Results 81 to 90 of about 6,138 (214)

CXCR3+ effector regulatory T cells associate with disease tolerance during lower respiratory pneumovirus infection

Immunology, Volume 172, Issue 3, Page 500-515, July 2024.
High dimensional flow cytometry reveals unique subsets of regulatory T cells essential for preventing severe lung damage in neonatal mice experiencing acute lower respiratory infection. Abstract Lifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower ...
Ismail Sebina, Sylvia Ngo, Ridwan B. Rashid, Mariah Alorro, Patricia Namubiru, Daniel Howard, Tufael Ahmed, Simon Phipps   +7 more
wiley   +1 more source

Breaking In: Human Metapneumovirus Fusion and Entry

Viruses, 2013
Human metapneumovirus (HMPV) is a leading cause of respiratory infection that causes upper airway and severe lower respiratory tract infections. HMPV infection is initiated by viral surface glycoproteins that attach to cellular receptors and mediate ...
John V. Williams, Reagan G. Cox
doaj   +1 more source

Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Veterinary Research, 2023
Bovine respiratory syncytial virus (BRSV) is a pathogenic pneumovirus and a major cause of acute respiratory infections in calves. Although different vaccines are available against BRSV, their efficiency remains limited, and no efficient and large-scale ...
Jenna Fix, Delphyne Descamps, Marie Galloux, Cécile Ferret, Edwige Bouguyon, Siamak Zohari, Katarina Näslund, Sara Hägglund, Ralf Altmeyer, Jean-François Valarcher, Sabine Riffault, Jean-François Eléouët   +11 more
doaj   +1 more source

A Randomized, Double‐Blind, Placebo‐Controlled, Phase 1 Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Single Vaccination of Ad26.RSV.preF‐Based Regimen in Japanese Adults Aged 60 Years and Older

Influenza and Other Respiratory Viruses, Volume 18, Issue 6, June 2024.
ABSTRACT Background Respiratory syncytial virus (RSV) is increasingly recognized as a significant cause of lower respiratory tract disease (LRTD) in older adults. The Ad26.RSV.preF/RSV preF protein vaccine demonstrated protective efficacy against RSV related LRTD in a Phase 2b study in the United States.
Takashi Eto, Yusuke Okubo, Atsushi Momose, Hiroshi Tamura, Richuan Zheng, Benoit Callendret, Arangassery Rosemary Bastian, Christy A. Comeaux   +7 more
wiley   +1 more source

Birth characteristics as predictors of respiratory syncytial virus hospitalisation in newborns to optimise immunisation schedule

Acta Paediatrica, Volume 113, Issue 5, Page 1087-1094, May 2024.
Abstract Aim To examine birth characteristics that influence infant respiratory syncytial virus (RSV) hospitalisation risk in order to identify risk factors for severe RSV infections. Methods Retrospective cohort study of 460 771 Sicilian children under 6 months old from January 2007 to December 2017.
Emanuele Amodio, Vincenzo Pisciotta, Dario Genovese, Giuseppe Vella, Maria Gabriella Verso, Mario Giuffrè, Francesco Vitale   +6 more
wiley   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Suppression subtractive hybridization coupled with microarray analysis to examine differential expression of genes in virus infected cells

Biological Procedures Online, 2004
High throughput detection of differential expression of genes is an efficient means of identifying genes and pathways that may play a role in biological systems under certain experimental conditions. There exist a variety of approaches that could be used
Munir Shirin, Singh Sushmita, Kaur Kuljeet, Kapur Vivek   +3 more
doaj   +1 more source

Seroprevalence and molecular characterisation of infectious bronchitis virus (IBV) in broiler farms in Sabah, Malaysia

Veterinary Medicine and Science, Volume 10, Issue 2, March 2024.
Abstract Background Infectious bronchitis virus (IBV) is classified as a highly contagious viral agent that causes acute respiratory, reproductive and renal system pathology in affected poultry farms. Molecular and serological investigations are crucial for the accurate diagnosis and management of IBV.
Md. Safiul Alam Bhuiyan, Subir Sarker, Zarina Amin, Kenneth Francis Rodrigues, Ag Muhammad Sagaf Abu Bakar, Suryani Saallah, Sharifudin Md. Shaarani, Shafiquzzaman Siddiquee   +7 more
wiley   +1 more source

Human metapneumovirus: understanding the molecular mechanisms and pathology of infection

Journal of Virology
Human metapneumovirus (HMPV) is a common and globally prevalent respiratory virus that can cause clinical symptoms ranging from mild respiratory illness to severe bronchiolitis and pneumonia, with substantial morbidity and mortality.
Chase J. Heim, Bernadette G. van den Hoogen, Rebecca E. Dutch   +2 more
doaj   +1 more source

Immune‐mediated polyarthritis and anterior uveitis secondary to zonisamide administration in a dog with refractory epilepsy

Veterinary Medicine and Science, Volume 10, Issue 2, March 2024.
A dog with refractory seizures was presumed to have developed immune‐mediated polyarthritis (IMPA) and anterior uveitis secondary to zonisamide administration. Symptoms began shortly after the initiation of zonisamide and completely resolved within 2 weeks of discontinuation. Diagnostics did not reveal any other causes.
Paula Baya, Saya Press, Stephanie Istvan, Kaila Rizzo   +3 more
wiley   +1 more source