Results 31 to 40 of about 46,661 (280)

The development of a 16S rRNA gene based PCR for the identification of Streptococcus pneumoniae and comparison with four other species specific PCR assays [PDF]

, 2010
Background: Streptococcus pneumoniae is one of the most frequently encountered pathogens in humans but its differentiation from closely related but less pathogenic streptococci remains a challenge.
Nabil Abdullah El Aila, Stefan Emler, Tarja Kaijalainen, Thierry De Baere, Bart Saerens, Elife Alkan, Pieter Deschaght, Rita Verhelst, Mario Vaneechoutte, A Ortqvist, L Spanjaard, D Rozkiewicz, JC Arbique, CA Dias, S Nunes, SI Aguiar, T Kaijalainen, N Suzuki, TO Messmer, R Verhelst, T Kaijalainen, G Carvalho Mda, GM Abdeldaim, M Vaneechoutte, S Rintamaki, KE Morrison, D Llull, JC McAvin, N Suzuki, ER Keith, RW Bentley   +30 more
core   +3 more sources

The manufacture of antibodies in vitro [PDF]

, 1942
A protein solution with the properties of a specific antiserum to the triphenylmethane dye methyl blue has been made by treating a solution of bovine gamma-globulin and the dye with alkali and then slowly neutralizing the alkali.
Campbell, Dan H., Pauling, Linus
core   +2 more sources

Pneumococcus nasopharyngeal carriage in children attending an academic hospital in Pretoria, South Africa, after the introduction of pneumococcal vaccine

Southern African Journal of Infectious Diseases, 2019
Background: In 2009, pneumococcal conjugate vaccine was introduced in South Africa. However, there are concerns that this could lead to an increase in colonisation of non-vaccine serotypes (serotype replacement). Methods: In a cross-sectional study, 350
Charity Newton, Harry Maake, Caroline Maluleka, Siyazi Mda   +3 more
doaj   +1 more source

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]

, 2012
The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M, Bentley, SD, Bootsma, HJ, Gould, KA, Hanage, WP, Hermans, PW, Hinds, J, Lambertsen, L, O'Brien, KL, Salter, SJ, Turner, P   +10 more
core   +1 more source

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]

, 2020
We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM, Hinds, J, Hossain, I, Hua, Y, Mackenzie, GA, Manna, S, Mulholland, EK, Ndiaye, M, Ortika, BD, Salaudeen, R, Satzke, C   +10 more
core   +4 more sources

Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life

Frontiers in Immunology, 2021
BackgroundDevelopment of vaccines to prevent disease and death from Streptococcus pneumoniae, and nontypeable Haemophilus influenzae (NTHi), the main pathogens that cause otitis media, pneumonia, meningitis and sepsis, are a global priority.
Kelly M. Martinovich, Tasmina Rahman, Tasmina Rahman, Camilla de Gier, Camilla de Gier, Elke J. Seppanen, Tilda Orami, Caitlyn M. Granland, Jacinta Francis, Mition Yoannes, Karli J. Corscadden, Rebecca Ford, Peter Jacoby, Anita H. J. van den Biggelaar, Anita H. J. van den Biggelaar, Lauren O. Bakaletz, Allan W. Cripps, Deborah Lehmann, Deborah Lehmann, Peter C. Richmond, Peter C. Richmond, William S. Pomat, William S. Pomat, Lea-Ann S. Kirkham, Lea-Ann S. Kirkham, Ruth B. Thornton, Ruth B. Thornton   +26 more
doaj   +1 more source

Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens

PLoS Pathogens, 2017
Naturally acquired immunity against invasive pneumococcal disease (IPD) is thought to be dependent on anti-capsular antibody. However nasopharyngeal colonisation by Streptococcus pneumoniae also induces antibody to protein antigens that could be ...
R. Wilson, J. Cohen, Mark Reglinski, R. José, W. Chan, H. Marshall, C. D. de Vogel, S. Gordon, D. Goldblatt, F. Petersen, H. Baxendale, Jeremy S. Brown   +11 more
semanticscholar   +1 more source

Deoxyribonucleases of Pneumococcus

Journal of Biological Chemistry, 1967
Abstract Two enzymes with deoxyribonuclease activity were isolated from Pneumococcus. One of these, an endonuclease active on both native and denatured deoxyribonucleic acid, produced 5'-phosphate-terminated fragments which, even after extensive degradation, were larger than mononucleotides.
S, Lacks, B, Greenberg
openaire   +2 more sources

Epithelial cell–derived secreted and transmembrane 1a signals to activated neutrophils during pneumococcal pneumonia [PDF]

, 2016
Airway epithelial cell responses are critical to the outcome of lung infection. In this study, we aimed to identify unique contributions of epithelial cells during lung infection.
Belkina, Anna C., Deng, Jane C., Gower, Adam C., Jones, Matthew R., Kamata, Hirofumi, Lung, Wing Yi, Mizgerd, Joseph P., Quinton, Lee J., Ramirez, Maria I., Wasserman, Gregory A., Yamamoto, Kazuko, Yuen, Constance K., Zabinski, Mary C.   +12 more
core   +1 more source

Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]

, 2012
WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black, Catto, Choudhuri, George, Graham, Higginson, Horwood, Huda, Lawn, Nair, Nair, Nair, O'Brien, Osterholt, Rudan, Rudan, Rudan, Rudan, Rudan, Tomlinson, Watt, Webster   +21 more
core   +3 more sources