Results 71 to 80 of about 32,245 (181)

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

BMC Infectious Diseases, 2019
Background Pneumocystis jirovecii pneumonia (PCP) is one of the most common HIV-related opportunistic infections. The diagnosis of PCP is based on analyses from respiratory tract specimens which may require the invasive procedure of a diagnostic ...
Helena Hammarström, Anna Grankvist, Isabell Broman, Nahid Kondori, Christine Wennerås, Magnus Gisslen, Vanda Friman   +6 more
doaj   +1 more source

Risk of urinary tract infection with SGLT2 inhibitor initiation in patients with immune‐mediated inflammatory diseases and type 2 diabetes: A target trial emulation using a Japanese hospital‐based claims database

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1310-1321, August 2026.
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima, Nobuyuki Yajima, Takashi Nomiyama, Ryoko Sakai, Hisashi Noma, Akira Katagiri, Naoto Tamura   +6 more
wiley   +1 more source

Niflumic Acid Reverses Airway Mucus Excess and Improves Survival in the Rat Model of Steroid-Induced Pneumocystis Pneumonia

Frontiers in Microbiology, 2019
Although the role of adaptive immunity in fighting Pneumocystis infection is well known, the role of the innate, airway epithelium, responses remains largely unexplored.
Francisco J. Pérez, Pablo A. Iturra, Carolina A. Ponce, Fabien Magne, Víctor Garcia-Angulo, Sergio L. Vargas   +5 more
doaj   +1 more source

Candida oesophagitis as an Initial Manifestation of VEXAS Syndrome: Expanding Evidence for an Acquired Immunodeficiency Phenotype

eJHaem, Volume 7, Issue 4, August 2026.
Demi Rianne Vintges, Marina Weerheim, Faiz Karim   +2 more
wiley   +1 more source

Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways.

PLoS ONE, 2019
Clara cells are the main airway secretory cells able to regenerate epithelium in the distal airways through transdifferentiating into goblet cells, a process under negative regulation of the Notch pathway.
Andrea Méndez, Diego A Rojas, Carolina A Ponce, Rebeca Bustamante, Caroll J Beltrán, Jorge Toledo, Victor A García-Angulo, Mauricio Henriquez, Sergio L Vargas   +8 more
doaj   +1 more source

Pneumocystis jiroveci (formerly Pneumocystis carinii) [PDF]

American Journal of Transplantation, 2004
openaire   +2 more sources

Reply to Liu et al., “Inability To Culture Pneumocystis jirovecii”

mBio, 2018
Verena Schildgen, Oliver Schildgen
doaj   +1 more source

Pneumocystis pneumonia.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000
No Abstract.
openaire   +2 more sources

Pneumocystis Infections

Medical Mycology Journal, 2012
Takahiro, Aoki, Shinichi, Oka
openaire   +3 more sources