Results 51 to 60 of about 176,903 (205)

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

Internal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley, Philip George, Gemma Reynolds, Adam Stewart, Hang Quach, Nicole O'Leary, Zoe McQuilten, Andrea S. Henden, Lynette Chee, Chan Y. Cheah, Olivia Bupha‐Intr, Emily Blyth, Ben Teh, Monica Slavin, Michael Dickinson, Robert Weinkove   +15 more
wiley   +1 more source

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

Transplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal, Yong K. Kwon, Pamela L. Valentino, Jodi M. Smith, Patrick J. Healey, Zheyi Teoh   +5 more
wiley   +1 more source

Survey of the Transcription Factor Responses of Mouse Lung Alveolar Macrophages to Pneumocystis murina

Pathogens, 2021
Pneumocystis jirovecii is a fungal pathogen that can cause life-threatening infections in individuals who are immunocompromised. Acquired via inhalation, upon entering the respiratory tract, the fungi first encounter innate immune cells such as alveolar ...
Theodore J. Kottom, Kyle Schaefbauer, Eva M. Carmona, Andrew H. Limper   +3 more
doaj   +1 more source

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples

Journal of Fungi, 2020
Pneumocystis pneumonia (PcP) is a disease produced by the opportunistic infection of the fungus Pneumocystis jirovecii. As delayed or unsuitable treatments increase the risk of mortality, the development of rapid and accurate diagnostic tools for PcP are
Luis Pla, Anna Aviñó, Ramón Eritja, Alba Ruiz-Gaitán, Javier Pemán, Vicente Friaza, Enrique J. Calderón, Elena Aznar, Ramón Martínez-Máñez, Sara Santiago-Felipe   +9 more
doaj   +1 more source

Necrotizing Granulomatous Pneumocystis Infection Presenting as a Solitary Pulmonary Nodule: A Case Report and Review of the Literature

Case Reports in Pulmonology, 2022
Pneumocystis jirovecii is an opportunistic fungus that is classically associated with pneumonia in immunocompromised patients, particularly those with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS). However, this infection
Mansur Assaad, Mohamed Swalih, Apurwa Karki   +2 more
doaj   +1 more source

Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

European Journal of Haematology, Volume 117, Issue 5, Page 1258-1264, November 2026.
ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang, Rong Xiao, Xiaobing Huang, Yi Xiao   +3 more
wiley   +1 more source

Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients [PDF]

, 2003
Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Denis, CM, Wakefield, AE, Ambrose, HE, Lindley, AR, Miller, RF   +4 more
core  

pneumonia in a healthy immunocompetent patient: A case report and literature review

SAGE Open Medical Case Reports
Pneumocystis jirovecii pneumonia, typically an opportunistic infection, is commonly associated with risk factors such as low CD4+ lymphocyte count, underlying malignancies, organ transplantation, or immunosuppressive medications.
Houda Rouis, Chirine Moussa, Yoldez Houcine, Ines Zendah, Hamida Kwas, Habib Ghedira, Sonia Maâlej   +6 more
doaj   +1 more source

Pneumocystis jirovecii

, 2017
In humans, Pneumocystis pneumonia is caused by a yeast-like fungus Pneumocystis jirovecii. Originally called P. carinii, this organism was thought to be a protozoan; however, the discovery of chitin, β‎-1,3-glucan, and ergosterol in the cell wall ...
Stuart Flanagan
core   +1 more source