Results 11 to 20 of about 46,661 (280)

PM2.5 impairs macrophage functions to exacerbate pneumococcus-induced pulmonary pathogenesis

open access: yesParticle and Fibre Toxicology, 2020
Background Pneumococcus is one of the most common human airway pathogens that causes life-threatening infections. Ambient fine particulate matter (PM) with aerodynamic diameter ≤ 2.5 μm (PM2.5) is known to significantly contribute to respiratory diseases.
Yu-Wen Chen   +11 more
doaj   +2 more sources

Platelets, Bacterial Adhesins and the Pneumococcus

open access: yesCells, 2022
Systemic infections with pathogenic or facultative pathogenic bacteria are associated with activation and aggregation of platelets leading to thrombocytopenia and activation of the clotting system.
Kristin Jahn   +4 more
semanticscholar   +1 more source

Mechanisms Underlying Pneumococcal Transmission and Factors Influencing Host-Pneumococcus Interaction: A Review

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Streptococcus pneumoniae (also called pneumococcus) is not only a commensal that frequently colonizes the human upper respiratory tract but also a pathogen that causes pneumonia, sepsis, and meningitis.
Ayumi Morimura   +3 more
semanticscholar   +1 more source

Fine Particulate Matter Exposure Alters Pulmonary Microbiota Composition and Aggravates Pneumococcus-Induced Lung Pathogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2020
Exposure to fine particulate matter (PM) with aerodynamic diameter ≤2.5 μm (PM2.5) is closely correlated with respiratory diseases. Microbiota plays a key role in maintaining body homeostasis including regulation of host immune status and metabolism.
Yu-wen Chen   +9 more
semanticscholar   +1 more source

Hepatitis B Virus, Pneumococcal, Diphtheria, and Tetanus Vaccination Responses in Compensated Cirrhosis. [PDF]

open access: yesLiver Int
ABSTRACT Background and Aims Cirrhosis favours infections that can lead to liver decompensation and death. Some of these infections can be prevented by vaccination. This study aimed to evaluate the immune response after HBV, pneumococcal, diphtheria, and tetanus vaccination in cirrhotic patients.
Haghnejad V   +10 more
europepmc   +2 more sources

Mechanisms and impact of genetic recombination in the evolution of Streptococcus pneumoniae

open access: yesComputational and Structural Biotechnology Journal, 2015
Streptococcus pneumoniae (the pneumococcus) is a highly recombinogenic bacterium responsible for a high burden of human disease globally. Genetic recombination, a process in which exogenous DNA is acquired and incorporated into its genome, is a key ...
Chrispin Chaguza   +2 more
doaj   +1 more source

Evolving Understanding of the Causes of Pneumonia in Adults, With Special Attention to the Role of Pneumococcus

open access: yesClinical Infectious Diseases, 2017
Understanding of the microbiology of pneumonia has evolved. The role of pneumococcus has greatly declined. “Atypical” agents cause only a very small proportion of cases. Viruses are prominent.
D. Musher, M. Abers, J. Bartlett
semanticscholar   +1 more source

Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function

open access: yesBMC Infectious Diseases, 2011
Background Influenza virus is a major cause of respiratory disease worldwide and Streptococcus pneumoniae infection associated with influenza often leads to severe complications.
Tu Wenwei   +6 more
doaj   +1 more source

Influence of Obesity on Pneumococcus Infection Risk in the Elderly

open access: yesFrontiers in Endocrinology, 2019
Obesity negatively affects immune function and host defense mechanisms. Obesity is associated with chronic activation of the innate immune system and consequent local and systemic inflammation which contribute to pathologic conditions such as type-2 ...
D. Frasca, J. Mcelhaney
semanticscholar   +1 more source

PROPERTIES OF NATIVE PROTEIN-CONTAINING ANTIGENS OF STREPTOCOCCUS PNEUMONIAE

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. The study of immunochemical and immunobiological properties of native protein-containing antigens of pneumococcus. Materials and methods. The study was carried out on the strains of the Collective Usage Center «Collection of Mechnikov Res. Inst. for
D. S. Vorobyev   +5 more
doaj   +1 more source

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