No temporal association between influenza outbreaks and invasive pneumococcal infections [PDF]
Objective: To assess whether the influenza peak in populations precedes the annual peak for invasive pneumococcal infections (IPI) in winter.Design: Ecological study.
Arenz, Stephan +3 more
core +1 more source
Since the early 2000s, pneumococcal conjugate vaccines (PCVs) have been shown to be effective in the prevention of pneumonia and invasive pneumococcal diseases.
I. Rivero-Calle +7 more
doaj +1 more source
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith +24 more
core +3 more sources
Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine. [PDF]
S. pneumoniae is a leading cause of meningitis morbidity and mortality in the African meningitis belt, but little is known of its contribution to the burden of pneumonia in the region.
Jennifer C Moïsi +8 more
doaj +1 more source
Estimating the burden of hospitalization for pneumococcal pneumonia in a general population aged 50 years or older and implications for vaccination strategies [PDF]
Streptococcus pneumoniae is a major cause of human infectious diseases worldwide. Despite this documented evidence, data on pneumococcal disease rates among general populations are scant because of the frequent lack of cultural identification.
AMODIO, Emanuele +5 more
core +1 more source
In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]
An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D. +8 more
core +1 more source
Pneumococcal serotype trends, surveillance and risk factors in UK adult pneumonia, 2013–18
Background Changes over the last 5 years (2013–18) in the serotypes implicated in adult pneumococcal pneumonia and the patient groups associated with vaccine-type disease are largely unknown.
H. Pick +17 more
semanticscholar +1 more source
Background: Pneumonia is one of the major causes of morbidity, mortality, and hospitalization. It is developed by a variety of organisms including Streptococcus pneumoniae and Legionella spp.
Tina Rabooki +4 more
doaj +1 more source
Pneumococcal pneumonia and the risk of stroke: a population-based follow-up study. [PDF]
BACKGROUND: To investigate the risk of developing stroke in patients hospitalized following a diagnosis of pneumococcal pneumonia. METHODS: The study cohorts comprised of patients hospitalized with a principal diagnosis of pneumococcal pneumonia (n ...
Li-Fu Chen +5 more
doaj +1 more source
A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A. +10 more
core +5 more sources

