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Analysis of Pneumocystis Transcription Factor Evolution and Implications for Biology and Lifestyle
Pneumocystis jirovecii kills hundreds of thousands of immunocompromised patients each year. Yet many aspects of the biology of this obligate pathogen remain obscure because it is not possible to culture the fungus in vitro independently of its host ...
Ryan Ames+3 more
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Pneumocystis jirovecii infection [PDF]
A review of Pneumocystis and the rationale for renaming it The organism Pneumocystis causes severe pneumonia in individuals with immune systems impaired by HIV, transplantation, malignancy, connective tissue disease, and the treatment thereof. In HIV infected patients it remains a major pathogen in those who are unaware of their HIV serostatus, or who
Laurence Huang, Robert F. Miller
openaire +3 more sources
The Fifth European Conference on Infections in Leukaemia (ECIL-5) convened a meeting to establish evidence-based recommendations for using tests to diagnose Pneumocystis jirovecii pneumonia (PCP) in adult patients with haematological malignancies ...
A. Alanio+12 more
semanticscholar +1 more source
Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. [PDF]
BACKGROUND: Invasive fungal diseases (IFDs) remain important causes of morbidity and mortality. The consensus definitions of the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group have ...
Akan, H+64 more
core +5 more sources
Pneumocystis Pneumonia (PCP) is a potentially life-threatening infection that can occur in individuals who are immunocompromised. In PCP steroid use is still recommended especially in patients with moderate and severe severity.
Resti Yudhawati, Whendy Wijaksono
doaj +1 more source
Pneumocystis spp. are thought to adapt to the lungs of potentially all mammals. However, the full host range, fungal burden and severity of infection are unknown for many species.
Christiane Weissenbacher-Lang+18 more
doaj +1 more source
Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology : a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologique (Grrr-OH) study [PDF]
Background: Acute respiratory failure (ARF) is the most frequent complication in patients with hematological malignancies and is associated with high morbidity and mortality.
Azoulay, Elie+19 more
core +2 more sources
Targeting β-glucans, vital components of the Pneumocystis cell wall
β-glucan is the most abundant polysaccharide in the cell wall of Pneumocystis jirovecii, which has attracted extensive attention because of its unique immunobiological characteristics.
Mengyan Wang+4 more
doaj +1 more source
Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa+3 more
core +1 more source
The 5th European Conference on Infections in Leukaemia (ECIL-5) meeting aimed to establish evidence-based recommendations for the prophylaxis of Pneumocystis jirovecii pneumonia (PCP) in non-HIV-infected patients with an underlying haematological ...
J. Maertens+12 more
semanticscholar +1 more source