Case Report: Successful treatment of severe pneumocystis carinii pneumonia in a case series of primary nephrotic syndrome after receiving anti-CD20 monoclonal antibody therapy [PDF]
Frontiers in Pediatrics, 2023 Rituximab is emerging as a new steroid sparing agent in children with difficult-to-treat nephrotic syndrome due to its ability of depleting CD20-positive B cells.
Lili Liu +8 more
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Immunization with Pneumocystis carinii A121–85 antigen activates immune function against P. carinii [PDF]
BMC Immunology, 2021 Background Pneumocystis pneumonia (PcP), which is caused by Pneumocystis carinii, is a life-threatening infection that affects immunocompromised individuals. Unfortunately, chemoprophylaxis and dapsone are only effective for half of the patients with PcP,
Tong Tong +3 more
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Extracellular vesicles from Pneumocystis carinii-infected rats impair fungal viability but are dispensable for macrophage functions [PDF]
Microbiology SpectrumPneumocystis spp. are host obligate fungal pathogens that can cause severe pneumonia in mammals and rely heavily on their host for essential nutrients. The lack of a sustainable in vitro culture system poses challenges in understanding their metabolism ...
Steven G. Sayson +2 more
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PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity [PDF]
, 2010 Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active ...
Jiri Gut +7 more
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Functional Characterization of
mBio, 2016 Fungi in the genus Pneumocystis live in the lungs of mammals, where they can cause a fatal pneumonia (PCP [Pneumocystis pneumonia]) in hosts with compromised immune systems.
Melanie T. Cushion +5 more
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Pneumocystis carinii Pneumonia in Renal-Transplant Recipients Treated with Cyclosporine and Steroids [PDF]
Journal of Infectious Diseases, 1984 Fourteen of 156 renal-transplant recipients treated with cyclosporine and steroids developed Pneumocystis carinii-related pneumonia (PCP) over a 19-month period.
A. M. Hardy +4 more
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Concurrent COVID-19 and pneumocystis carinii pneumonia in a patient subsequently found to have underlying hairy cell leukemia [PDF]
Radiology Case Reports, 2022 SARS-CoV-2 infection manifestation has great diversity and it becomes even greater while co-infection occurs or there is a serious underlying disease in an affected patient.
Vahan Moradians, MD +4 more
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Nested–polymerase chain reaction detection of f. sp. in a suspected immunocompromised Cavalier King Charles spaniel with multiple infections [PDF]
SAGE Open Medical Case Reports, 2019 A 7-month-old Cavalier King Charles Spaniel female was referred due to a chronic cough refractory to antibiotic treatments. Laboratory findings showed leukocytosis, increased serum C-reactive protein, hypogammaglobulinemia, and decreased total serum ...
Matteo Petini +3 more
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Comparative Genomics Suggests Primary Homothallism of
mBio, 2015 Pneumocystis species are fungal parasites of mammal lungs showing host specificity. Pneumocystis jirovecii colonizes humans and causes severe pneumonia in immunosuppressed individuals.
João M. G. C. F. Almeida +4 more
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Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis [PDF]
Antimicrobial Agents and Chemotherapy, 1984 Walter T. Hughes, B L Smith
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