Results 21 to 30 of about 45,004 (157)

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

open access: yes, 2009
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A   +8 more
core   +1 more source

The Significance of Subperiosteal Abscess Volume in Acute Mastoiditis

open access: yesThe Laryngoscope, EarlyView.
Both needle aspiration and I&D are safe methods to reduce the infective and inflammatory load of subperiosteal abscess due to acute mastoiditis and provide pus for culture. Higher volumes (~3 cm3 and more) should be managed initially with cortical mastoidectomy since the risk of no improvement following needle aspiration or I&D is higher.
Rani Abu‐Eta   +5 more
wiley   +1 more source

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

open access: yes, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds   +62 more
core   +3 more sources

A Vaccine Against Group B Streptococcus: Recent Advances [PDF]

open access: yes, 2020
Group B streptococcus (GBS) causes a high burden of neonatal and infant disease globally. Implementing a vaccine for pregnant women is a promising strategy to prevent neonatal and infant GBS disease and has been identified as a priority by the World ...
Carreras-Abad, C   +3 more
core   +2 more sources

Long‐Term Outcomes of Adult Temporal Bone Fractures With Hearing Loss: Results of a Multinational Database Analysis

open access: yesThe Laryngoscope, EarlyView.
This study uses a large multinational database to examine long‐term outcomes of adult temporal bone fractures. The risk for meningitis, labyrinthitis, facial nerve disorders, and cerebrospinal fluid leaks was elevated after fracture. Cochlear implantation was also more likely after temporal bone fracture.
Jason L. Steele   +7 more
wiley   +1 more source

Treatment strategy for systemic lupus erythematosus using belimumab as indicated by multi‐omics analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio   +5 more
wiley   +1 more source

Shingles & Pneumococcal Vaccines: Recommendations for Older Adults [PDF]

open access: yes, 2018
As the immune system tends to weaken over time, patients aged 50+ begin having increased risk for certain potentially preventable diseases, especially shingles and pneumonia.
Flinn, Benjamin
core   +1 more source

Beyond good intentions: lessons on equipment donation from an African hospital. [PDF]

open access: yes, 2008
OBJECTIVE: In 2000, a referral hospital in the Gambia accepted a donation of oxygen concentrators to help maintain oxygen supplies. The concentrators broke down and were put into storage.
Adegbola, Richard A   +7 more
core   +2 more sources

Weakened Airway Epithelial Junctions and Enhanced Neutrophil Elastase Release Contribute to Age‐Dependent Bacteremia Risk Following Pneumococcal Pneumonia

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
During spread of Streptococcus pneumoniae from the lung to the bloodstream, the pneumococcal pore‐forming toxin pneumolysin (PLY) disrupts apical junction complexes (AJCs) and triggers the transmigration of polymorphonuclear leukocytes (PMNs), which secrete tissue‐destructive neutrophil elastase.
Shuying Xu   +4 more
wiley   +1 more source

Improving Pneumococcal Vaccination Rates in Jefferson Hospital Ambulatory Practice Patients [PDF]

open access: yes, 2017
AIM: To improve the pneumococcal vaccination initiation rates in patients 65 years and older in Jefferson Hospital Ambulatory Practice (JHAP) to the institutional quality measure goal of 80% over a 4 month period from January to May of 2017.https://jdc ...
Enriquez, MD, Matthew   +3 more
core   +1 more source

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