Results 51 to 60 of about 622,361 (248)

Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved]

F1000Research, 2023
Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi, Delan Ikram, Haider N. Dawood, Ali H. Al-Jumaili, Ali Al-Jabban   +4 more
doaj  

Long‐Term Outcomes of Adult Temporal Bone Fractures With Hearing Loss: Results of a Multinational Database Analysis

The Laryngoscope, EarlyView.
This study uses a large multinational database to examine long‐term outcomes of adult temporal bone fractures. The risk for meningitis, labyrinthitis, facial nerve disorders, and cerebrospinal fluid leaks was elevated after fracture. Cochlear implantation was also more likely after temporal bone fracture.
Jason L. Steele, Heather J. Smith, Samira Takkoush, Jumah G. Ahmad, Zachary D. Urdang, Neil S. Patel, Richard K. Gurgel, Mana Espahbodi   +7 more
wiley   +1 more source

ERA OF CONJUGATE VACCINES: INTERNATIONAL EXPERIENCE OF SUCCESSFUL APPLICATION

Педиатрическая фармакология, 2008
The article highlights comparative characteristics of the polysaccharide and conjugate vaccines against pneumococcal infection, meningococcosis and haemophilus influenza. The author stresses the advantage of the conjugate vaccines.
M.V. Fedoseenko, M.G. Galitskaya, L.S. Namazova   +2 more
doaj   +2 more sources

Environmental factors which can affect the burden of pneumococcal disease and the immune response to pneumococcal vaccines: the need for more precisely delineated vaccine recommendations

Expert Review of Vaccines, 2019
Introduction: Precision medicine describes the customization of healthcare tailored to the individual patient. Generally, vaccines are considered as public health tools rather than from the individual patient perspective.
Seong-Beom Park, Hyun-Jin Kim, Hee-Jin Cheong   +2 more
doaj   +1 more source

Otitis Media Trial Publication After ClinicalTrials.gov Registration

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the proportion of completed otitis media (OM) clinical trials registered on ClinicalTrials.gov and identify factors associated with nonpublication. Study Design Cross‐sectional observational study. Setting ClinicalTrials.gov registry and peer‐reviewed literature databases.
Michael Oca, Suraj M. Rajan, Z. Jason Qian   +2 more
wiley   +1 more source

Relationship between immune response to pneumococcal conjugate vaccines in infants and indirect protection after vaccine implementation

Expert Review of Vaccines, 2019
Introduction: Streptococcus pneumoniae is a leading cause of morbidity and mortality worldwide. Widespread infant vaccination with pneumococcal conjugate vaccines (PCVs) substantially reduced vaccine-serotype pneumococcal disease by direct protection of ...
R. Dagan
semanticscholar   +1 more source

Emerging vaccine strategies against the incessant pneumococcal disease

npj Vaccines, 2023
The incidence of invasive pneumococcal disease (IPD) caused by infection with the pathogen Streptococcus pneumoniae ( Spn ) has been on a downward trend for decades due to worldwide vaccination programs.
J. A. Duke, F. Avci
semanticscholar   +1 more source

Pre‐Vaccination Immunotypes and Immune Entropy Are Indicators of Multiple Vaccine Responsiveness

Aging Cell, EarlyView.
Pre‐vaccination immune profiles and a novel biomarker, immune entropy, are associated with responsiveness to influenza, pneumococcal, and SARS‐CoV‐2 vaccines, independent of age, sex, and CMV serostatus, and also correlate with inflammaging‐related serum proteins, supporting their potential as indicators of immunosenescence validated across diverse ...
Alper Cevirgel, Marieke van der Heiden, Sudarshan A. Shetty, Markus Viljanen, Martijn Vos, Elske Bijvank, Yannick van Sleen, Celine Imhof, Joeri A. J. Rolwes, Leonard Daniël Samson, Lisa Beckers, Nynke Rots, Josine van Beek, Anne‐Marie Buisman, Debbie van Baarle   +14 more
wiley   +1 more source

Redefining risk categories for pneumococcal disease in adults: critical analysis of the evidence

International Journal of Infectious Diseases, 2015
Objective: To analyze the available published data (2005–2014) describing the prevalence of multimorbidity in adult patients with pneumococcal disease, with a focus on the comorbidities considered by the Advisory Committee on Immunization Practices (ACIP)
Daniel Curcio, Alejandro Cané, Raúl Isturiz   +2 more
doaj   +1 more source

Cost-Effectiveness of 20-Valent Pneumococcal Conjugate Vaccine Among US Children with Underlying Medical Conditions

Infectious Diseases and Therapy
Introduction A 20-valent pneumococcal conjugate vaccine (PCV20) was recently recommended for use among US children. We evaluated the cost-effectiveness of PCV20 among children aged 6 years with chronic medical conditions (CMC+) and children aged 6 years ...
Mark H. Rozenbaum, Erica Chilson, Raymond Farkouh, Liping Huang, Alejandro Cane, Adriano Arguedas, Maria J. Tort, Vincenza Snow, Ahuva Averin, Derek Weycker, Dhwani Hariharan, Mark Atwood   +11 more
doaj   +1 more source