Results 81 to 90 of about 42,547 (218)

The Power of Hematopoietic Stem Cell Transplantation (HSCT): A Curative Approach for Diffuse Large B‐Cell Lymphoma (DLBCL) Incidentally Detected in a SCID Baby

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Lymphoma is a rare complication of X‐linked severe combined immunodeficiency (X‐SCID) caused by IL2RG deficiency. We report an infant with IL2RG‐SCID who developed diffuse large B‐cell lymphoma (DLBCL) during pretransplant evaluation. A male infant with T−B+ SCID was diagnosed at 1 month of age and referred for hematopoietic stem cell ...
Burcu Sarıgül Cimi, Sule Haskologlu, Candan Islamoglu, Gokcan Ozturk, Nazlı Deveci, Hasret Erkmen, Selin Sevinc, Can Akal, Seda Kaynak Sahap, Sonay Özdemir, Suat Fitoz, Isınsu Kuzu, Emel Unal, Nurdan Tacyıldız, Figen Dogu, Aydan Ikinciogullari   +15 more
wiley   +1 more source

Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis

mBio, 2018
Pneumocystis species are opportunistic mammalian pathogens that cause severe pneumonia in immunocompromised individuals. These fungi are highly host specific and uncultivable in vitro.
Ousmane H. Cissé, Liang Ma, Da Wei Huang, Pavel P. Khil, John P. Dekker, Geetha Kutty, Lisa Bishop, Yueqin Liu, Xilong Deng, Philippe M. Hauser, Marco Pagni, Vanessa Hirsch, Richard A. Lempicki, Jason E. Stajich, Christina A. Cuomo, Joseph A. Kovacs   +15 more
doaj   +1 more source

Cytomegalovirus in Bronchoalveolar Lavage Fluid: A Predictor of Outcome in Immunocompromised Patients

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Cytomegalovirus (CMV) is a prevalent herpesvirus that remains typically asymptomatic in immunocompetent individuals but can cause severe, potentially life‐threatening disease in immunocompromised patients. This study assessed the impact of CMV‐associated lower respiratory tract infections (LRTIs), diagnosed by polymerase chain reaction (PCR ...
Theodora Zouvani, Meropi Karakioulaki, Kathleen Jahn, Sebastian Fähndrich, Björn C. Frye, Leticia Grize, Eleni Papakonstantinou, Hartmut Hengel, Karoline Leuzinger, Hans H. Hirsch, Daiana Stolz   +10 more
wiley   +1 more source

All‐Oral PI3Kδ and HDAC Inhibition with Parsaclisib Plus Chidamide and Step‐Down Maintenance in Relapsed or Refractory Peripheral T‐Cell Lymphoma: A Phase Ib Trial

MedComm, Volume 7, Issue 10, October 2026.
ABSTRACT Single‐agent targeted therapies for relapsed or refractory peripheral T‐cell lymphoma (R/R peripheral T‐cell lymphoma [PTCL]) produce modest, short‐lived responses, underscoring the need for tolerable, chemotherapy‐free combinations. In an open‐label, single‐arm Phase Ib trial at two tertiary hospitals, we evaluated parsaclisib plus chidamide ...
Xufeng Luo, Zheng Yan, Wei Fang, Hanchi Duan, Qiuyu Zhang, Haiying Wang, Shuna Yao, Jiuyang Zhang, Yiping Jin, Wenyong Li, Xiaolu Teng, Lina Zhang, Lijie Liang, Quande Lin, Ping Wang, Haoran Si, Jinxin Miao, Wenping Zhou, Zhihua Yao, You‐Wen He, Qingxin Xia, Yanyan Liu   +21 more
wiley   +1 more source

Pneumocystis carinii -prevalenssi kaatopaikan rottapopulaatiossa

, 2003
Pneumocystis carinii kuuluu sieniin muodostaen hyvin heterogeenisen ja isäntälajispesifisen ryhmän. Organismin eri tyyppejä tavataan ihmisillä ja useilla eri eläinlajeilla. P.
Dillard, Kati
core  

Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions [PDF]

, 2010
Jose G Castro1, Maya Morrison-Bryant21Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA; 2Jackson Memorial Hospital/University of Miami Infectious Diseases Fellowship Program, Miami, Florida, USAAbstract:
null Morrison-Bryant, Morrison-Bryant, Maya, Jose Castro, Jose G Castro, Maya Morrison-Bryant, Castro, Jose G   +5 more
core   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Human Immmunodeficiency Virus Infection Related Pneumocystis Jiroveci Pneumonia and Suicide: An Autopsy Case Report

, 2016
Pneumocystis jiroveci is the most common and serious opportunistic infection in acquired immune deficiency syndrome patients. It is detected in approximately 80% of human immunodeficiency virus (HIV) infected individuals. In this paper, we present a case
Muzaffer Yıldırım, Taner Daş, Aytül Sargan, Ahmet Selçuk Gürler, Gülhan Yağmur, Cumhur Selçuk Topal, Murat Nihat Arslan, Gökhan Umut, Hızır Aslıyüksek   +8 more
core   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

Bruton's Tyrosine Kinase Inhibitors: Mechanisms, Efficacy, Toxicities and Applications for the Treatment of Human Diseases

MedComm, Volume 7, Issue 10, October 2026.
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley   +1 more source