Results 31 to 40 of about 10,212 (176)

Efficacy of upadacitinib induction for pediatric inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Objectives Upadacitinib, a second‐generation Janus kinase (JAK) inhibitor, is approved for moderate to severe Crohn's disease (CD) and ulcerative colitis (UC) in adults. Its efficacy in pediatric patients remains unclear, though early reports suggest benefits in refractory inflammatory bowel disease (IBD).
Evan Greenhall, Nina Gautam, Paula Prieto‐Jimenez, Elizabeth Hilow, Ashish Patel, Brad Pasternak   +5 more
wiley   +1 more source

Newly formed cystic lesions for the development of pneumomediastinum in Pneumocystis jirovecii pneumonia

BMC Infectious Diseases, 2009
Background Pneumocystis jirovecii, formerly named Pneumocystis carinii, is one of the most common opportunistic infections in human immunodeficiency virus (HIV)-infected patients.
Yoon Sung, Kwon Yong, Kim Dong-Min, Cho Ju-Yeon, Lee Seung   +4 more
doaj   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

The Role of Belatacept‐Use and Senescence on Infectious and Mortality Complications After Kidney Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam, Abdinoor Abdi, Wyatt Tarter, Ben Langworthy, Adam Bregman, Karam M. Obeid   +5 more
wiley   +1 more source

Detection of Pneumocystis jirovecii in Hospitalized Children Less Than 3 Years of Age

Journal of Fungi, 2021
Few data are available in the literature regarding Pneumocystis jirovecii infection in children under 3 years old. This retrospective cohort study aimed to describe medically relevant information among them.
Estelle Menu, Jean-Sélim Driouich, Léa Luciani, Aurélie Morand, Stéphane Ranque, Coralie L’Ollivier   +5 more
doaj   +1 more source

An Unusual Case Presentation on Docetaxel Induced Lung Injury

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Docetaxel can rarely cause acute interstitial lung injury early in therapy. New‐onset cough, fever, or dyspnea after chemotherapy should prompt immediate evaluation, exclusion of infection, and high‐resolution CT imaging. Early drug withdrawal and timely corticosteroid therapy can result in rapid clinical recovery and prevent serious morbidity.
Soorej Balan Kaliyath, S. Pavani, Arup Kumar Misra, A. Kesav Ramgopal, S. Yugandhar, Sushil Sharma, L. V. Simhachalam Kutikuppala, Golla Varshitha   +7 more
wiley   +1 more source

Amiodarone‐Induced Pulmonary Toxicity With Confirmed Elevated Plasma Mono‐Desethyl‐Amiodarone Levels

Respirology Case Reports, Volume 14, Issue 4, April 2026.
We report a case of pulmonary toxicity that developed 10 months after the initiation of amiodarone. The serum mono‐desethyl‐amiodarone concentration was elevated despite the relatively low cumulative amiodarone dose. ABSTRACT Amiodarone hydrochloride is an effective antiarrhythmic drug that can cause serious adverse effects, including amiodarone ...
Munechika Hara, Miki Kato, Fumika Sugiyama, Ryo Ichikawa, Tsutomu Hachiya   +4 more
wiley   +1 more source

Late presentation of Pneumocystis jirovecii pneumonia after renal transplant: A case report

Medical Mycology Case Reports, 2018
The highest risk of opportunistic infections is from 1 to 6 months post-transplant. We report a rare case of Pneumocystis jirovecii pneumonia in a renal transplant recipient only on maintenance immunosuppression eleven years after transplant without ...
Prithiv Prasad, Kevin Bryan Lo, Pradhum Ram   +2 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples

Journal of Fungi, 2020
Pneumocystis pneumonia (PcP) is a disease produced by the opportunistic infection of the fungus Pneumocystis jirovecii. As delayed or unsuitable treatments increase the risk of mortality, the development of rapid and accurate diagnostic tools for PcP are
Luis Pla, Anna Aviñó, Ramón Eritja, Alba Ruiz-Gaitán, Javier Pemán, Vicente Friaza, Enrique J. Calderón, Elena Aznar, Ramón Martínez-Máñez, Sara Santiago-Felipe   +9 more
doaj   +1 more source