Results 61 to 70 of about 51,262 (290)

A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship

Emerging Infectious Diseases, 2002
The disease known as Pneumocystis carinii pneumonia (PCP) is a major cause of illness and death in persons with impaired immune systems. While the genus Pneumocystis has been known to science for nearly a century, understanding of its members remained ...
James R. Stringer, Charles B. Beard, Robert F. Miller, Ann E. Wakefield   +3 more
doaj   +1 more source

Isolation of the Pneumocystis carinii dihydrofolate synthase gene and functional complementation in Saccharomyces cerevisiae [PDF]

, 2017
The Pneumocystis carinii gene encoding the enzyme dihydrofolate synthase (DHFS), which is involved in the essential biosynthesis of folates, was isolated from clones of the Pneumocystis genome project, and sequenced. The deduced P.
Hauser, Philippe M., Macreadie, Ian G.
core  

Functional characterization of the Pneumocystis jirovecii potential drug targets dhfs and abz2 involved in folate biosynthesis. [PDF]

, 2015
Pneumocystis species are fungal parasites colonizing mammal lungs with strict host specificity. Pneumocystis jirovecii is the human-specific species and can turn into an opportunistic pathogen causing severe pneumonia in immunocompromised individuals ...
Cissé, O.H., Hauser, P.M., Luraschi, A., Monod, M., Pagni, M.   +4 more
core   +1 more source

Diagnosis of Granulomatosis With Polyangiitis in a 39‐Year‐Old Woman With a Recent History of Traveling to Malaria‐Endemic Region: A Case Report

Clinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT Granulomatosis with Polyangiitis (GPA) is a rare vasculitis that can complicate the diagnostic process, especially in patients with complex medical histories. This case report details a 39‐year‐old woman with situs inversus totalis, Kartagener syndrome, and hypothyroidism, who presented to the emergency department with intermittent petechiae ...
Hanie Forouzandeh, Ahmadreza Rajabi, Abbas Ali Torfeh Esfahani, Farzin Khorvash, Mansoor Karimifar   +4 more
wiley   +1 more source

Quantitative Economic Evaluations of HIV-Related Prevention and Treatment Services: A Review [PDF]

, 1994
Dr. Holtgrave and colleagues at the CDC set forth an extensive taxonomy of HIV prevention and treatment services and review reports of efforts to subject some of those services to formal economic evaluation.
Holtgrave, David R., Valdiserri, Ronald O., West, Gary A.   +2 more
core   +2 more sources

Cytokine profiles in bronchoalveolar lavage fluid and blood in HIV-seronegative patients with Pneumocystis carinii pneumonia [PDF]

, 1996
Contains fulltext : 23621___.pdf (publisher's version ) (Open ...
Beckers, P., Festen, J., Gallati, H., Hamersvelt, H.W. van, Meer, J.W.M. van der, Perenboom, R.M., Sauerwein, R., Schijndel, A.C.H. van   +7 more
core   +1 more source

S-Adenosylmethionine and Pneumocystis carinii [PDF]

Journal of Biological Chemistry, 2000
We previously reported that S-adenosylmethionine (AdoMet), a key molecule in methylation reactions and polyamine biosynthesis, enhances axenic culture of the AIDS-associated opportunistic fungal pathogen Pneumocystis carinii. Here we report that AdoMet is absolutely required for continuous growth. Two transporters are present, one high affinity, K(m) =
Salim Merali, Diana Vargas, Matthew C. Franklin, Allen B. Clarkson   +3 more
openaire   +3 more sources

A Case of Trimethoprim‐Sulfamethoxazole Associated Aseptic Meningitis

Clinical Case Reports, Volume 13, Issue 2, February 2025.
ABSTRACT Most cases of aseptic meningitis, or nonsuppurative meningitis, are caused by viruses or systemic diseases. Nonetheless, drug‐induced aseptic meningitis should be considered in the differential diagnosis, particularly with the recent use of antibiotics and nonsteroidal anti‐inflammatory drugs.
Malik W. Z. Khan, Abdul Moeez, Sameen Farooq, Adam Saeed, Salma Qudrat, Farishta Ali, Faheemullah Khan   +6 more
wiley   +1 more source

Persistent Lymphopenia as a Poor Prognostic Factor in Patients With Multiple Organ Dysfunction Syndrome in the Renal Intensive Care Unit: A Retrospective Single‐Center Study

Immunity, Inflammation and Disease, Volume 13, Issue 2, February 2025.
1. Patients with multiple organ dysfunction syndrome(MODS) are critically ill with high mortality in the renal intensive care unit (ICU). 2. Patients with persistent lymphocytopenia are more likely to be treated with mechanical ventilation, high dose vasoactive drugs, to be pathogen‐positive and at high risk of death, especially those with severe ...
Xiang Xue, Shuhua Zhu, Shutian Xu, Yuchao Zhou, Yang Wang, Lixuan Lou, Shijun Li   +6 more
wiley   +1 more source

Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia

Emerging Infectious Diseases, 2004
Pneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly Pneumocystis carinii) continues to cause illness and death in HIV-infected patients.
Charles Ben Beard, Patricia Roux, Gilles Nevez, Philippe M. Hauser, Joseph A. Kovacs, Thomas R. Unnasch, Bettina Lundgren   +6 more
doaj   +1 more source