Journal of Experimental Medicine, 1914 Solutions of the bodies of pneumococci, obtained by dissolving them in dilute solutions of sodium cholate, by permitting them to undergo autolysis, or by first freezing, drying, and then grinding in salt solution, are actively hemolytic for rabbit, sheep, guinea pig, and human red blood corpuscles. The substance on which this hemolytic property depends
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The interrelationship between phagocytosis, autophagy and formation of neutrophil extracellular traps following infection of human neutrophils by Streptococcus pneumoniae [PDF]
, 2017 Neutrophils play an important role in the innate immune response to infection with Streptococcus pneumoniae, the pneumococcus. Pneumococci are phagocytosed by neutrophils and undergo killing after ingestion.
Evans, Tom J. +2 more
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Unraveling the seasonal epidemiology of pneumococcus
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The pneumococcus, a bacterium frequently carried in the nasopharynx, is responsible for a wide spectrum of infections in humans, including severe invasive pneumococcal diseases (IPDs). In nontropical climates, IPDs typically display a marked
M. Domenech de Cellès +7 more
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IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]
, 2018 Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K. +4 more
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Selective pressure: Rise of the nonencapsulated pneumococcus
PLoS Pathogens, 2019 Introduction Streptococcus pneumoniae (pneumococcus) remains the leading cause of bacterial otitis media (OM), pneumonia, and meningitis despite routine vaccination spanning decades [1,2].
J. Bradshaw, L. McDaniel
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Phosphatidylcholine (lecithin) stimulating effect on pathogenic properties of pneumococcus
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014 The authors have studied the effect of phosphatidylcholine (lecithin) - a derivative of choline - on the biological properties of streptococus pneumonia.
A. S. Kvetnaya, L. I. Zhelezova
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Overlapping functionality of the Pht proteins in zinc homeostasis of streptococcus pneumoniae [PDF]
, 2014 Streptococcus pneumoniae is a globally significant pathogen that causes a range of diseases, including pneumonia, sepsis, meningitis, and otitis media. Its ability to cause disease depends upon the acquisition of nutrients from its environment, including
Eijkelkamp, Bart A. +5 more
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SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS
Journal of Experimental Medicine, 1930 1. Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pneumococci (Fraction C). Following crisis the reaction is no longer demonstrable. 2.
W. Tillett, T. Francis
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Variation of growth characteristics of pneumococcus with environmental conditions
BMC Microbiology, 2019 Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood.
A. Tóthpál +4 more
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Vaccines to Prevent Meningitis: Historical Perspectives and Future Directions
Microorganisms, 2021 Despite advances in the development and introduction of vaccines against the major bacterial causes of meningitis, the disease and its long-term after-effects remain a problem globally.
Mark R. Alderson +5 more
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