Results 71 to 80 of about 215,510 (299)

Asthma and pneumonia viral species.

open access: yes, 2018
Asthma and pneumonia viral species.
Angel Miliar-Garcia (4857046)   +10 more
core   +1 more source

Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands. [PDF]

open access: yes, 2010
Micro (mi)RNAs are small non-coding RNAs that regulate the expression of their targets' messenger RNAs through both translational inhibition and regulation of target RNA stability.
Marcinowski, Lisa   +53 more
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine

open access: yesChinese Medicine, 2019
Nowadays, traditional Chinese medicines (TCMs) have been reported to provide reliable therapies for viral pneumonia, but the therapeutic mechanism remains unknown.
Lili Lin   +8 more
doaj   +1 more source

Outcomes of corticosteroid therapy in patients with viral community-acquired pneumonia [PDF]

open access: yes
Aim: The objective of this study was to assess the therapeutic effects of corticosteroids in adult patients hospitalized with viral community-acquired pneumonia.
Guzzardella, Amedeo   +5 more
core   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li   +11 more
wiley   +1 more source

Signs and symptoms indicative of community-acquired pneumonia in infants under six months

open access: yesBrazilian Journal of Infectious Diseases
OBJECTIVE: Evaluation of the clinical signs and symptoms predicting bacterial and viral pneumonia, in accordance with the Brazilian National Control Program for Acute Respiratory (ARI). METHODS: Observational prospective study.
Maria de Fátima Bazhuni Pombo March   +1 more
doaj   +1 more source

Pneumonia severity index in viral community acquired pneumonia in adults

open access: yes, 2019
Pneumonia severity index (PSI) is an important scoring system that can assess the severity of community acquired pneumonia and determine admission status.
Choong Won Lee (6429149)   +7 more
core   +1 more source

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

open access: yes, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Ebermann, L.   +37 more
core   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

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