Results 31 to 40 of about 622,361 (248)

Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens

Vaccines, 2019
Non-serotype-specific protein-based pneumococcal vaccines have received extensive research focus due to the limitations of polysaccharide-based vaccines.
Theano Lagousi, Paraskevi Basdeki, J. Routsias, V. Spoulou   +3 more
semanticscholar   +1 more source

Efficacy and Effectiveness of the PCV-10 and PCV-13 Vaccines Against Invasive Pneumococcal Disease

Pediatrics, 2020
Two PCVs are licensed for prevention of pneumococcal disease. Uncertainty about the effectiveness against AOM and serotype 19A invasive disease in children ≤5 years remains.
Melissa Berman-Rosa, Shauna O’Donnell, Mackenzie Barker, C. Quach   +3 more
semanticscholar   +1 more source

A Review of Pneumococcal Vaccines: Current Polysaccharide Vaccine Recommendations and Future Protein Antigens.

The Journal of Pediatric Pharmacology and Therapeutics, 2016
This review describes development of currently available pneumococcal vaccines, provides summary tables of current pneumococcal vaccine recommendations in children and adults, and describes new potential vaccine antigens in the pipeline.
Calvin C. Daniels, P. D. Rogers, Chasity M Shelton   +2 more
semanticscholar   +1 more source

Pneumococcal Polysaccharide Conjugated Vaccines and the Problem of Changing Circulating Serotypes of Pneumococcus

Эпидемиология и вакцинопрофилактика, 2023
Relevance. In 2007, WHO recommended pneumococcal conjugate vaccines (PCV) be included in national immunization schedules for young children. By 2020, 145 countries, including Russia, were using PCV. Aims.
N. N. Kostyukova, V. A. Bekhalo
doaj   +1 more source

Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease.

Cochrane Database of Systematic Reviews, 2017
BACKGROUND People with chronic obstructive pulmonary disease (COPD) are at increased risk of pneumococcal disease, especially pneumonia, as well as acute exacerbations with associated morbidity and healthcare costs. OBJECTIVES To determine the efficacy
J. Walters, Joanne Ngie Qing Tang, P. Poole, R. Wood‐Baker   +3 more
semanticscholar   +1 more source

Pneumococcal Vaccines

Indian Journal of Medical Microbiology, 2018
Streptococcus pneumoniae continues to take a heavy toll on childhood mortality and morbidity across the developing world. An estimated 10.6 million invasive pneumococcal diseases (IPDs) occur every year, with nearly 1 million deaths in children under 5 years of age. Introduction of vaccines in the childhood immunisation programme in developed world has
Anand, Manoharan, Ranjith, Jayaraman
openaire   +2 more sources

The remarkable history of pneumococcal vaccination: an ongoing challenge

Pneumonia, 2022
Although it varies with age and geographical distribution, the global burden of infection with Streptococcus pneumoniae (pneumococcus) remains considerable.
Daniel M. Musher, Ronald Anderson, Charles Feldman   +2 more
doaj   +1 more source

Effectiveness of pneumococcal vaccines in preventing pneumonia in adults, a systematic review and meta-analyses of observational studies

PLoS ONE, 2017
Introduction S. pneumoniae can cause a wide spectrum of diseases, including invasive pneumococcal disease and pneumonia. Two types of pneumococcal vaccines are indicated for use in adults: 23-valent pneumococcal polysaccharide vaccines (PPV23) and a 13 ...
M. Tin Tin Htar, Anke L. Stuurman, Germano Ferreira, C. Alicino, K. Bollaerts, C. Paganino, Ralf-Rene Reinert, Heinz-Josef Schmitt, C. Trucchi, T. Vestraeten, Filippo Ansaldi   +10 more
semanticscholar   +1 more source

CLINICAL AND IMMUNOLOGICAL EFFECT OF PNEUMOCOCCAL CONJUGATED VACCINES IN IMMUNOCOMPROMISED PATIENTS

Педиатрическая фармакология, 2010
Invasive pneumococcal infection is the most frequent cause of death in patients with immunodeficiences. The antibiotics used previously for prevention purposes are not efficient enough due to the developing antibiotic resistance.
A.A. Tarasova, M.P. Kostinov
doaj   +2 more sources

Immunogenicity and impact on disease activity of influenza and pneumococcal vaccines in systemic lupus erythematosus: a systematic literature review and meta-analysis.

Rheumatology, 2016
OBJECTIVES The aim was to assess the immunogenicity and the impact on disease activity of pneumococcal and influenza vaccines in SLE patients. METHODS We conducted a systematic literature review and meta-analysis of studies comparing the humoral ...
M. Puges, P. Biscay, T. Barnetche, M. Truchetet, C. Richez, J. Seneschal, N. Gensous, E. Lazaro, P. Duffau   +8 more
semanticscholar   +1 more source