Results 91 to 100 of about 49,378 (316)

Serological immunity against vaccine‐preventable diseases in children with inflammatory bowel disease at diagnosis

JPGN Reports, EarlyView.
Abstract Objectives Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine‐preventable diseases. However, vaccination coverage in this population is often suboptimal. This retrospective study assessed the vaccination status and vaccine serology of children diagnosed with IBD in a high‐income country with broad vaccine access ...
Clara Noble, Renato Gualtieri, Klara Posfay‐Barbe, Nathalie Rock, Geraldine Blanchard‐Rohner   +4 more
wiley   +1 more source

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]

, 2012
The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M, Bentley, SD, Bootsma, HJ, Gould, KA, Hanage, WP, Hermans, PW, Hinds, J, Lambertsen, L, O'Brien, KL, Salter, SJ, Turner, P   +10 more
core   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

The regulation of the AdcR regulon in Streptococcus pneumoniae depends both on Zn2+- and Ni2+ -availability

Frontiers in Cellular and Infection Microbiology, 2015
By using a transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+.
Irfan eManzoor, Irfan eManzoor, Sulman eShafeeq, Sulman eShafeeq, Muhammad eAfzal, Muhammad eAfzal, Oscar P. Kuipers   +6 more
doaj   +1 more source

Epithelial cell–derived secreted and transmembrane 1a signals to activated neutrophils during pneumococcal pneumonia [PDF]

, 2016
Airway epithelial cell responses are critical to the outcome of lung infection. In this study, we aimed to identify unique contributions of epithelial cells during lung infection.
Belkina, Anna C., Deng, Jane C., Gower, Adam C., Jones, Matthew R., Kamata, Hirofumi, Lung, Wing Yi, Mizgerd, Joseph P., Quinton, Lee J., Ramirez, Maria I., Wasserman, Gregory A., Yamamoto, Kazuko, Yuen, Constance K., Zabinski, Mary C.   +12 more
core   +1 more source

The Political Economy of Patent Buyouts

The RAND Journal of Economics, EarlyView.
ABSTRACT Incentivizing innovation through buyouts may alleviate the social costs associated with patent power, but the political economy and feasibility of this potentially important financing mechanism have been understudied. We study an international setting of countries with different innovation and financing capabilities, and where financing ...
Amal Ahmad, Dominik Naeher, Sebastian Vollmer   +2 more
wiley   +1 more source

ACTIVE AND PASSIVE IMMUNITY TO PNEUMOCOCCUS INFECTION INDUCED IN RABBITS BY IMMUNIZATION WITH R PNEUMOCOCCI

Journal of Experimental Medicine, 1928
1. Rabbits, vaccinated by repeated intravenous injections of suspensions of heat-killed R pneumococci, acquire a marked degree of active immunity to infection with the virulent S forms of Pneumococcus Types I and II.
W. Tillett
semanticscholar   +1 more source

An outbreak of pneumococcal meningitis among older children (≥5 years) and adults after the implementation of an infant vaccination programme with the 13-valent pneumococcal conjugate vaccine in Ghana. [PDF]

, 2016
BACKGROUND: An outbreak of pneumococcal meningitis among non-infant children and adults occurred in the Brong-Ahafo region of Ghana between December 2015 and April 2016 despite the recent nationwide implementation of a vaccination programme for infants ...
Afreh, Osei Kuffour, Amponsa-Achiano, Kwame, Antonio, Martin, Appiah-Denkyira, Ebenezer, Asiedu-Bekoe, Franklin, Bampoe, Victor, Bannerman, Richard, D'Alessandro, Umberto, Ebruke, Chinelo, Foster-Nyarko, Ebenezer, Kaluwa, Owen, Kay, Gemma, Kuma, George Khumalo, Kwambana-Adams, Brenda Anna, Letsa, Timothy, Mwenda, Jason M, Ohene, Sally-Ann, Okoi, Catherine, Okot, Charles, Opare, David, Otu, Jacob Kweku, Owusu-Okyere, Godfred, Pallen, Mark J, Sarkodie, Badu, Senghore, Madikay, Worwui, Archibald Kwame, Zaman, Syed MA   +26 more
core   +2 more sources

Personalized Cancer Vaccines in the Clinical Trial Pipeline

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

ANAPHYLAXIS WITH THE TYPE-SPECIFIC CARBOHYDRATES OF PNEUMOCOCCUS

Journal of Experimental Medicine, 1929
1. The type-specific carbohydrates (haptens) of Pneumococcus Types I, II and III, when isolated in protein-free form, are devoid of the property of inducing active anaphylactic sensitization in guinea pigs. 2. The bacterial carbohydrates of Pneumococcus,
O. Avery, W. Tillett
semanticscholar   +1 more source