Results 81 to 90 of about 409,686 (231)

Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia

Frontiers in Immunology, 2018
Excessive activation of neutrophils results in the release of neutrophil elastase (NE), which leads to lung injury in severe pneumonia. Previously, we demonstrated a novel immune subversion mechanism involving microbial exploitation of this NE ability ...
H. Domon, K. Nagai, T. Maekawa, M. Oda, Daisuke Yonezawa, Wataru Takeda, Takumi Hiyoshi, Hikaru Tamura, M. Yamaguchi, S. Kawabata, Y. Terao   +10 more
semanticscholar   +1 more source

Cardio–Renal Diseases Are Independent Risk Factors of Severe Human Metapneumovirus Infection Among Patients Without Chronic Airway Diseases

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Wang Chun Kwok, Isaac Sze Him Leung, Chun Ka Emmanuel Wong, James Chung Man Ho, David Chi Leung Lam, Mary Sau Man Ip, Shuk Man Ngai, Kelvin Kai Wang To, Desmond Yat Hin Yap   +8 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Clagnan, E, Cocchio, Silvia, Del Zotto, S, Furlan, Patrizia, Gallo, T, Saia, Mario   +9 more
core   +1 more source

A Retrospective Study of Pneumococcal Pneumonia in Hospitalized Patients Aged ≥65 Years in Izumo, Japan: 2010 to 2014

International Journal of General Medicine, 2023
Megumi Hamaguchi,1 Yukari Tsubata,1 Ken Yoshihara,1 Mika Nakao,1 Yoshihiro Amano,1 Kazuhisa Nakashima,1 Takamasa Hotta,2 Tamio Okimoto,1 Shunichi Hamaguchi,3 Akihisa Sutani,4 Takeshi Isobe1 1Division of Medical Oncology and Respiratory Medicine ...
Hamaguchi M, Tsubata Y, Yoshihara K, Nakao M, Amano Y, Nakashima K, Hotta T, Okimoto T, Hamaguchi S, Sutani A, Isobe T   +10 more
doaj  

Pediatric Complicated Pneumonia Caused by Streptococcus pneumoniae Serotype 3 in 13-Valent Pneumococcal Conjugate Vaccinees, Portugal, 2010–2015

Emerging Infectious Diseases, 2018
Despite use of 7-valent pneumococcal conjugate vaccine, incidence of pleural effusion and empyema (pediatric complicated pneumococcal pneumonia [PCPP]) is reportedly increasing globally.
C. Silva-Costa, M. Brito, M. Pinho, A. Friães, S. Aguiar, M. Ramirez, J. Melo-Cristino   +6 more
semanticscholar   +1 more source

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

International Journal of Dermatology, Volume 65, Issue 2, Page 230-237, February 2026.
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín, Carolina Moreno, Ricardo Ruiz‐Villaverde, Esther Serra‐Baldrich, Irene Hernández‐Martín, Maria del Pilar Fortes   +5 more
wiley   +1 more source

Cross-sectional study on attitudes among general practitioners towards pneumococcal vaccination for middle-aged and elderly population in Hong Kong. [PDF]

PLoS ONE, 2013
OBJECTIVE: To study the attitudes among general practitioners towards pneumococcal vaccination for middle-aged (50-64) and elderly population (over 65) in Hong Kong and the factors affecting their decision to advise pneumococcal vaccination for those age
Lancelot W H Mui, Alvin Y S Chan, Albert Lee, John Lee   +3 more
doaj   +1 more source

The Burden of Respiratory Syncytial Virus in Children With Acute Otitis Media: A Systematic Review and Meta‐Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background Acute otitis media (AOM) affects over 709 million individuals globally each year, more than half of whom are children < 5 years. Respiratory syncytial virus (RSV) is a leading viral cause of pediatric respiratory illness. We aimed to estimate the burden of RSV in children < 5 years with AOM Methods We performed a systematic review ...
Sebastien Kenmoe, Marshall Dozier, Jingyi Liang, Ruth Jenkins, Harish Nair   +4 more
wiley   +1 more source

Attributable healthcare utilization and cost of pneumonia due to drug-resistant streptococcus pneumonia: a cost analysis [PDF]

, 2014
Background: The burden of disease due to S. pneumoniae (pneumococcus), particularly pneumonia, remains high despite the widespread use of vaccines. Drug resistant strains complicate clinical treatment and may increase costs.
Finkelstein, Jonathan A, Huang, Susan S, Moore, Matthew R, Ray, G Thomas, Reynolds, Courtney A   +4 more
core   +3 more sources

Pulmonary Alveolar Proteinosis Complicated by Invasive Streptococcus pneumoniae Infection Requiring Extracorporeal Membrane Oxygenation: A Case Report

Acute Medicine &Surgery, Volume 13, Issue 1, January/December 2026.
A rare case of autoimmune pulmonary alveolar proteinosis complicated by invasive Streptococcus pneumoniae infection was successfully managed with veno‐venous ECMO. ECMO enabled timely whole lung lavage during recovery from septic shock, which yielded atypical yellowish‐brown fluid likely reflecting infection and led to clinical improvement.
Utaho Mizusawa, Shinichiro Ohshimo, Kazuya Kikutani, Momoko Nakamura, Mitsuaki Nishikimi, Takeshi Namba, Yuki Masuka, Takahiro Inagawa, Nobuaki Shime   +8 more
wiley   +1 more source