Results 31 to 40 of about 61,919 (199)

The Impact of HAART on the Respiratory Complications of HIV Infection: Longitudinal Trends in the MACS and WIHS Cohorts [PDF]

, 2013
Objective: To review the incidence of respiratory conditions and their effect on mortality in HIV-infected and uninfected individuals prior to and during the era of highly active antiretroviral therapy (HAART).
A Johannessen, A Lindberg, AK Chaturvedi, Alison Morris, AN Phillips, B Balbi, BR Celli, Charles R. Rinaldo, Christine B. Alden, DB Coultas, E Gouws, EA Engels, EC Seaberg, Eric C. Kleerup, Eric C. Seaberg, F Gutin, FJ Palella Jr, FN Engsig, G. K. Balasubramani, GA D’Jaen, GD Kirk, GM Allardice, GM Clifford, J Almirall, Jason F. Okulicz, JE Kaplan, JF Murray, JM Wallace, John Phair, Joseph B. Margolick, JR Grubb, K Crothers, K Crothers, K Crothers, K Sigel, L Dal Maso, Laurence Huang, Lawrence Kingsley, M Bower, M Frisch, M Herida, Matthew R. Gingo, MR Gingo, MR Gingo, MS Shiels, NA Hessol, Nancy A. Hessol, O Sitbon, PY Hsue, R McKenzie, RA Kaslow, RD Moore, RE Hirschtick, RM Phelps, Roger Detels, Ruth M. Greenblatt, S Hariri, Sarah H. Sutton, SB Foster, SE Barkan, Stephen R. Wisniewski, Susan Holman, T Takahashi, V Dufour   +63 more
core   +3 more sources

Intrinsic Programming of Alveolar Macrophages for Protective Antifungal Innate Immunity Against Pneumocystis Infection

Frontiers in Immunology, 2018
Invasive fungal infections, including Pneumocystis Pneumonia (PcP), remain frequent life-threatening conditions of patients with adaptive immune defects.
Samir P. Bhagwat, Francis Gigliotti, Francis Gigliotti, Jing Wang, Zhengdong Wang, Robert H. Notter, Patrick S. Murphy, Fátima Rivera-Escalera, Jane Malone, Michael B. Jordan, Michael R. Elliott, Michael R. Elliott, Terry W. Wright, Terry W. Wright   +13 more
doaj   +1 more source

Analysis of Pneumocystis Transcription Factor Evolution and Implications for Biology and Lifestyle

mBio, 2023
Pneumocystis jirovecii kills hundreds of thousands of immunocompromised patients each year. Yet many aspects of the biology of this obligate pathogen remain obscure because it is not possible to culture the fungus in vitro independently of its host ...
Ryan Ames, Alistair J. P. Brown, Ivana Gudelj, Olga A. Nev   +3 more
doaj   +1 more source

DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of
T. N. Rybalkina, N. V. Karazhas, P. A. Savinkov, R. E. Boshyan, M. Yu. Lysenkova, M. N. Kornienko, E. M. Burmistrov, P. A. Veselovsky, I. A. Soldatova   +8 more
doaj   +1 more source

Transcriptomic and Proteomic Approaches to Finding Novel Diagnostic and Immunogenic Candidates in Pneumocystis

mSphere, 2019
Pneumocystis pneumonia is the most common serious opportunistic infection in patients with HIV/AIDS. Furthermore, Pneumocystis pneumonia is a feared complication of the immunosuppressive drug regimens used to treat autoimmunity, malignancy, and ...
Taylor Eddens, Waleed Elsegeiny, David Ricks, Meagan Goodwin, William T. Horne, Mingquan Zheng, Jay K. Kolls   +6 more
doaj   +1 more source

Detection of Pneumocystis and Morphological Description of Fungal Distribution and Severity of Infection in Thirty-Six Mammal Species

Journal of Fungi, 2023
Pneumocystis spp. are thought to adapt to the lungs of potentially all mammals. However, the full host range, fungal burden and severity of infection are unknown for many species.
Christiane Weissenbacher-Lang, Barbara Blasi, Patricia Bauer, Diana Binanti, Karin Bittermann, Lara Ergin, Carmen Högler, Tanja Högler, Magdalena Klier, Julia Matt, Nora Nedorost, Serenella Silvestri, Daniela Stixenberger, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Amélie Desvars-Larrive, Annika Posautz, Herbert Weissenböck   +18 more
doaj   +1 more source

Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients [PDF]

, 2003
Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Ambrose, HE, Denis, CM, Lindley, AR, Miller, RF, Wakefield, AE   +4 more
core  

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia

Frontiers in Immunology, 2016
Pneumocystis pneumonia is a major cause of morbidity and mortality among immunocompromised patients, especially in the context of HIV/AIDS. In the murine model of Pneumocystis pneumonia, CD4+ T-cells are required for clearance of a primary infection of ...
Nicholas M de la Rua, Derrick Richard Samuelson, Tysheena P Charles, David Allen Welsh, Judd E. Shellito   +4 more
doaj   +1 more source

ANK1 and EPB41 Variants and The Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, Accepted Article.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source