Results 121 to 130 of about 304,306 (307)
The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 166-171, February 2023., 2023 Abstract ASPECT‐NP, a phase 3 trial of ceftolozane/tazobactam in hospital‐acquired/ventilator‐associated bacterial pneumonia (HABP/VABP), excluded patients with end‐stage renal disease (ESRD). A modeling/simulation approach was undertaken to inform optimal dosing in this population, using previously developed ceftolozane and tazobactam population ...
Hwa‐Ping Feng +7 more
wiley +1 more source
Predicting effects of structural stress in a genome-reduced model bacterial metabolism [PDF]
arXiv, 2012 We studied in silico effects of structural stress in Mycoplasma pneumoniae, a genome-reduced model bacterial organism, by tracking the damage propagating on its metabolic network after a deleterious perturbation. First, we analyzed failure cascades spreading from individual reactions and pairs of reactions and compared the results to those in ...
arxiv
Narrative review of primary care point-of-care testing (POCT) and antibacterial use in respiratory tract infection (RTI) [PDF]
, 2015 Antimicrobial resistance is a global problem and is being addressed through national strategies to improve diagnostics, develop new antimicrobials and promote antimicrobial stewardship. A narrative review of the literature was undertaken to ascertain the
Butler, Christopher +7 more
core +1 more source
Establishment of rat model for aspiration pneumonia and potential mechanisms
Animal Models and Experimental Medicine, EarlyView.Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu +7 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska +2 more
wiley +1 more source
Chronic steroid use: An overlooked impact on patients with inflammatory bowel disease
JGH Open, Volume 6, Issue 12, Page 910-914, December 2022., 2022 Steroids have long been used in inducing remission of inflammatory bowel disease (IBD), but there is controversy about whether IBD patients should be on chronic steroids for maintenance therapy. In this retrospective study, we aim to identify the complications of chronic steroid use in patients with IBD.
Kristen L Farraj +7 more
wiley +1 more source
Pneumonija kod bolesnika sa imunskim deficitom [PDF]
Vojnosanitetski Pregled, 2002 Marinković Olivera, Aćimović Slobodan
doaj +1 more source
MicroorganismsBackground: Pneumonia is one of the most common infectious diseases, mostly caused by viruses or bacteria. In response to bacteria or viruses which are different but which also are partly overlapping, innate and adaptive immune responses are induced ...
Katharina Konstanze Lilly Wagner +14 more
doaj +1 more source
Finding Covid-19 from Chest X-rays using Deep Learning on a Small Dataset [PDF]
arXiv, 2020 Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease.
arxiv
Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. [PDF]
, 2019 Community-acquired pneumonia (CAP) is a common cause of pediatric hospital admission. Empiric antibiotic therapy for hospitalized children with serious CAP now targets the most likely pathogen(s), including those that may demonstrate significant ...
Bradley, John S +8 more
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