Results 101 to 110 of about 46,661 (280)

Conquering the pneumococcal nemesis with oral antibiotics

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2020
Introduction Streptococcus pneumoniae endocarditis (SPE) occurs in
Rana Garris   +7 more
doaj   +1 more source

ANAPHYLAXIS WITH THE TYPE-SPECIFIC CARBOHYDRATES OF PNEUMOCOCCUS

open access: yesJournal of Experimental Medicine, 1929
1. The type-specific carbohydrates (haptens) of Pneumococcus Types I, II and III, when isolated in protein-free form, are devoid of the property of inducing active anaphylactic sensitization in guinea pigs. 2. The bacterial carbohydrates of Pneumococcus,
O. Avery, W. Tillett
semanticscholar   +1 more source

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz   +17 more
wiley   +1 more source

In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]

open access: yes, 2019
An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D.   +8 more
core   +1 more source

EXPERIMENTAL STUDIES ON PNEUMOCOCCUS INFECTIONS

open access: yesJournal of Experimental Medicine, 1909
1. Phagocytosis of pneumococci in vitro runs parallel with phagocytosis in vivo. 2. Virulence depends not only on resistance to phagocytosis, but also on the ability to grow in the body of the animal. 3.
S. Strouse
semanticscholar   +1 more source

HIV‐1 viral load and reservoir size remain stable following SARS‐CoV‐2 mRNA vaccination in people with HIV

open access: yesHIV Medicine, EarlyView.
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri   +8 more
wiley   +1 more source

Isolation site influences virulence phenotype of serotype 14 Streptococcus pneumoniae strains belonging to multilocus sequence type 15 [PDF]

open access: yes, 2015
Streptococcus pneumoniae is a diverse species causing invasive as well as localized infections that result in massive global morbidity and mortality. Strains vary markedly in pathogenic potential, but the molecular basis is obscured by the diversity and ...
Amin, Zarina   +6 more
core   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Investigation into the Causes and Severity of the 1918 Influenza Pandemic [PDF]

open access: yes, 2018
The 1918 Influenza outbreak is regarded as one of the worst pandemics in human history due to its widespread effects across the globe and its high death rate.
Freedenberg, Alex T.
core   +1 more source

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