Results 11 to 20 of about 91,224 (305)

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection

Frontiers in Microbiology, 2021
T cell responses play critical roles in host adaptive immunity against Pneumocystis. However, the dynamics and diversity of the T cell immune repertoire in human immunodeficiency virus (HIV)-negative Pneumocystis pneumonia (PCP) remains unclear.
Hu-Qin Yang, Yi-Shan Wang, Kan Zhai, Zhao-Hui Tong   +3 more
doaj   +2 more sources

Clinical and translational research in Pneumocystis and Pneumocystis pneumonia* [PDF]

Parasite, 2011
Pneumocystis pneumonia (PcP) remains a significant cause of morbidity and mortality in immunocompromised persons, especially those with human immunodeficiency virus (HIV) infection.
Huang L.
doaj   +5 more sources

Transcriptomic and Proteomic Approaches to Finding Novel Diagnostic and Immunogenic Candidates in Pneumocystis

mSphere, 2019
Pneumocystis pneumonia is the most common serious opportunistic infection in patients with HIV/AIDS. Furthermore, Pneumocystis pneumonia is a feared complication of the immunosuppressive drug regimens used to treat autoimmunity, malignancy, and ...
Taylor Eddens, Waleed Elsegeiny, David Ricks, Meagan Goodwin, William T. Horne, Mingquan Zheng, Jay K. Kolls   +6 more
doaj   +2 more sources

Intrinsic Programming of Alveolar Macrophages for Protective Antifungal Innate Immunity Against Pneumocystis Infection

Frontiers in Immunology, 2018
Invasive fungal infections, including Pneumocystis Pneumonia (PcP), remain frequent life-threatening conditions of patients with adaptive immune defects.
Samir P. Bhagwat, Francis Gigliotti, Francis Gigliotti, Jing Wang, Zhengdong Wang, Robert H. Notter, Patrick S. Murphy, Fátima Rivera-Escalera, Jane Malone, Michael B. Jordan, Michael R. Elliott, Michael R. Elliott, Terry W. Wright, Terry W. Wright   +13 more
doaj   +2 more sources

Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

BMC Infectious Diseases, 2019
Background Pneumocystis jirovecii pneumonia (PCP) is one of the most common HIV-related opportunistic infections. The diagnosis of PCP is based on analyses from respiratory tract specimens which may require the invasive procedure of a diagnostic ...
Helena Hammarström, Anna Grankvist, Isabell Broman, Nahid Kondori, Christine Wennerås, Magnus Gisslen, Vanda Friman   +6 more
doaj   +2 more sources

Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis

mBio, 2018
Pneumocystis species are opportunistic mammalian pathogens that cause severe pneumonia in immunocompromised individuals. These fungi are highly host specific and uncultivable in vitro.
Ousmane H. Cissé, Liang Ma, Da Wei Huang, Pavel P. Khil, John P. Dekker, Geetha Kutty, Lisa Bishop, Yueqin Liu, Xilong Deng, Philippe M. Hauser, Marco Pagni, Vanessa Hirsch, Richard A. Lempicki, Jason E. Stajich, Christina A. Cuomo, Joseph A. Kovacs   +15 more
doaj   +2 more sources

Persistence of Pneumocystis [PDF]

Chest, 1985
Walter T. Hughes
openalex   +4 more sources

Pneumocystis jiroveci Pneumonia: A Review of Management in Human Immunodeficiency Virus (HIV) and Non-HIV Immunocompromised Patients

Avicenna Journal of Medicine, 2023
Pneumocystis jirovecii pneumonia is an opportunistic fungal infection that was mainly associated with pneumonia in patients with advanced human immunodeficiency virus (HIV) disease.
Atif Ibrahim, Asmi Chattaraj, Qamar Iqbal, A. Anjum, M. Rehman, Zobia Aijaz, Fazila Nasir, Sadia Ansar, T. Zangeneh, Ahmad Iftikhar   +9 more
semanticscholar   +1 more source

The Pathogenesis and Diagnosis of Pneumocystis jiroveci Pneumonia

Journal of Fungi, 2022
Pneumocystis jiroveci remains an important fungal pathogen in immunocompromised hosts. The environmental reservoir remains unknown. Pneumonia (PJP) results from airborne transmission, including in nosocomial clusters, or with reactivation after an ...
A. Apostolopoulou, J. Fishman
semanticscholar   +1 more source

Pneumocystis jirovecii Disease: Basis for the Revised EORTC/MSGERC Invasive Fungal Disease Definitions in Individuals Without Human Immunodeficiency Virus.

Clinical Infectious Diseases, 2021
BACKGROUND Pneumocystis jirovecii pneumonia (PCP) causes substantive morbidity in immunocompromised patients. The EORTC/MSGERC convened an expert group to elaborate consensus definitions for Pneumocystis disease for the purpose of interventional clinical
K. Lagrou, S. Chen, H. Masur, C. Viscoli, C. Decker, L. Pagano, A. Groll   +6 more
semanticscholar   +1 more source