Results 21 to 30 of about 74,652 (269)

Predicting Species Boundaries and Assessing Undescribed Diversity in Pneumocystis, an Obligate Lung Symbiont

Journal of Fungi, 2022
Far more biodiversity exists in Fungi than has been described, or could be described in several lifetimes, given current rates of species discovery. Although this problem is widespread taxonomically, our knowledge of animal-associated fungi is especially
Spenser J. Babb-Biernacki, Jacob A. Esselstyn, Vinson P. Doyle   +2 more
doaj   +1 more source

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick, Chang, Emily G, Crothers, Kristina, Davis, J Lucian, Huang, Laurence, Hunt, Peter W, Kaswabuli, Sylvia, Lalitha, Rejani, Lederman, Michael M, Lin, Jue, Moisi, Daniela, Moore, Julia, Musisi, Emmanuel, Sanyu, Ingvar, Sessolo, Abdulwahab, Wang, Richard J, Worodria, William   +16 more
core   +2 more sources

Immunization with Pneumocystis recombinant KEX1 induces robust and durable humoral responses in immunocompromised non-human primates

Human Vaccines & Immunotherapeutics, 2019
Infection with the opportunistic fungal pathogen, Pneumocystis jirovecii causes life-threatening pneumonia in immunocompromised individuals. In addition to HIV-1 infected patients, individuals at risk of Pneumocystis infection include those receiving ...
Viviana Cobos Jiménez, Whitney Rabacal, Emily Rayens, Karen A. Norris   +3 more
doaj   +1 more source

Pneumocystis jirovecii infection [PDF]

Thorax, 2004
A review of Pneumocystis and the rationale for renaming it The organism Pneumocystis causes severe pneumonia in individuals with immune systems impaired by HIV, transplantation, malignancy, connective tissue disease, and the treatment thereof. In HIV infected patients it remains a major pathogen in those who are unaware of their HIV serostatus, or who
R, Miller, L, Huang
openaire   +2 more sources

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection

Frontiers in Microbiology, 2021
T cell responses play critical roles in host adaptive immunity against Pneumocystis. However, the dynamics and diversity of the T cell immune repertoire in human immunodeficiency virus (HIV)-negative Pneumocystis pneumonia (PCP) remains unclear.
Hu-Qin Yang, Yi-Shan Wang, Kan Zhai, Zhao-Hui Tong   +3 more
doaj   +1 more source

Intrinsic Programming of Alveolar Macrophages for Protective Antifungal Innate Immunity Against Pneumocystis Infection

Frontiers in Immunology, 2018
Invasive fungal infections, including Pneumocystis Pneumonia (PcP), remain frequent life-threatening conditions of patients with adaptive immune defects.
Samir P. Bhagwat, Francis Gigliotti, Francis Gigliotti, Jing Wang, Zhengdong Wang, Robert H. Notter, Patrick S. Murphy, Fátima Rivera-Escalera, Jane Malone, Michael B. Jordan, Michael R. Elliott, Michael R. Elliott, Terry W. Wright, Terry W. Wright   +13 more
doaj   +1 more source

Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance [PDF]

, 2004
Pneumocystis pneumonia (PCP) remains a major cause of illness and death in HIV-infected persons. Sulfa drugs, trimethoprim-sulfamethoxazole (TMP-SMX) and dapsone are mainstays of PCP treatment and prophylaxis.
Atzori, C, Benfield, T, Crothers, KA, Haung, L, Helweg-Larsen, J, Miller, R, Rabodonirina, M   +6 more
core   +2 more sources

DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of
T. N. Rybalkina, N. V. Karazhas, P. A. Savinkov, R. E. Boshyan, M. Yu. Lysenkova, M. N. Kornienko, E. M. Burmistrov, P. A. Veselovsky, I. A. Soldatova   +8 more
doaj   +1 more source

Detection of Pneumocystis and Morphological Description of Fungal Distribution and Severity of Infection in Thirty-Six Mammal Species

Journal of Fungi, 2023
Pneumocystis spp. are thought to adapt to the lungs of potentially all mammals. However, the full host range, fungal burden and severity of infection are unknown for many species.
Christiane Weissenbacher-Lang, Barbara Blasi, Patricia Bauer, Diana Binanti, Karin Bittermann, Lara Ergin, Carmen Högler, Tanja Högler, Magdalena Klier, Julia Matt, Nora Nedorost, Serenella Silvestri, Daniela Stixenberger, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Amélie Desvars-Larrive, Annika Posautz, Herbert Weissenböck   +18 more
doaj   +1 more source

Analysis of Pneumocystis Transcription Factor Evolution and Implications for Biology and Lifestyle

mBio, 2023
Pneumocystis jirovecii kills hundreds of thousands of immunocompromised patients each year. Yet many aspects of the biology of this obligate pathogen remain obscure because it is not possible to culture the fungus in vitro independently of its host ...
Ryan Ames, Alistair J. P. Brown, Ivana Gudelj, Olga A. Nev   +3 more
doaj   +1 more source