Results 151 to 160 of about 1,205,800 (294)

Efficacy of Lefamulin for Community-Acquired Bacterial Pneumonia (CABP) Patients: Pooled Analysis of the Lefamulin Evaluation Against Pneumonia (LEAP) 1, LEAP 2 and LEAP China Trials [PDF]

Shuo Liang,1 Yu-Hua Wen,1 Zhen-Hua Zhang,2 Yi Shi,3 Jin-Fu Xu1,4 1Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, People’s Republic of ...
Liang S, Xu JF, Zhang ZH, Wen YH, Shi Y
core  

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Bacterial Pneumonia in Horses: Insights from a 10-Year European Single-Centre Retrospective Study. [PDF]

Vet Sci
Stoeckle SD, Friedrich H, Jensen KC, Gehlen H.   +3 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Complete Blood Count-Derived Inflammatory Markers in Pediatric Lower Respiratory Tract Infection: A Narrative Review. [PDF]

Pathogens
Joan J, Chandra C, Wibisono CA, Gunawan HD, Chang V, Sumarpo A.   +5 more
europepmc   +1 more source

Diagnostic performance and clinical impact of the BioFire FilmArray Pneumonia Panel compared with conventional culture in hospitalized patients with pneumonia. [PDF]

PLoS One
Heo IR, Kim S.
europepmc   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Development and validation of a nomogram for differentiating bacterial from non-bacterial necrotizing pneumonia in children: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Zhang M, Zheng J, Dong H, Wang B, Xu Y.
europepmc   +1 more source

Respiratory profile of pediatric patients undergoing hematopoietic stem cell transplantation studied by oscillometry – A TRANSPIRE cohort

Pediatric Investigation, EarlyView.
These are results from a multi‐center collaboration between four large pediatric institutions, investigating baseline respiratory system function in a cohort of children undergoing hematopoietic stem cell transplantation. This manuscript proposes respiratory oscillometry as a novel way to prospectively follow lung function in these children.
Maureen B. Parenti, Julian Allen, Lisa R. Young, Heather Boas, Jason Freedman, Christopher Towe, Jane Koo, Kasiani Myers, Jason C. Woods, Adam Lane, Jonathan Gaffin, Wai Wong, Leslie Lehmann, Fernando Urrego, Gabriel Salinas Cisneros, Matthew F. Abts, K. Scott Baker, Manuel Silva‐Carmona, Erin Doherty, Paul D. Robinson, Margaret MacMillan, Stella M. Davies, Samuel B. Goldfarb   +22 more
wiley   +1 more source

Microbiological Profiles of Suspected Postoperative Pneumonia After Esophagectomy: A Focus on Gram-negative Pathogens. [PDF]

In Vivo
Matsubara T, Okamura H, Fujihara K, Nakajima K, Yasuda Y, Kawakami K, Yamada Y, Ishitobi K, Kaji S, Taniura T, Tanaka T, Yamamoto T, Hidaka M.   +12 more
europepmc   +1 more source