ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth +13 more
wiley +1 more source
Introduction Africa harbours a high burden of pneumococcal disease, with associated high mortality rates. Despite 34 countries introducing the pneumococcal conjugate vaccine, which reduces the risk of pneumococcal carriage (a prerequisite for disease) of
Neil French +7 more
doaj +1 more source
The association between life events, social support, and antibody status following thymus-dependent and thymus-independent vaccinations in healthy young adults [PDF]
This study determined whether stressful life events and social support were related to antibody status following both thymus-dependent and thymus-independent vaccinations. Life events in the previous year and customary social support were measured in 57
Burns, Victoria E. +4 more
core +1 more source
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Wang Chun Kwok +8 more
wiley +1 more source
Serotypes in Adult Pneumococcal Pneumonia in Spain in the Era of Conjugate Vaccines [PDF]
Lucía Fernández-Delgado +10 more
openalex +1 more source
Phase I, randomized, observer-blind, placebo-controlled studies to evaluate the safety, reactogenicity and immunogenicity of an investigational non-typeable Haemophilus influenzae (NTHi) protein vaccine in adults [PDF]
Background: Non-typeable Haemophilus influenzae (NTHi) is a major cause of various respiratory diseases. The development of an effective vaccine against NTHi mandates new approaches beyond conjugated vaccines as this opportunistic bacterium is non ...
Aris, Emmanuel +7 more
core +2 more sources
Improving Pneumococcal Vaccination Rates in Jefferson Hospital Ambulatory Practice Patients [PDF]
AIM: To improve the pneumococcal vaccination initiation rates in patients 65 years and older in Jefferson Hospital Ambulatory Practice (JHAP) to the institutional quality measure goal of 80% over a 4 month period from January to May of 2017.https://jdc ...
Enriquez, MD, Matthew +3 more
core +1 more source
A Systematic Review on Travel Medicine Practice to Control Transmission of Communicable Diseases [PDF]
Background: The number of international travelers is estimated at 900 million per year and is projected to reach 1.6 billion per year in 2020. Travel medicine is devoted to the health of travelers who visit foreign countries.
Bachtiar, A. (Adang ) +1 more
core +1 more source
Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín +5 more
wiley +1 more source

