Results 61 to 70 of about 1,362,134 (339)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Tissue-resident CD8+ T cells drive age-associated chronic lung sequelae after viral pneumonia

Science immunology, 2020
Age-associated TRM cell malfunction supports chronic lung inflammation and tissue fibrosis after respiratory viral infection. Role reversal for aged T cells Age-related changes to the adaptive immune system are associated with impaired host response and ...
N. Goplen, Yue Wu, Y. Son, Chaofan Li, Z. Wang, I. Cheon, Li Jiang, Bibo Zhu, K. Ayasoufi, E. Chini, Aaron J. Johnson, R. Vassallo, A. Limper, Nu Zhang, Jie Sun   +14 more
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

PROBLEMS OF ANTIBIOTIC THERAPY IN KOVID-ASSOCIATED HOSPITAL PNEUMONIA

Сучасні медичні технології, 2022
Introduction. The advent of the COVID-19 pandemic has posed challenges to healthcare professionals. The most common manifestation of a new variant of coronavirus disease is pneumonia, and therefore, the doctor is faced with the question of the diagnostic
O.A. Savchenko, S.L. Podsevahyna, A.V. Tkachenko, D.P. Myrnyi, Y.V. Katsiuba, A.I. Myrna   +5 more
doaj   +1 more source

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]

, 2017
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen, Angus, Bannasch, Barrs, Beatty, Bennett, Berryessa, Bexfield, Binns, Bongrand, Boothe, Bradley, Burns, Chalker, Chalker, Chan, Chandler, Confalonieri, Danish Small Animal Veterinary Association (SvHKS), Dear, Demetriou, Demko, Dossin, Drawz, Egberink, Ellis, Erles, German, Guardabassi, Hartmann, Helps, Henderson, Hollis, Hunter, Jameson, Johnson, Johnson, Johnson, Johnson, Johnson, Keil, Kogan, Kompare, Lee, Lees, Levy, Lionel, Litster, MacPhail, Maggs, Martino, McInnis, McKiernan, Meijvis, Melendez, Meyers, Mochizuki, Morley, Mulholland, Murphy, Owen, Papich, Parnham, Peeters, Pesavento, Priestnall, Priestnall, Proulx, Pui-Ying, Quimby, Quimby, Radhakrishnan, Renshaw, Rheinwald, Rheinwald, Rooney, Rozanski, Ruch-Galle, Ruch-Gallie, Ruch-Gallie, Schulz, Schwarz, Sparkes, Speakman, Speakman, Spindel, Stillion, Sturgess, Sykes, Tart, Trow, Tynan, Vanderkooi, Veir, Velineni, Viitanen, Waddell, Walker, Welsh, Westfall, Wong, Zhu   +101 more
core   +4 more sources

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Nature Communications, 2020
Emergence of SARS-CoV-2 causing COVID-19 has resulted in hundreds of thousands of deaths. In search for key targets of effective therapeutics, robust animal models mimicking COVID-19 in humans are urgently needed.
R. Boudewijns, H. Thibaut, S. Kaptein, Rong Li, V. Vergote, Laura Seldeslachts, J. Van Weyenbergh, Carolien de Keyzer, Lindsey Bervoets, Sapna Sharma, L. Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, T. Vercruysse, Xinyu Wang, D. Jochmans, E. Martens, K. Roose, D. De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, B. Vanmechelen, T. Wawina-Bokalanga, Leen Delang, J. Rocha-Pereira, Lotte Coelmont, Winston Chiu, P. Leyssen, E. Heylen, D. Schols, Lanjiao Wang, Lila Close, J. Matthijnssens, M. Van Ranst, V. Compernolle, G. Schramm, K. Van Laere, X. Saelens, N. Callewaert, G. Opdenakker, P. Maes, B. Weynand, C. Cawthorne, G. Vande Velde, Zhongde Wang, J. Neyts, K. Dallmeier   +50 more
semanticscholar   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Spectrum and Clinical Characteristics of Symptomatic and Asymptomatic Coronavirus Disease 2019 (COVID-19) With and Without Pneumonia

Frontiers in Medicine, 2021
Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Based on symptoms, COVID-19 cases can be classified as symptomatic or asymptomatic.
Huihui Zeng, Yiming Ma, Zhiguo Zhou, Wenlong Liu, Peng Huang, Mingyan Jiang, Qimi Liu, Ping Chen, Hong Luo, Yan Chen   +9 more
doaj   +1 more source

Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. [PDF]

, 2019
Community-acquired pneumonia (CAP) is a common cause of pediatric hospital admission. Empiric antibiotic therapy for hospitalized children with serious CAP now targets the most likely pathogen(s), including those that may demonstrate significant ...
Bradley, John S, Cannavino, Christopher R, Coufal, Nicole G, Farnaes, Lauge, Foley, Jennifer, Hong, David K, Pong, Alice, Ryan Loker, Kathleen, Wilke, Julianne   +8 more
core  

Bacterial Pneumonia in Dogs and Cats: An Update. [PDF]

, 2020
Bacterial pneumonia is a common clinical diagnosis in dogs but seems to occur less often in cats. Underlying causes include viral infection, aspiration injury, foreign body inhalation, and defects in clearance of respiratory secretions. Identification of
Dear, Jonathan D
core