Results 61 to 70 of about 32,245 (181)

Infection Incidence and Survival in Patients With Multiple Myeloma and Chronic Lymphocytic Leukaemia: A Growing Concern in the Era of Modern Therapies

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Patients with multiple myeloma (MM) and chronic lymphocytic leukaemia (CLL) are burdened by immunodeficiency due to treatment and underlying disease. Infection‐related mortality remains a significant concern for patients' overall survival (OS). Methods This Swedish, population‐based study examined incidence of infections and OS in
Ingrid Glimelius, Love Tätting, Jonatan Freilich, M. Natalia Stelmaszuk, Qian Yang, Anna Deleskog, Sigurður Y. Kristinsson   +6 more
wiley   +1 more source

Diagnosis of the primary infection by pneumocystis in autopsy specimens from two infants using lung impression smears (touch preps)

Medical Mycology Case Reports, 2014
The primary infection by Pneumocystis of normal, healthy infants is asymptomatic and goes undiagnosed. Microscopy diagnosis of Pneumocystis was sought in lung impression smears (LIS) from two ~3-month-old infants dying unexpectedly in the community ...
Carolina A. Ponce, Rebeca I. Bustamante, Myriam Gallo, Sergio L. Vargas   +3 more
doaj   +1 more source

Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis

mBio, 2018
Pneumocystis species are opportunistic mammalian pathogens that cause severe pneumonia in immunocompromised individuals. These fungi are highly host specific and uncultivable in vitro.
Ousmane H. Cissé, Liang Ma, Da Wei Huang, Pavel P. Khil, John P. Dekker, Geetha Kutty, Lisa Bishop, Yueqin Liu, Xilong Deng, Philippe M. Hauser, Marco Pagni, Vanessa Hirsch, Richard A. Lempicki, Jason E. Stajich, Christina A. Cuomo, Joseph A. Kovacs   +15 more
doaj   +1 more source

SARS‐CoV‐2 mRNA Vaccination Induces Neutralizing Antibodies and Type I IFN Changes in People Living With HIV

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT This study examined changes in anti‐Spike (anti‐S) antibodies (Abs) and type I interferon (IFN‐I) following the BNT162b2 vaccine in people living with HIV (PLWH) and analyzed the impact of demographic and immunological factors. In total, 75 PLWH and 28 healthy donors were followed at baseline (T0), at the second dose (T1), after the second ...
Federica Frasca, Luca Maddaloni, Alessandra D'Auria, Matteo Fracella, Ginevra Bugani, Carmen Falvino, Valentina Baccolini, Giuseppe Migliara, Francesca Aloisi, Letizia Santinelli, Enrico Palermo, Luca Bortolani, Alessandro Lazzaro, Giancarlo Ceccarelli, Ombretta Turriziani, Claudio Maria Mastroianni, Guido Antonelli, Gabriella d'Ettorre, Carolina Scagnolari   +18 more
wiley   +1 more source

Nosocomial Pneumocystis jirovecii infections

Parasite, 2008
Airborne transmission of Pneumocystis sp. from host to host has been demonstrated in rodent models and several observations suggest that interindividual transmission occurs in humans.
Nevez G., Chabé M., Rabodonirina M., Virmaux M., Dei-Cas E., Hauser P.M., Totet A.   +6 more
doaj   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Palivizumab for Donor‐Derived RSV Infection in an Adult Bilateral Lung Transplant Recipient: A Case Report

Respirology Case Reports, Volume 14, Issue 8, August 2026.
We describe the use of off‐label palivizumab in an early post‐operative bilateral lung transplant recipient with probable donor‐derived RSV who developed persistent severe LRTI and respiratory failure. RSV PCR Ct fell and remained low from day 0 to day 42 despite conventional therapy until palivizumab was administered on day 44, following which we ...
Rosemary Meharry, Cassandra Vale, John Mackintosh   +2 more
wiley   +1 more source

Pneumocystis Infection in Pregnant Women: A Scoping Review

Journal of Fungi
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during pregnancy
Irene Calderón-Baturone, Rocío Salsoso, Elena Charpentier, Yaxsier de Armas, Pilar Guadix, Rubén Morilla, Enrique J. Calderón, Vicente Friaza   +7 more
doaj   +1 more source

Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages

BMC Microbiology, 2010
Background Pneumocystis pneumonia is a common opportunistic disease in AIDS patients. The alveolar macrophage is an important effector cell in the clearance of Pneumocystis organisms by phagocytosis.
Liao Chung-Ping, Xuei Xiaoling, Liu Yunlong, Cheng Bi-Hua, Lu Debao, Lasbury Mark E, Durant Pamela J, Lee Chao-Hung   +7 more
doaj   +1 more source

ctDNA Detection of Polyclonal KRAS Resistance in Adagrasib‐Treated NSCLC

Thoracic Cancer, Volume 17, Issue 15, August 2026.
Longitudinal ctDNA monitoring by ddPCR and targeted NGS in an adagrasib‐treated KRASG12C mutant NSCLC patient revealed the emergence of three new KRAS mutations (G12D, G13D, Q61H), indicating polyclonal resistance, approximately 10 weeks before any radiologic progression by RECIST 1.1.
Marion Caumeil, Julie A. Vendrell, Simon Cabello‐Aguilar, Sarah Cavaillon, Quentin Dominique Thomas, Jérôme Solassol   +5 more
wiley   +1 more source