Results 21 to 30 of about 10,727 (168)

Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

open access: yesEmerging Infectious Diseases, 2003
Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia.
Aimable Nahimana   +6 more
doaj   +1 more source

Comparative genomics suggests that the fungal pathogen pneumocystis is an obligate parasite scavenging amino acids from its host's lungs. [PDF]

open access: yesPLoS ONE, 2010
Pneumocystis jirovecii is a fungus causing severe pneumonia in immuno-compromised patients. Progress in understanding its pathogenicity and epidemiology has been hampered by the lack of a long-term in vitro culture method.
Philippe M Hauser   +6 more
doaj   +1 more source

Enfortumab vedotin plus pembrolizumab in treatment‐naïve metastatic urothelial carcinoma patients: An Austrian real‐world analysis

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1654-1665, 15 March 2026.
What's new? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke   +30 more
wiley   +1 more source

A retrospective case series of 66 foals with presumed acute interstitial pneumonia

open access: yesEquine Veterinary Education, Volume 38, Issue 3, Page 143-153, March 2026.
Summary Background There is limited literature describing acute interstitial pneumonia (AIP) in foals. Objectives Description of clinical and ultrasonographic findings in 66 foals affected by AIP. Investigation into whether the number of AIP cases is associated with specific climatic conditions. We also investigated whether clinical, haematological and
L. Weißlein, F. Freise, M. Venner
wiley   +1 more source

Aerosolised pentamidine for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome Aerosol de pentamidina no tratamento da pneumonia por Pneumocystis carinii em pacientes com a síndrome da imunodeficiência adquirida

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1990
The goal of this study was to evaluate inhaled pentamidine for the treatment of patients with mild and moderate Pneumocystis carinii pneumonitis. Eight adults with AIDS and pneumocystis pneumonia (4 with a first episode and 4 with a repeat pneumocystosis)
Adriana Weinberg   +5 more
doaj   +1 more source

Exploring microorganism–host interactions: Emerging organoid models and analytical approaches

open access: yesmLife, Volume 5, Issue 1, Page 17-34, February 2026.
Abstract Microorganisms play a vital role in human health through their interactions with the body. Studies of host–microbe mechanisms and interactions are crucial for advancing health management. Recently, the organoid‐based models have provided new platforms in this field.
Yue Shi   +6 more
wiley   +1 more source

Ploidy of cell-sorted trophic and cystic forms of Pneumocystis carinii.

open access: yesPLoS ONE, 2011
Once regarded as an AIDS-defining illness, Pneumocystis pneumonia (PcP) is nowadays prevailing in immunocompromised HIV-negative individuals such as patients receiving immunosuppressive therapies or affected by primary immunodeficiency.
Anna Martinez   +8 more
doaj   +1 more source

Vitamin D‐Mediated Hypercalcemia in a Dog With Putative Cutaneous Pythiosis

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT A 12‐month‐old dog was diagnosed with cutaneous pythiosis after presenting with a nonhealing metatarsal wound, an inguinal mass, and regional lymphadenopathy. Both cytology of the abnormal lymph nodes and histopathology of the inguinal mass showed granulomatous inflammation. ELISA serology was positive for Pythium insidiosum. The dog developed
Jennifer Brodkin   +3 more
wiley   +1 more source

Basic biology of Pneumocystis carinii: a mini review

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Basic aspects of cell biology of Pneumocystis carinii are reviewed with major emphasis on its life cycle and the structural organization of the trophozoites and cyst forms.
Wanderley de Souza, Marlene Benchimol
doaj   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

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