Results 51 to 60 of about 49,296 (330)
SEROTYPE-INDEPENDENT VACCINES AGAINST PNEUMOCOCCAL INFECTION
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Creation of serotype-independent vaccines includes 4 directions - construction of protein vaccines based on recombinant pneumococcus proteins, whole-cell killed or attenuated vaccines, DNA-vaccines and use of Streptococcus pneumoniae as a carrier for ...
I. B. Semenova, N. A. Mikhailova
doaj +1 more source
Детские инфекции (Москва), 2020 Objective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent
I. N. Protasova +6 more
doaj +1 more source
The pneumococcal response to oxidative stress includes a role for Rgg [PDF]
, 2009 Streptococcus pneumoniae resides in the oxygen-rich environment of the upper respiratory tract, and therefore the ability to survive in the presence of oxygen is an important aspect of its in vivo survival. To investigate how S.
Andrew, PW +4 more
core +3 more sources
THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS
Journal of Experimental Medicine, 1923 1. A method is given for the concentration and purification of the soluble specific substance of the pneumococcus. 2. The material obtained by this method is shown to consist mainly of a carbohydrate which appears to be a polysaccharide built up of ...
M. Heidelberger, W. F. Goebel, O. Avery
semanticscholar +1 more source
IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF PNEUMOCOCCUS
Journal of Experimental Medicine, 1923 In the preceding communication, it has been pointed out that the so-called soluble specific substance of pneumococcus is nonprotein in nature, and in its present state of purification is either itself a polysaccharide, or intimately associated with the ...
O. Avery, Michael Heidelberger
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung [PDF]
, 2014 The pneumococcus is the world's foremost respiratory pathogen, but the mechanisms allowing this pathogen to proceed from initial asymptomatic colonization to invasive disease are poorly understood.
Harvey, Richard M. +3 more
core +1 more source
THE ELABORATION OF SPECIFIC SOLUBLE SUBSTANCE BY PNEUMOCOCCUS DURING GROWTH
Journal of Experimental Medicine, 1917 1. A specifically reacting substance of bacterial origin is present in the cell-free fluids of young cultures of pneumococcus. This substance is present when the organisms are growing at their maximum rate and undergoing little or no cell death, and ...
A. R. Dochez, O. Avery
semanticscholar +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source