Results 91 to 100 of about 381,122 (317)
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon +4 more
wiley +1 more source
Molecular Respiratory Pathogen Panels in Lung Transplantation
ABSTRACT Molecular respiratory pathogen panels are an innovative tool for the rapid detection of respiratory pathogens and antimicrobial resistance genes, offering the potential to improve diagnostic accuracy and guide timely antimicrobial therapy.
Andrea Lombardi
wiley +1 more source
Stewardship of Molecular Diagnostics in Transplant Viral Infections
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden +3 more
wiley +1 more source
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam +5 more
wiley +1 more source
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients
Chronic granulomatous disease is a rare inborn error of immunity characterized by the deficient production of reactive oxygen species in phagocytes, which are used in pathogen elimination. Affected individuals become susceptible to severe infections.
Leonardo Martinello da Rosa +4 more
wiley +1 more source
Peripartum infections and associated maternal mortality in rural Malawi [PDF]
Article approval pendingTo assess associations between maternal mortality and severe morbidity and human immunodeficiency virus (HIV) infection, uptake of antiretroviral therapy, obstetric infections, and nonobstetric infections in a rural Malawian ...
Ahmad +23 more
core +3 more sources
Background In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation.
Shimizu Yasuo +6 more
doaj +1 more source
Risk Factors for Breakthrough Pneumocystis carinii Pneumonia on Aerosol Pentamidine Prophylaxis
OBJECTIVE: To identify baseline characteristics of human immunodeficiency virus (HIV)-infected individuals on aerosol pentamidine for Pneumocystis carinii prophylaxis that are predictive of subsequent breakthrough Pneumocystis carinii pneumonia (PCP).
RA McIvor +4 more
doaj +1 more source
Seasonal dynamics of Pneumocystis carinii in the field vole, Microtus agrestis, and in the common shrew, Sorex araneus, in Finland [PDF]
Seasonal dynamics of Pneumocystis carinii in the field vole, Microtus agrestis, and in the common shrew, Sorex araneus, were investigated in southern and central Finland by microscopical examination of methenamine silver-stained tissue sections.
Henttonen, H. +3 more
core +1 more source

