Results 71 to 80 of about 30,753 (249)

The Safety of 12‐Weekly Monitoring of Neutrophil Count in Long‐Term Clozapine Patients

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Clozapine is the only truly effective treatment for refractory schizophrenia, but its use is constrained by the requirements for frequent monitoring of neutrophil counts. In the UK during the COVID‐19 pandemic, the frequency of clozapine blood monitoring was reduced in some units from 4‐weekly to 12‐weekly. We aimed to investigate
David Taylor, Siobhan Gee, Marinka Helthuis, Ebenezer Oloyede   +3 more
wiley   +1 more source

Herd effects of child vaccination with pneumococcal conjugate vaccine against pneumococcal non-invasive community-acquired pneumonia: What is the evidence?

Human Vaccines & Immunotherapeutics, 2017
Quantification of pneumococcal conjugate vaccines (PCVs) herd effects are mainly performed on invasive pneumococcal disease (IPD) but there is conflicting evidence regarding herd effects of PCVs on non-IPD pneumococcal community-acquired pneumonia.
Cornelis H. van Werkhoven
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A., Chain, B., Deretic, V., Dockrell, D.H., Francis, S.E., Kroemer, G., Marriott, H.M., Mitchell, T.J., Read, R.C., Tulone, C., Whyte, M.K.B.   +10 more
core   +4 more sources

A population-based study on the burden of hospitalized pediatric pneumococcal disease in Taiwan before and after the introduction of 13-valent pneumococcal conjugate vaccine into the childhood immunization program in 2015

BMC Infectious Diseases
Background To estimate the burden of invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, and acute otitis media before and after inclusion of the 13-valent pneumococcal vaccine (PCV13) into Taiwan’s Childhood Immunization Program in ...
Ting-An Yen, Jhong-Lin Wu, Chi-Chuan Wang, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Thiow Koon Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom   +9 more
doaj   +1 more source

Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand - comparison of Bayesian latent class modeling and conventional analysis

BMC Infectious Diseases, 2019
Background Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, have been used to estimate prevalence
Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett, Christopher J. Gregory   +11 more
doaj   +1 more source

Evaluation of the pneumococcal urinary antigen test (PUT): a retrospective study

Fujita Medical Journal, 2021
Objectives: To determine the usefulness of the pneumococcal urinary antigen test (PUT) and to describe the characteristics of pneumococcal pneumonia.
Tatsuyoshi Yokoi, Kazunobu Kuwabara, Kiyotaka Ono, Yusuke Kito, Kenichi Kato, Keisuke Kato, Masahiro Hirose, Rieko Kondo, Takahiko Horiguchi   +8 more
doaj   +1 more source

Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]

, 2004
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S., Simon, Michelle, Kumar, Saumya, Fernandes, Vitor E., Sylvius, Nicolas, Mallon, Ann-Marie, Denny, Paul, Andrew, Peter W.   +7 more
core   +5 more sources

A Retrospective Study of the Clinical Burden of Hospitalized All-Cause and Pneumococcal Pneumonia in Canada

Canadian Respiratory Journal, 2016
Background. Routine vaccination against Streptococcus pneumoniae is recommended in Canada for infants, the elderly, and individuals with chronic comorbidity.
Shelly A. McNeil, Nawab Qizilbash, Jian Ye, Sharon Gray, Giovanni Zanotti, Samantha Munson, Nathalie Dartois, Craig Laferriere   +7 more
doaj   +1 more source

Cross-sectional study on attitudes among general practitioners towards pneumococcal vaccination for middle-aged and elderly population in Hong Kong. [PDF]

PLoS ONE, 2013
OBJECTIVE: To study the attitudes among general practitioners towards pneumococcal vaccination for middle-aged (50-64) and elderly population (over 65) in Hong Kong and the factors affecting their decision to advise pneumococcal vaccination for those age
Lancelot W H Mui, Alvin Y S Chan, Albert Lee, John Lee   +3 more
doaj   +1 more source

Adults aged 65 years and older in South Africa have a responsibility to vaccinate against influenza

Developing World Bioethics, EarlyView.
Abstract In this article, we draw on the thinking about incompleteness and conviviality grounded in Afro‐communitarianism ethics from the Global South to argue that adults aged 65 years and above have a prima facie responsibility to vaccinate against influenza.
Ruach Sarangarajan, Cornelius Ewuoso
wiley   +1 more source