Evaluation of acute and convalescent antibody concentration against pneumococcal capsular polysaccharides for the diagnosis of pneumococcal infection in children with community-acquired pneumonia [PDF]
We evaluated whether the quantification of IgG to pneumococcal capsular polysaccharides is an accurate diagnostic test for pneumococcal infection in children with pneumonia in Nepal.
Amatya, Puja+18 more
core +2 more sources
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith+24 more
core +3 more sources
The Significance of Subperiosteal Abscess Volume in Acute Mastoiditis
Both needle aspiration and I&D are safe methods to reduce the infective and inflammatory load of subperiosteal abscess due to acute mastoiditis and provide pus for culture. Higher volumes (~3 cm3 and more) should be managed initially with cortical mastoidectomy since the risk of no improvement following needle aspiration or I&D is higher.
Rani Abu‐Eta+5 more
wiley +1 more source
No temporal association between influenza outbreaks and invasive pneumococcal infections [PDF]
Objective: To assess whether the influenza peak in populations precedes the annual peak for invasive pneumococcal infections (IPI) in winter.Design: Ecological study.
Arenz, Stephan+3 more
core +1 more source
Early diagnosis of pneumococcal pneumonia [PDF]
Sir, Streptococcus pneumoniae is the commonest cause of community-acquired pneumonia (CAP) and benzylpenicillin is first choice for antimicrobial treatment of pneumococcal infections, unless resistance is a problem. Frequently, patients with CAP receive broader-spectrum antibiotics and macrolides because diagnosis of pneumococcal pneumonia on clinical ...
J. W. Van't Wout+3 more
openaire +3 more sources
Despite use of 7-valent pneumococcal conjugate vaccine, incidence of pleural effusion and empyema (pediatric complicated pneumococcal pneumonia [PCPP]) is reportedly increasing globally.
C. Silva-Costa+6 more
semanticscholar +1 more source
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen+7 more
wiley +1 more source
Pneumonia Detection in Chest X-Ray Images : Handling Class Imbalance [PDF]
People all over the globe are affected by pneumonia but deaths due to it are highest in Sub-Saharan Asia and South Asia. In recent years, the overall incidence and mortality rate of pneumonia regardless of the utilization of effective vaccines and compelling antibiotics has escalated.
arxiv
Bacteremic Pneumococcal Pneumonia in Children [PDF]
We carried out a nationwide retrospective study on bacteremic pneumococcal pneumonia diagnosed from 1985 to 1994 in Finland. The records of 85 children were reviewed for symptoms, signs, laboratory data, and response to antibiotic therapy. The chest radiographs were reevaluated.
Juhani Eskola+5 more
openaire +3 more sources
During spread of Streptococcus pneumoniae from the lung to the bloodstream, the pneumococcal pore‐forming toxin pneumolysin (PLY) disrupts apical junction complexes (AJCs) and triggers the transmigration of polymorphonuclear leukocytes (PMNs), which secrete tissue‐destructive neutrophil elastase.
Shuying Xu+4 more
wiley +1 more source