Results 11 to 20 of about 402,090 (258)

Development and Evaluation of Rapid and Accurate CRISPR/Cas13-Based RNA Diagnostics for Pneumocystis jirovecii Pneumonia

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundPneumocystis jirovecii can result in a serious pulmonary infection, Pneumocystis jirovecii pneumonia, in immunocompetent hosts. The diagnosis of Pneumocystis jirovecii pneumonia has long been a major clinical concern, and there are limitations ...
Yangqing Zhan, Xiaoqing Gao, Shaoqiang Li, Yeqi Si, Yuanxiang Li, Xu Han, Wenjun Sun, Zhengtu Li, Feng Ye   +8 more
doaj   +2 more sources

Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG

Critical Care, 2023
Background Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patients admitted to intensive care ...
D. Giacobbe, S. Dettori, V. di Pilato, E. Asperges, L. Ball, E. Berti, O. Blennow, B. Bruzzone, L. Calvet, Federico Capra Marzani, A. Casabella, Sofia Choudaly, A. Dartevel, G. De Pascale, Gabriele Di Meco, Melissa Fallon, L. Galerneau, M. Gallego, M. Giacomini, Adolfo González Sáez, Luise Hänsel, G. Icardi, P. Koehler, K. Lagrou, T. Lahmer, P. Lewis White, L. Magnasco, A. Marchese, C. Marelli, M. Marín-Arriaza, I. Martín-Loeches, A. Mekontso-Dessap, M. Mikulska, A. Mularoni, A. Nordlander, J. Poissy, Giovanna Russelli, A. Signori, C. Tascini, Louis-Maxime Vaconsin, J. Vargas, A. Vena, J. Wauters, P. Pelosi, J. Timsit, M. Bassetti, Matteo Mario Chiara Denise Iole Filippo Sara Sofía Marice Cerchiaro Zaccarelli Robba Battaglini Brunetti Del, Matteo Cerchiaro, Mario Zaccarelli, C. Robba, D. Battaglini, I. Brunetti, F. Del Puente, Sara Mora, S. de la Villa, M. Valerio, Patricia Muñoz, G. Lombardi, Melania Cesarano, Veronica Gennenzi, P. Meersseman, G. Hermans, A. Wilmer, K. Razazi, G. Carteaux, N. de Prost, O. Cornely, D. Seidel, A. Alastruey‐Izquierdo, J. Garcia Borrega, C. Bonnal, É. de Montmollin, Julien Dessajan, M. Ceresini, F. Mojoli, A. Vola, C. Garnaud, E. Díaz, O. Gasch, E. Prina, S. Rasch, Miriam Dibos, Stefan Haschka   +82 more
semanticscholar   +1 more source

The Pathogenesis and Diagnosis of Pneumocystis jiroveci Pneumonia

Journal of Fungi, 2022
Pneumocystis jiroveci remains an important fungal pathogen in immunocompromised hosts. The environmental reservoir remains unknown. Pneumonia (PJP) results from airborne transmission, including in nosocomial clusters, or with reactivation after an ...
A. Apostolopoulou, J. Fishman
semanticscholar   +1 more source

Pneumocystis Pneumonia: Immunity, Vaccines, and Treatments

Pathogens, 2021
For individuals who are immunocompromised, the opportunistic fungal pathogen Pneumocystis jirovecii is capable of causing life-threatening pneumonia as the causative agent of Pneumocystis pneumonia (PCP). PCP remains an acquired immunodeficiency disease (
Aaron D. Gingerich, K. Norris, J. Mousa
semanticscholar   +1 more source

Diagnosing Pneumocystis jirovecii pneumonia: A review of current methods and novel approaches.

Medical Mycology, 2020
Pneumocystis jirovecii can cause life-threatening pneumonia in immunocompromised patients. Traditional diagnostic testing has relied on staining and direct visualization of the life-forms in bronchoalveolar lavage fluid.
M. Bateman, R. Oladele, J. Kolls
semanticscholar   +1 more source

Risk factors and prevention of Pneumocystis jirovecii pneumonia in patients with autoimmune and inflammatory diseases.

Chest, 2020
Patients with autoimmune and/or inflammatory diseases (AID) are prone to serious infectious complications such as Pneumocystis Jirovecii pneumonia (PJP). In non-HIV patients, the prognosis is poorer and diagnosis tests are of lower sensitivity. Given the
Amine Ghembaza, M. Vautier, P. Cacoub, Valérie Pourcher, D. Saadoun   +4 more
semanticscholar   +1 more source

Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia

Tuberculosis and Respiratory Diseases, 2020
In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia (PCP) is a wellk-nown opportunistic infection and its management has been established.
S. Tasaka
semanticscholar   +1 more source

Metagenomic Next-Generation Sequencing in Diagnosis of a Case of Pneumocystis jirovecii Pneumonia in a Kidney Transplant Recipient and Literature Review

Infection and Drug Resistance, 2020
Background Despite the increasing incidences of Pneumocystis jirovecii pneumonia (PCP) in renal transplant recipients, diagnosis of PCP remains challenging due to its nonspecific clinical presentation and the inadequate performance of conventional ...
Jie Chen, Ting He, Xiujun Li, Xue Wang, Li Peng, Liang Ma   +5 more
semanticscholar   +1 more source

Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia

Antimicrobial Agents and Chemotherapy, 2020
Antifungal prophylaxis is recommended to prevent invasive fungal disease caused by Candida spp., Aspergillus spp., and Pneumocystis jirovecii in patients at risk for opportunistic infections, such as allogeneic blood or marrow transplant recipients ...
L. Miesel, M. Cushion, A. Ashbaugh, Santiago R. Lopez, V. Ong   +4 more
semanticscholar   +1 more source

Pneumocystis Pneumonia: Pitfalls and Hindrances to Establishing a Reliable Animal Model

Journal of Fungi, 2022
Pneumocystis pneumonia is a severe lung infection that occurs primarily in largely immunocompromised patients. Few treatment options exist, and the mortality rate remains substantial. To develop new strategies in the fields of diagnosis and treatment, it
Adélaïde Chesnay, Christophe Paget, Nathalie Heuzé-Vourc’h, Thomas Baranek, Guillaume Desoubeaux   +4 more
doaj   +1 more source