Results 41 to 50 of about 32,245 (181)

Metabolomic Profiling of Lungs from Mice Reveals the Variability of Metabolites in Pneumocystis Infection and the Metabolic Abnormalities in BAFF-R-Deficient Mice

Journal of Inflammation Research, 2023
Heng-Mo Rong,* Han-Yu-Jie Kang,* Zhao-Hui Tong Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China ...
Rong HM, Kang HYJ, Tong ZH
doaj  

Pediatric Clostridiodes difficile infection with toxic megacolon successfully treated with fecal microbiota transplantation

JPGN Reports, EarlyView.
Abstract The rising incidence of pediatric Clostridioides difficile infection (CDI), particularly in medically complex patients, calls for novel, individualized treatments. While fecal microbiota transplantation (FMT) is well‐described for recurrent CDI, this report describes the first pediatric case of fulminant CDI with toxic megacolon successfully ...
Dana McCarney, Pamela Chen, Jenna Simes, Stacy A. Kahn   +3 more
wiley   +1 more source

CONVENTIONAL METHODS FOR THE DIAGNOSIS OF PNEUMOCYSTIS JIROVECII IN IMMUNOCOMPROMISED IRAQI PATIENTS

The Iraqi Journal of Medical Sciences, 2016
Background: Pneumocystis jirovecii is the causative agent of pneumocystis pneumonia, one of the most frequent and severe opportunistic infections in immunocompromised patients.
Isa S. Touhali, Azhar A.F. Ibrahim, Haider N. Dawood   +2 more
doaj   +6 more sources

What do Pneumocystis organisms tell us about the phylogeography of their hosts? The case of the woodmouse Apodemus sylvaticus in continental Europe and western Mediterranean islands.

PLoS ONE, 2015
Pneumocystis fungi represent a highly diversified biological group with numerous species, which display a strong host-specificity suggesting a long co-speciation process.
Christine Demanche, Manjula Deville, Johan Michaux, Véronique Barriel, Claire Pinçon, Cécile Marie Aliouat-Denis, Muriel Pottier, Christophe Noël, Eric Viscogliosi, El Moukhtar Aliouat, El Moukhtar Aliouat, Eduardo Dei-Cas, Serge Morand, Jacques Guillot   +13 more
doaj   +1 more source

Ecosystem retrogression enhances cross‐domain microbial stability and increases the genetic potential for nutrient cycling

mLife, EarlyView.
Abstract Ecosystem retrogression drives nutrient depletion, reduced productivity, and profound reorganization of soil microbial communities. Using amplicon sequencing and genome‐resolved metagenomics, we examined how cross‐domain microbial networks and functional gene potential respond to long‐term phosphorus and nitrogen limitation along the well ...
Javier A. Ceja‐Navarro, Dishant Patel, Garret Genco, Alyssa Byer, Daliang Ning, Kenneth H. Wan, Susan E. Celniker, Jizhong Zhou, Paul Dijkstra, Bruce A. Hungate, Jennifer Pett‐Ridge, Eoin L. Brodie   +11 more
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Pneumocystis jirovecii pneumonia in non-HIV patients: need for a more extended prophylaxis

Frontiers in Medicine
BackgroundPneumocystis jirovecii pneumonia (PCP) has a significant mortality rate for non-HIV immunocompromised patients. Prevention is primarily based on combined trimethoprim and sulfamethoxazole (TMP-SMX) but guidelines on pneumocystosis prophylaxis ...
Léo Sauvat, Laure Denis, Céline Nourrisson, Philippe Poirier, Marc Ruivard, Guillaume Le Guenno   +5 more
doaj   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, EarlyView.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source