Results 21 to 30 of about 91,224 (305)
Cold Spring Harbor Perspectives in Medicine, 2014 Since its initial misidentification as a trypanosome some 100 years ago, Pneumocystis has remained recalcitrant to study. Although we have learned much, we still do not have definitive answers to such basic questions as, where is the reservoir of infection, how does Pneumocystis reproduce, what is the mechanism of infection, and are there true species ...
Francis, Gigliotti +2 more
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Genomic insights into the host specific adaptation of the Pneumocystis genus
Communications Biology, 2021 Pneumocystis jirovecii , the fungal agent of human Pneumocystis pneumonia, is closely related to macaque Pneumocystis . Little is known about other Pneumocystis species in distantly related mammals, none of which are capable of establishing infection in ...
O. Cissé +24 more
semanticscholar +1 more source
Inability to Culture
mBio, 2018 In their 2014 research article, Verena Schildgen et al. reported that Pneumocystis jirovecii can be successfully cultured and propagated from P. jirovecii-positive bronchoalveolar lavage (BAL) patient samples by using a permanent three-dimensional air ...
Yueqin Liu +2 more
doaj +2 more sources
Pneumocystis Pneumonia: Immunity, Vaccines, and Treatments
Pathogens, 2021 For individuals who are immunocompromised, the opportunistic fungal pathogen Pneumocystis jirovecii is capable of causing life-threatening pneumonia as the causative agent of Pneumocystis pneumonia (PCP). PCP remains an acquired immunodeficiency disease (
Aaron D. Gingerich, K. Norris, J. Mousa
semanticscholar +1 more source
S-Adenosylmethionine and Pneumocystis [PDF]
FEMS Microbiology Letters, 2004 Pneumocystis is a parasitic fungus causing pneumonia in immunosuppressed mammals and S-adenosylmethionine a key intermediary metabolite for all cells. Other than a species of Rickettsia bacteria and an aberrant strain of the protozoan Amoeba proteus, Pneumocystis is the only cell known unable to synthesize AdoMet; it must extract this key compound from
Allen B. Clarkson, Salim Merali
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Diagnosing Pneumocystis jirovecii pneumonia: A review of current methods and novel approaches.
Medical Mycology, 2020 Pneumocystis jirovecii can cause life-threatening pneumonia in immunocompromised patients. Traditional diagnostic testing has relied on staining and direct visualization of the life-forms in bronchoalveolar lavage fluid.
M. Bateman, R. Oladele, J. Kolls
semanticscholar +1 more source
Journal of the Formosan Medical Association, 2008 Pneumocystis pneumonia (PcP) in humans is caused by Pneumocystis jirovecii, which has recently been reclassified as a fungus because its cell wall composition and nucleotide sequences are more similar to those of fungi. PcP occurs only in immunocompromised individuals such as those with AIDS. Despite the use of highly active antiretroviral therapy, PcP
Jang-Jih Lu, Chao-Hung Lee
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A Case of COVID-19 and Pneumocystis jirovecii Coinfection
American Journal of Respiratory and Critical Care Medicine, 2020 Lymphocytopenia has been identified as a common laboratory finding in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, particularly among those with more severe presentations (1); however, there are limited data on ...
A. Menon +11 more
semanticscholar +1 more source
Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. [PDF]
, 2017 Pneumocystis jirovecii pneumonia (PCP) typically presents as an interstitial and alveolar process with ground glass opacities on chest computed tomography (CT).
Block, Brian L +6 more
core +3 more sources
Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia
Tuberculosis and Respiratory Diseases, 2020 In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia (PCP) is a wellk-nown opportunistic infection and its management has been established.
S. Tasaka
semanticscholar +1 more source