Results 51 to 60 of about 46,661 (280)

A stochastic differential equation SIS epidemic model [PDF]

, 2011
In this paper we extend the classical susceptible-infected-susceptible epidemic model from a deterministic framework to a stochastic one and formulate it as a stochastic differential equation (SDE) for the number of infectious individuals $I(t)$. We then
Gray, Alison, Greenhalgh, David, Hu, L., Mao, Xuerong, Pan, Jiafeng   +4 more
core   +1 more source

Epidemiology, virulence factors and management of the pneumococcus

F1000Research, 2016
Pneumococcal infections continue to cause significant morbidity and mortality in patients throughout the world. This microorganism remains the most common bacterial cause of community-acquired pneumonia and is associated with a considerable burden of ...
C. Feldman, R. Anderson
semanticscholar   +1 more source

PNEUMOCOCCUS PERITONITIS [PDF]

Annals of Surgery, 1918
  +8 more sources

Vaccinal Prevention of Pneumococcal Infection in Children

Педиатрическая фармакология, 2015
It is known that before vaccination had been widely introduced pneumococcal infection was the cause of death of more than 1.5 mn people around the world annually, 40% of whom were infants.
A. A. Baranov, L. S. Namazova-Baranova, N. I. Briko, Y. V. Lobzin, V. K. Tatochenko, S. M. Kharit, M. V. Fedoseyenko, E. A. Vishnyova, L. R. Selimzyanova   +8 more
doaj   +1 more source

Pneumococcal genetic variability in age-dependent bacterial carriage

eLife, 2022
The characteristics of pneumococcal carriage vary between infants and adults. Host immune factors have been shown to contribute to these age-specific differences, but the role of pathogen sequence variation is currently less well-known. Identification of
Philip HC Kremer, Bart Ferwerda, Hester J Bootsma, Nienke Y Rots, Alienke J Wijmenga-Monsuur, Elisabeth AM Sanders, Krzysztof Trzciński, Anne L Wyllie, Paul Turner, Arie van der Ende, Matthijs C Brouwer, Stephen D Bentley, Diederik van de Beek, John A Lees   +13 more
doaj   +1 more source

Combination of Cefditoren and N-acetyl-l-Cysteine Shows a Synergistic Effect against Multidrug-Resistant Streptococcus pneumoniae Biofilms

Microbiology Spectrum, 2022
Biofilm formation by Streptococcus pneumoniae is associated with colonization of the upper respiratory tract, including the carrier state, and with chronic respiratory infections in patients suffering from chronic obstructive pulmonary disease (COPD ...
Mirella Llamosí, Julio Sempere, Pilar Coronel, Mercedes Gimeno, Jose Yuste, Mirian Domenech   +5 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Vaccinations and Immune Response in Celiac Disease

Vaccines, 2020
Immune response to vaccinations in celiac patients is of growing scientific interest. However, some aspects of the relationship between celiac disease (CD) and vaccines are still unclear.
Stefano Passanisi, Valeria Dipasquale, Claudio Romano   +2 more
doaj   +1 more source

THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS

Journal of Experimental Medicine, 1923
1. A method is given for the concentration and purification of the soluble specific substance of the pneumococcus. 2. The material obtained by this method is shown to consist mainly of a carbohydrate which appears to be a polysaccharide built up of ...
M. Heidelberger, W. F. Goebel, O. Avery
semanticscholar   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

American Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini   +38 more
wiley   +1 more source