada

Canadian Respiratory Journal, 2016
Background. Routine vaccination against Streptococcus pneumoniae is recommended in Canada for infants, the elderly, and individuals with chronic comorbidity.
Shelly A. McNeil, Nawab Qizilbash, Jian Ye, Sharon Gray, Giovanni Zanotti, Samantha Munson, Nathalie Dartois, Craig Laferriere   +7 more
doaj   +1 more source