Results 71 to 80 of about 176,903 (205)

All‐Oral PI3Kδ and HDAC Inhibition with Parsaclisib Plus Chidamide and Step‐Down Maintenance in Relapsed or Refractory Peripheral T‐Cell Lymphoma: A Phase Ib Trial

MedComm, Volume 7, Issue 10, October 2026.
ABSTRACT Single‐agent targeted therapies for relapsed or refractory peripheral T‐cell lymphoma (R/R peripheral T‐cell lymphoma [PTCL]) produce modest, short‐lived responses, underscoring the need for tolerable, chemotherapy‐free combinations. In an open‐label, single‐arm Phase Ib trial at two tertiary hospitals, we evaluated parsaclisib plus chidamide ...
Xufeng Luo, Zheng Yan, Wei Fang, Hanchi Duan, Qiuyu Zhang, Haiying Wang, Shuna Yao, Jiuyang Zhang, Yiping Jin, Wenyong Li, Xiaolu Teng, Lina Zhang, Lijie Liang, Quande Lin, Ping Wang, Haoran Si, Jinxin Miao, Wenping Zhou, Zhihua Yao, You‐Wen He, Qingxin Xia, Yanyan Liu   +21 more
wiley   +1 more source

Additional file 1: of Impact of Pneumocystis jirovecii pneumonia on kidney transplant outcome

, 2019
Table S1. Information on the patients who had graft loss after the occurrence of Pneumocystis jirovecii pneumonia. Table S2. Information on the patients who died after the diagnosis of Pneumocystis jirovecii pneumonia.
Hajeong Lee (286887), Seung Han (3447431), Yon Kim (3409292), Ahram Han (2938878), Ji Kim (3527534), Jongwon Ha (230912)   +5 more
core   +1 more source

Ventilator-associated pneumonia after elective cardiac surgery caused by Pneumocystis jirovecii [PDF]

, 2014
Ventilator-associated pneumonia is a severe complication among patients undergoing cardiac surgery. Although hospital-acquired bacterial pathogens, often multidrug resistant, are the most frequent cause, non-bacterial atypical and opportunistic agents ...
Zamorano, Aníbal, Miller, Robert F., Silva, Francisco, Cifuentes, Marcela, Vargas Munita, Sergio, Tobar, Eduardo   +5 more
core   +3 more sources

Bruton's Tyrosine Kinase Inhibitors: Mechanisms, Efficacy, Toxicities and Applications for the Treatment of Human Diseases

MedComm, Volume 7, Issue 10, October 2026.
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley   +1 more source

Pneumocystis jirovecii infection in patients with acute interstitial pneumonia

, 2020
[ES] Objetivo: La neumonía intersticial aguda (NIA) es una enfermedad grave de etiología desconocida. Pneumocystis jirovecii es un hongo oportunista atípico capaz de colonizar pacientes con enfermedad pulmonar crónica e inducir la activación de los ...
Horra, Carmen de la, Martínez-Risquez M. T., Medrano, Francisco Javier, Friaza Patiño, Vicente, Calderón, Enrique J., Martín-Juan, José   +5 more
core   +1 more source

Mixed Invasive Aspergillus–Mucorales Pulmonary Coinfection in a Diabetic Patient: An Uncommon Dual Fungal Pneumonia and Literature Review

Respirology Case Reports, Volume 14, Issue 10, October 2026.
Our case describes a rare lung co‐infection caused by Aspergillus and Mucorales in a 61‐year‐old man with uncontrolled diabetes and chronic kidney disease. The diagnosis was made by BAL PCR and biopsy. Despite antifungal treatment, the patient worsened and died.
Vinay Venugopal, Saurabh Karmakar, Abdul Raouf Wani, Akshita Gupta, Gaurav Kumar Singh, Vijay Kumar, Shubhendu Mishra, Alpana Srivastava   +7 more
wiley   +1 more source

Bronchiectasis as the Sentinel Manifestation of ANCA‐Associated Vasculitis: A Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 10, October 2026.
A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim, Celine Vartany, Siddhanth Hegde, Kristie Lau, Lynette Tatosyan, Brannen Liang   +5 more
wiley   +1 more source

Pneumocystis jirovecii pneumonia: a case report

Journal of Medical Case Reports
Abstract Introduction and importance Pneumocystis jirovecii (PJP) pneumonia is a serious life-threatening condition in immunocompromised individuals and is often associated with human immunodeficiency virus (HIV) + patients.
Jacqueline Gri, Varun Jain
openaire   +3 more sources

Pneumocystis jiroveci Dihydropteroate Synthase Genotypes in Immunocompetent Infants and Immunosuppressed Adults, Amiens, France

Emerging Infectious Diseases, 2004
To date, investigations of Pneumocystis jiroveci circulation in the human reservoir through the dihydropteroate synthase (DHPS) locus analysis have only been conducted by examining P.
Anne Totet, Sophie Latouche, Philippe Lacube, Jean-Claude Pautard, Vincent Jounieaux, Christian Raccurt, Patricia Roux, Gilles Nevez   +7 more
doaj   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, Volume 13, Issue 54, 28 September 2026.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source