Results 51 to 60 of about 45,004 (157)

Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy

Transplant Infectious Disease, EarlyView.
ABSTRACT Vaccine adjuvants are essential for enhancing immune responses to vaccines, particularly in immunocompromised populations who typically demonstrate suboptimal responses to standard vaccination. This narrative review evaluates the safety and efficacy of approved and candidate adjuvants in immunocompromised hosts, with emphasis on solid organ ...
Haya Hayek, Lana Hasan, Justin Z. Amarin, Yasmeen Z. Qwaider, Olla Hamdan, Wanderson Rezende, Kevin C. Dee, James D. Chappell, Natasha B. Halasa   +8 more
wiley   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Pediatric Post‐Vaccine Aluminum Granuloma: Morin Stain as a Diagnostic Aid

Journal of Cutaneous Pathology, Volume 52, Issue 6, Page 399-402, June 2025.
Justin R. Chang, Alvin Wong, Julio A. Diaz‐Perez, Chunyu Cai, Mark C. Mochel   +4 more
wiley   +1 more source

Impairment of Innate Immunity and Depletion of Vaccine‐Induced Memory B and T Cells in the Absence of the Spleen

American Journal of Hematology, Volume 100, Issue 5, Page 770-784, May 2025.
ABSTRACT Splenectomy or congenital asplenia is associated with severe reduction of memory B cells and increased risk of fulminant sepsis by encapsulated bacteria. Current guidelines recommend vaccinations against these pathogens before or after splenectomy, but the longevity of immunity acquired after splenectomy has not been determined.
Veronica Bordoni, Bianca Laura Cinicola, Eva Piano Mortari, Concetta Castilletti, Federica Guarracino, Christian Albano, Silvia Accordini, Anwar Baban, Antonio Di Sabatino, Carlo Maria Rossi, Marco Vincenzo Lenti, Anna Maria Zicari, Riccardo Cirelli, Marco Spada, Gian Luca Forni, Isabella Quinti, Mattia Algeri, Maddalena Casale, Silverio Perrotta, Franco Locatelli, Chiara Agrati, Rita Carsetti   +21 more
wiley   +1 more source

Immunizations - Not Just for Kids [PDF]

, 2007
Immunizations/vaccinations are beneficial for most people of all ages. Yet the mistaken belief persists that, with the exception of the flu vaccine, children should be the primary recipients of this important area of primary disease prevention.
Harrison G. Bloom
core  

Pneumococcic Vaccine In Pneumonia [PDF]

The American Journal of the Medical Sciences, 1909
n ...
openaire   +1 more source

Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. [PDF]

, 2008
BACKGROUND: The study describes the molecular epidemiology of Streptococcus pneumoniae causing invasive disease in Gambian children METHODS: One hundred and thirty-two S. pneumoniae isolates were recovered from children aged 2-29 months during the course
Adegbola, Richard A, Antonio, Martin, Awine, Tim, Biney, Ekow, Cutts, Felicity, Dada-Adegbola, Hannah, Enwere, Godwin, Greenwood, Brian M, O'Callaghan, John, Okoko, Brown, Oluwalana, Claire, Pfluger, Valentin, Pluschke, Gerd, Vaughan, Adeola, Zaman, Syed Ma   +14 more
core   +2 more sources

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]

, 2011
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith, Aspa, Austrian, Avery, Blake, Cecil, Chris Robertson, David Greenhalgh, Diggle, Donald Inverarity, Giles F. S. Edwards, Guimbao Bescós, Huss, Inostroza, Jim McMenamin, Johanna M. C. Jefferies, Karen Lamb, Kendrick, Lamb, Martin, Mathew Diggle, Shapiro, Stuart C. Clarke, Tim J. Mitchell, Weiss   +24 more
core   +3 more sources

Phase I, randomized, observer-blind, placebo-controlled studies to evaluate the safety, reactogenicity and immunogenicity of an investigational non-typeable Haemophilus influenzae (NTHi) protein vaccine in adults [PDF]

, 2016
Background: Non-typeable Haemophilus influenzae (NTHi) is a major cause of various respiratory diseases. The development of an effective vaccine against NTHi mandates new approaches beyond conjugated vaccines as this opportunistic bacterium is non ...
Aris, Emmanuel, Caubet, Magalie, Devaster, Jeanne-Marie, Haazen, Wouter, Leroux-Roels, Geert, Peeters, Mathieu, Shakib, Sepehr, Van Damme, Pierre   +7 more
core   +2 more sources

The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]

, 2014
The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER, Brooks, Brown, Buse, Chaudhuri, Clarke, Cooper Ramo, Drezner, Elbe, Fleury, Gold, Knight, Levy, Meyer, Petryna, Ramamurti, Roemer-Mahler, Schoofs, Wells, Whyte, Williams, Williamson, Youde, Zimmerman   +23 more
core   +1 more source