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Pneumococcal Vaccines: Past Findings, Present Work, and Future Strategies [PDF]
Vaccines, 2021 The importance of Streptococcus pneumoniae has been well established. These bacteria can colonize infants and adults without symptoms, but in some cases can spread, invade other tissues and cause disease with high morbidity and mortality. The development
Giuliana S. Oliveira +3 more
doaj +2 more sources
Uptake of Pneumococcal Vaccines Among U.S. Adults After 2022 Update to Recommendations [PDF]
AJPM FocusIntroduction: Updated recommendations for adult pneumococcal vaccination in the U.S. (publication date: January 27, 2022) incorporated 2 new vaccines (15- and 20-valent pneumococcal conjugate vaccines), removed 13-valent pneumococcal conjugate vaccine ...
Ahuva Averin, MPP +5 more
doaj +2 more sources
Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]
, 2013 Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Chan, Jacqueline +10 more
core +27 more sources
Bacterium-like Particles from Corynebacterium pseudodiphtheriticum as Mucosal Adjuvant for the Development of Pneumococcal Vaccines [PDF]
VaccinesPreviously, it was shown that intranasally (i.n.) administered Corynebacterium pseudodiphtheriticum 090104 (Cp) or CP-derived bacterium-like particles (BLPs) improve the immunogenicity of the pneumococcal conjugate vaccine (PCV).
Ramiro Ortiz Moyano +10 more
doaj +2 more sources
Биопрепараты: Профилактика, диагностика, лечение, 2021 Streptococcus pneumoniae infection is the most common cause of high morbidity and mortality among children under 5 years of age, immunocompromised people, and the elderly.
M. V. Savkina +6 more
doaj +1 more source
Recent progress in pneumococcal protein vaccines
Frontiers in Immunology, 2023 Pneumococcal infections continue to pose a significant global health concern, necessitating the development of effective vaccines. Despite the progress shown by pneumococcal polysaccharide and conjugate vaccines, their limited coverage and the emergence ...
Sha Li +4 more
doaj +1 more source
Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection
Vaccines, 2020 Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million deaths annually, especially in young children and the elderly. To date, at least 98 different pneumococcal capsular serotypes have been identified. Currently, the vaccines
Malihe Masomian +3 more
doaj +1 more source
F1000Research, 2023 Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi +4 more
doaj +1 more source
Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]
Korean Journal of Pediatrics, 2014 The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
doaj +1 more source
Pneumococcal Choline-Binding Proteins Involved in Virulence as Vaccine Candidates
Vaccines, 2021 Streptococcus pneumoniae is a pathogen responsible for millions of deaths worldwide. Currently, the available vaccines for the prevention of S.
Julio Sempere +5 more
doaj +1 more source