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Current Opinion in Infectious Diseases, 2016
Pneumococcal diseases (invasive diseases, pneumonia, otitis media, and sinusitis) are among the most frequent preventable infectious diseases carrying a very high morbidity and case fatality rate worldwide. Pneumococcal vaccination is a key element to reduce the global burden of the disease in children and adult population.
Catia, Cillóniz +2 more
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Pneumococcal diseases (invasive diseases, pneumonia, otitis media, and sinusitis) are among the most frequent preventable infectious diseases carrying a very high morbidity and case fatality rate worldwide. Pneumococcal vaccination is a key element to reduce the global burden of the disease in children and adult population.
Catia, Cillóniz +2 more
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Pediatrics In Review, 1996
Streptococcus pneumoniae, commonly termed the pneumococcus, is a major pediatric pathogen both in developed and developing countries. Despite the availability of multiple antimicrobials to which this organism is susceptible, it continues to cause significant morbidity and mortality. Recognition of the limitations of antimicrobial therapy in controlling
G, Peter, J O, Klein
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Streptococcus pneumoniae, commonly termed the pneumococcus, is a major pediatric pathogen both in developed and developing countries. Despite the availability of multiple antimicrobials to which this organism is susceptible, it continues to cause significant morbidity and mortality. Recognition of the limitations of antimicrobial therapy in controlling
G, Peter, J O, Klein
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Drugs of Today, 1999
Despite advances in our knowledge of the pathogenesis and host immune response and efforts at prevention and treatment, S. pneumoniae continues to cause considerable disease and mortality. The currently available polysaccharide vaccines confer moderate protection in most adults and older children, but they are underutilized.
J D, Campbell, M B, Rennels
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Despite advances in our knowledge of the pathogenesis and host immune response and efforts at prevention and treatment, S. pneumoniae continues to cause considerable disease and mortality. The currently available polysaccharide vaccines confer moderate protection in most adults and older children, but they are underutilized.
J D, Campbell, M B, Rennels
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Pneumococcal Vaccination in Adults
AJN, American Journal of Nursing, 2023ABSTRACT: The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices recently updated the adult pneumococcal vaccine recommendations to include two new pneumococcal conjugate vaccines (PCVs): PCV15 and PCV20.
Joseph, Walter, Nicole, Rudawsky
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Pediatric Clinics of North America, 2000
Streptococcus pneumoniae or pneumococcus is a major pathogen causing meningitis, pneumonia, other invasive infections, and the common infections acute otitis media and sinusitis. The major virulence factor is the polysaccharide capsule, present as one of approximately 90 serotypes. Anticapsular antibodies protect against infection.
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Streptococcus pneumoniae or pneumococcus is a major pathogen causing meningitis, pneumonia, other invasive infections, and the common infections acute otitis media and sinusitis. The major virulence factor is the polysaccharide capsule, present as one of approximately 90 serotypes. Anticapsular antibodies protect against infection.
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Pneumococcal Infection and Pneumococcal Vaccine
New England Journal of Medicine, 1977The pneumococcus (Streptococcus pneumoniae) is a major cause of pneumonia, otitis media and meningitis throughout the world. Although the mortality resulting from pneumococcal infection has declined strikingly since the introduction of the sulfonamides, penicillin and other antibiotics, what limited epidemiologic evidence is available suggests that the
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Pneumococcal conjugate vaccines
Immunology Letters, 1991We have prepared conjugates of pneumococcal type 4 polysaccharides (PS4) or oligosaccharides to tetanus toxoid using the carbodiimide method. The use of a spacer, 6-aminohexanoic acid, resulted in higher incorporation of carrier protein. Conjugates contained up to 10% free polysaccharide, but no free protein.
C C, Peeters +6 more
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Pneumococcal Infections and Pneumococcal Vaccine: An Update
Infection Control, 1982AbstractPneumococcal pneumonia continues to be an important disease in terms of prevalence, morbidity and mortality. With the discovery of penicillin and its wide clinical use, the overall mortality of pneumococcal pneumonia has been significantly reduced, but problems remain.
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Correction: Pneumococcal Vaccine and Pneumococcal Pneumonia
Annals of Internal Medicine, 1988Excerpt To the Editor:Sims and colleagues made the following statement in their article on pneumococcal vaccine (1): Studies of sufficient statistical power have consistently shown the efficacy of ...
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