Novel renewable immunosensors based on temperature-sensitive PNIPAAm bioconjugates
Biosensors and Bioelectronics, 2008A novel renewable immunosensor was created comprising a temperature-controlled surface composed of poly(n-isopropylacrylamide) (PNIPAAm)-antibody conjugates that could reversibly bind the antigen. Bovine serum albumin (BSA) and the corresponding antibody (anti-BSA) were chosen as a model antibody-antigen system to demonstrate the concept. The thermally
Ying, Liu +5 more
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Thermosensitive PNIPAAm cryogel with superfast and stable oscillatory properties
Chemical Communications, 2003Through copolymerization/crosslinking in dimethyl sulfoxide (DMSO) at temperature below the melting point of DMSO, we demonstrated a novel poly(N-isopropylacrylamide) (PNIPAAm) hydrogel with regularly oriented micromatrix; the superfast/stable oscillatory hydration-dehydration character of this hydrogel would find wide applications in biomedical field.
Xian-Zheng, Zhang, Chih-Chang, Chu
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Salt Sensitivity of the Thermoresponsive Behavior of PNIPAAm Brushes
Langmuir, 2018We report investigations on the salt sensitivity of the thermoresponsive behavior of PNIPAAm brushes applying the quartz crystal microbalance coupled with spectroscopic ellipsometry technique. This approach enables a detailed study of the optical and mechanical behavior of the polymer coatings.
Meike Koenig +7 more
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Characterization and cell material interactions of PEGylated PNIPAAM nanoparticles
Colloids and Surfaces B: Biointerfaces, 2010The aim of this study was to investigate the haemocompatibility of poly(N-isopropylacrylamide)-co-poly(ethylene glycol), PNIPAAM-PEG based nanoparticles and the influence of poly(ethylene glycol), PEG on the interactions of nanoparticles with cells.
Nany, Gulati +4 more
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Novel Biodegradable and Thermosensitive Dex‐AI/PNIPAAm Hydrogel
Macromolecular Bioscience, 2003AbstractThe dextran‐allyl isocyanate/poly(N‐isopropylacrylamide) (Dex‐AI/PNIPAAm) hydrogel was designed and prepared by copolymerization of the modified dextran with N‐isopropylacrylamide (NIPAAm). This novel Dex‐AI/PNIPAAm hydrogel is biodegradable and intelligent due to its biodegradable dextran linkage and thermosensitive PNIPAAm moiety.
Xian‐Zheng Zhang +3 more
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Protein Resistance of PNIPAAm Brushes: Application to Switchable Protein Adsorption
Langmuir, 2009Protein adsorption, as the primary process occurring when a foreign surface comes into contact with a biosystem, was studied on thin polymer brush films consisting of poly(N-isopropylacrylamide) (PNIPAAm) and poly(2-vinylpyridine) (P2VP). These films were prepared by the "grafting to" method. The protein resistance of stimuli responsive PNIPAAm-brushes
Sina, Burkert +7 more
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Mechanical and rheological behavior of pNIPAAM crosslinked macrohydrogel
Reactive and Functional Polymers, 2013In this study for the first time we investigate the most common reticulated N-isopropylacrylamide (pNIPAAM) macrohydrogel for both its mechanical response and shear rheological behavior in time and frequency domains. Hydrogels are characterized by water content volume and weight measurements, FT-IR spectroscopy, scanning electron microscopy and ...
Puleo G. L. +6 more
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Synthesis and Characterization of TZD Loaded PNIPAAm-b-PU-b-PNIPAAm Tri-Block Gold Nanopolymer
International Journal of Green Nanotechnology, 2012ABSTRACT Block copolymers have been used extensively in the synthesis of different types of nanoparticles. A novel ABA type PNIPAAm-b-PU-b-PNIPAAm tri-block nanopolymer has been synthesized via atom transfer radical polymerization (ATRP) technique using a tertiary bromo-terminated as a macro-initiator and was characterized by nuclear magnetic resonance
Prashant Singh +3 more
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Thermoresponsive “irreversible” property change of POSS-crosslinked PNIPAAm hydrogels
Polymer Chemistry, 2023Incorporation of a strongly hydrophobic component as a crosslinking point enables reversibility control of property change of thermoresponsive hydrogels.
Shohei Ida +7 more
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Cell growth and detachment from protein‐coated PNIPAAm‐based copolymers
Journal of Biomedical Materials Research Part A, 2007AbstractThe cultivation of cells requires the use of unfavorable proteolytic enzymes, which cause cell‐surface modification and also need considerable optimization. Recently, with the development of smart polymers, research has looked to using thermoresponsive polymers as cell culture substrates.
Martin T, Moran +4 more
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