Results 131 to 140 of about 1,205,800 (294)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Bacterial pneumonia

, 2020
Henry Knipe, Calum Worsley, Ammar Haouimi   +2 more
  +4 more sources

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Rhabdomyolysis and bacterial pneumonia

Respiratory Medicine, 1998
Byrd, R P., Roy, T M.
openaire   +3 more sources

Clinical Evaluation of the Effectiveness of Digital Peroral Cholangioscopy‐Guided Lithotripsy for Difficult Bile Duct Stones

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Aims Peroral cholangioscopy‐guided lithotripsy (POCS‐L) has emerged as a treatment option for difficult bile duct stones (DBDSs), but detailed evidence remains limited. This study evaluated its effectiveness, safety, and risk factors for adverse events (AEs).
Hirohito Minami, Shuntaro Mukai, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Kazumasa Nagai, Hiroyuki Kojima, Noriyuki Hirakawa, Kyoko Asano, Takao Itoi   +9 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

The 5R's of large language model‐assisted diagnosis: A practical framework for hospitalists

Journal of Hospital Medicine, EarlyView.
Abstract Diagnostic error remains a major patient safety challenge in hospital medicine. Large language models (LLMs) are increasingly used by clinicians to aid in diagnosis, yet most lack a structured approach for doing so safely and effectively. In this piece, we propose a practical, clinician‐centered framework for LLM‐assisted diagnosis.
Peter Barish, Andrew D. Auerbach, Sumant R. Ranji   +2 more
wiley   +1 more source

Factors associated with discharge on higher respiratory support for children with tracheostomy hospitalized with bacterial tracheostomy‐associated infections: A prospective, multicenter cohort study

Journal of Hospital Medicine, EarlyView.
Abstract We conducted a multicenter prospective cohort study to identify factors associated with discharge on higher respiratory support in children with tracheostomy hospitalized for bacterial tracheostomy‐associated infections (bTRAINs). We included children 0–21 years with tracheostomy hospitalized for bTRAIN at six freestanding children's hospitals
Krystal S. Jin, Naoko Kono, Jonathan D. Cogen, Sarah Hofman DeYoung, Catherine S. Forster, Andrea Hahn, Margaret Rush, John M. Morrison, Joanna E. Thomson, Sukhada V. Mairal, Michael N. Neely, Wendy J. Mack, Tamara D. Simon, Christopher J. Russell   +13 more
wiley   +1 more source