Results 191 to 199 of about 7,584 (199)

Immunodetection of pneumolysin in human urine by ELISA

Journal of Microbiological Methods, 2003
An ELISA test has been employed for the detection of pneumolysin (PLY) in urine from 14 pneumococcal pneumonia patients and from 11 healthy adult volunteers. The urines of all the 11 healthy adult volunteers developed signals around the mean of the blanks, whereas all the pneumococcal pneumonia patient urines rendered signals at least five times this ...
María Dolores, Cima-Cabal, Francisco J, Méndez, Fernando, Vázquez, Carlos, Aranaz, Javier, Rodríguez-Alvarez, José María, García-García, Ana, Fleites, Jaime, Martínez González-Río, Luis, Molinos, Dolores, de Miguel, Juan R, de los Toyos   +10 more
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Pneumococcal Neuraminidases Increase Platelet Killing by Pneumolysin

Thrombosis and Haemostasis
Background Platelets prevent extravasation of capillary fluids into the pulmonary interstitial tissue by sealing gaps in inflamed endothelium. This reduces respiratory distress associated with pneumonia. Streptococcus pneumoniae is the leading cause of severe community-acquired pneumonia.
Kristin J. Fritsch, Laura Krüger, Stefan Handtke, Thomas P. Kohler, Arina Ozhiganova, Kristin Jahn, Jan Wesche, Andreas Greinacher, Sven Hammerschmidt   +8 more
openaire   +2 more sources

Production of pneumolysin, a pneumococcal toxin, in Bacillus subtilis

Gene, 1989
We have expressed the pneumolysin gene of Streptococcus pneumoniae in Bacillus subtilis, both from its own promoter and as a fusion protein. The level of expression of pneumolysin from its own promoter was low. The protein produced was hemolytically active. A higher level of expression (about 10 micrograms/ml of culture) was achieved when either one of
S, Taira, E, Jalonen, J C, Paton, M, Sarvas, K, Runeberg-Nyman   +4 more
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Pneumolysin and Other Virulence Proteins

2014
Streptococcus pneumoniae (the pneumococcus) makes a range of molecules that can be considered virulence factors. The organism also makes a range of protein virulence factors, including surface proteins (choline-binding proteins, LPXTG-anchored proteins, and lipoproteins) as well as a range of enzymes (superoxide dismutase, NADH oxidase, zinc ...
openaire   +1 more source

Analysis of Immunobiological Properties of Recombinant Streptococcus pneumoniae Pneumolysin

Bulletin of Experimental Biology and Medicine
We compared the immunogenicity of recombinant S. pneumoniae pneumolysin (rPly) when administered with and without Al(OH)3 adjuvant, and evaluated the protective properties of recombinant protein in the active defense experiment. It was shown that double immunization with rPly+Al(OH)3 increases the levels of IgG antibodies in comparison with the control
D S, Vorobyev, E S, Petukhova, Yu V, Volokh, I B, Semenova   +3 more
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Antibodies protect platelet damage by pneumolysin

Hämostaseologie, 2021
S Handtke, K Jahn, R Palankar, TP Kohler, J Wesche, S Hammerschmidt, A Greinacher   +6 more
openaire   +1 more source

Pneumolysin

2015
Daniel R. Neill, Timothy J. Mitchell, Aras Kadioglu   +2 more
openaire   +1 more source

Pneumolysin and antipneumolysin.

Antimicrobial agents and chemotherapy, 1969
W D, Sutliff, A, Zoffuto
openaire   +1 more source

Funktionelle Charakterisierung des cholesterolabhängigen Cytolysins Pneumolysin

2014
openaire   +1 more source