Results 51 to 60 of about 27,058 (217)

Coexistência de infeções oportunistas pulmonares num doente com infeção por vírus da imunodeficiência humana e uma forma persistente de pneumonia por Pneumocystis jirovecii: caso clínico

Revista Portuguesa de Pneumologia, 2013
Resumo: Como é sabido, nos doentes com infeção por vírus da imunodeficiência humana (VIH) existe um alto risco de ocorrência de infeções oportunistas (IO), tais como as infeções por Pneumocystis jirovecii, um agente patogénico com distribuição mundial ...
D. Ponces Bento, F. Esteves, O. Matos, A.C. Miranda, F. Ventura, C. Araújo, K. Mansinho   +6 more
doaj   +1 more source

Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO)

Annals of Hematology, 2021
Hematologic and oncologic patients with chemo- or immunotherapy-related immunosuppression are at substantial risk for bacterial infections and Pneumocystis jirovecii pneumonia (PcP).
Annika Y. Classen, L. Henze, M. von Lilienfeld-Toal, G. Maschmeyer, M. Sandherr, Luisa Durán Graeff, N. Alakel, M. Christopeit, S. Krause, K. Mayer, S. Neumann, O. Cornely, O. Penack, F. Weissinger, H. Wolf, J. Vehreschild   +15 more
semanticscholar   +1 more source

Metagenomic Next-Generation Sequencing for the Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV-Infected Patients: A Retrospective Study

Infectious Disease and Therapy, 2021
This study aimed to evaluate the utility of metagenomic next-generation sequencing (mNGS) for the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in non-human immunodeficiency virus-infected patients. We conducted a retrospective study. A total of 60
Juan Jiang, L. Bai, Wei Yang, Wenzhong Peng, J. An, Yanhao Wu, P. Pan, Yuanyuan Li   +7 more
semanticscholar   +1 more source

Pneumocystis jirovecii colonization in chronic pulmonary disease

Parasite, 2011
Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization.
Gutiérrez S., Respaldiza N., Campano E., Martínez-Risquez M.T., Calderón E.J., De La Horra C.   +5 more
doaj   +1 more source

Characteristics and prognosis factors of Pneumocystis jirovecii pneumonia according to underlying disease: a retrospective multicentre study.

Chest
BACKGROUND Pneumocystis jirovecii pneumonia (PcP) remains associated with high rates of mortality and the impact of immunocompromising underlying disease on the clinical presentation, severity and mortality of PcP has not been adequately evaluated ...
Romain Lécuyer, N. Issa, Fabrice Camou, R. Lavergne, F. Gabriel, F. Morio, E. Canet, François Raffi, D. Boutoille, Anne Cady, M. Gousseff, Y. Crabol, Antoine Néel, B. Tessoulin, B. Gaborit   +14 more
semanticscholar   +1 more source

Diagnostic Value of Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing in Pneumocystis jirovecii Pneumonia in Non-HIV Immunosuppressed Patients

Frontiers in Cellular and Infection Microbiology, 2022
Introduction This study aims to assess the value of metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) in the diagnosis of Pneumocystis jirovecii pneumonia (PJP) and its mixed infection in non-human immunodeficiency ...
H. Sun, Feilong Wang, Ming Zhang, Xiao-yong Xu, Miaomiao Li, Wei Gao, Xiao-dong Wu, Huize Han, Qin Wang, Gehong Yao, Zheng Lou, Han Xia, Yi Shi, Qiang Li   +13 more
semanticscholar   +1 more source

Virtual Screening of Phytochemicals to Novel Target (HAT) Rtt109 in Pneumocystis Jirovecii using Bioinformatics Tools [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Pneumocystis jirovecii is a fungus that causes Pneumocystis pneumonia in HIV and other immunosuppressed patients. Treatment of Pneumocystis pneumonia with the currently available antifungals is challenging and associated with ...
Ramya Sugumar, Abhinand Ponneri Adithavarman, Anusha Dakshinamoorthi, Darling Chellathai David, Padmavathi Kannan Ragunath   +4 more
doaj   +1 more source

Alterations of lung microbiota in lung transplant recipients with pneumocystis jirovecii pneumonia

Respiratory Research
Background Increasing evidence revealed that lung microbiota dysbiosis was associated with pulmonary infection in lung transplant recipients (LTRs). Pneumocystis jirovecii ( P. jirovecii ) is an opportunistic fungal pathogen that frequently causes lethal
Q. Lian, Xiuling Song, Juhua Yang, Lulin Wang, Peihang Xu, Xiaohua Wang, Xin Xu, Bin Yang, Jianxing He, Chun-hua Ju   +9 more
semanticscholar   +1 more source

Clinical Performance of BAL Metagenomic Next-Generation Sequence and Serum (1,3)-β-D-Glucan for Differential Diagnosis of Pneumocystis jirovecii Pneumonia and Pneumocystis jirovecii Colonisation

Frontiers in Cellular and Infection Microbiology, 2021
Background Differentiating Pneumocystis jirovecii infection from colonisation is crucial for appropriate therapy administration. In this study, we evaluated the performance of bronchoalveolar lavage fluid (BAL) metagenomic next-generation sequencing ...
Li Liu, Ming Yuan, Yi Shi, X. Su
semanticscholar   +1 more source

A Randomized Phase II Study of Subcutaneous Mosunetuzumab in Combination With Polatuzumab Vedotin Compared With Rituximab Plus Polatuzumab Vedotin in Patients With Relapsed or Refractory Large B‐Cell Lymphoma

American Journal of Hematology, EarlyView.
ABSTRACT Mosunetuzumab plus polatuzumab vedotin has shown promising activity versus rituximab plus polatuzumab vedotin (R‐Pola) in patients with relapsed/refractory (R/R) large B‐cell lymphoma (LBCL; NCT03671018). We present results from the Phase II randomized cohort, evaluating subcutaneous mosunetuzumab plus polatuzumab vedotin (Mosun‐Pola), with ...
Julio C. Chavez, Mariana Bastos‐Oreiro, Catherine Diefenbach, Izidore S. Lossos, Nirav Shah, Sarit Assouline, Adam J. Olszewski, Seema Naik, Nilanjan Ghosh, Song Pham, Michael C. Wei, Connie Batlevi, Iris To, Wahib Ead, Sneha Makadia, Elicia Penuel, Jing Jing, Lihua E. Budde   +17 more
wiley   +1 more source