Results 211 to 220 of about 5,147 (230)
Some of the next articles are maybe not open access.
Cancer Research, 2023
Eukaryotic cells have two separate genomes; nuclear chromosomal DNA and circular mitochondrial DNA. Mitochondrial DNA lacks introns, and encodes 2 rRNAs, 22 t-RNAs and 13 of the 90 proteins that constitute the mitochondrial respiratory chain.
G. Thomas +14 more
semanticscholar +1 more source
Eukaryotic cells have two separate genomes; nuclear chromosomal DNA and circular mitochondrial DNA. Mitochondrial DNA lacks introns, and encodes 2 rRNAs, 22 t-RNAs and 13 of the 90 proteins that constitute the mitochondrial respiratory chain.
G. Thomas +14 more
semanticscholar +1 more source
The FASEB Journal, 2022
Understanding the localization and regulatory activity of extra‐nuclear long non‐coding RNAs (lncRNAs) is especially critical in the context of the mitochondrion, which possesses a genome separate from the nucleus that dictates bioenergetic function and ...
Andrew D Taylor +9 more
semanticscholar +1 more source
Understanding the localization and regulatory activity of extra‐nuclear long non‐coding RNAs (lncRNAs) is especially critical in the context of the mitochondrion, which possesses a genome separate from the nucleus that dictates bioenergetic function and ...
Andrew D Taylor +9 more
semanticscholar +1 more source
RNase E biomolecular condensates stimulate PNPase activity
2022AbstractBacterial Ribonucleoprotein bodies (BR-bodies) play an essential role in organizing RNA degradation via liquid-liquid phase separation in the cytoplasm of bacteria. BR-bodies mediate multi-step mRNA decay through the concerted activity of the endoribonuclease RNase E coupled with the 3’-5’ exonuclease Polynucleotide Phosphorylase (PNPase).
Michael Collins +3 more
openaire +1 more source
Microbial Pathogenesis, 2013
The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella enterica serovar Typhimurium genes required for survival in an ex vivo swine stomach content assay.
S M D, Bearson +3 more
openaire +2 more sources
The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella enterica serovar Typhimurium genes required for survival in an ex vivo swine stomach content assay.
S M D, Bearson +3 more
openaire +2 more sources
Biochimie, 2014
Polynucleotide phosphorylase (PNPase) reversibly catalyzes RNA phosphorolysis and polymerization of nucleoside diphosphates. Its homotrimeric structure forms a central channel where RNA is accommodated. Each protomer core is formed by two paralogous RNase PH domains: PNPase1, whose function is largely unknown, hosts a conserved FFRR loop interacting ...
Carzaniga, T +8 more
openaire +3 more sources
Polynucleotide phosphorylase (PNPase) reversibly catalyzes RNA phosphorolysis and polymerization of nucleoside diphosphates. Its homotrimeric structure forms a central channel where RNA is accommodated. Each protomer core is formed by two paralogous RNase PH domains: PNPase1, whose function is largely unknown, hosts a conserved FFRR loop interacting ...
Carzaniga, T +8 more
openaire +3 more sources
Molecular Microbiology, 1996
Summary PNPase and RNase II are the key regulatory exo‐nucleases controlling mRNA decay in Escherichia coli The rnb transcripts were found to proceed through the terminator and PNPase was found to be involved in the 3’to 5’degradation of rnb mRNA. Analysis of these longer 3’termini revealed that they are located in UA‐rich regions. Comparison of single
R, Zilhão +3 more
openaire +2 more sources
Summary PNPase and RNase II are the key regulatory exo‐nucleases controlling mRNA decay in Escherichia coli The rnb transcripts were found to proceed through the terminator and PNPase was found to be involved in the 3’to 5’degradation of rnb mRNA. Analysis of these longer 3’termini revealed that they are located in UA‐rich regions. Comparison of single
R, Zilhão +3 more
openaire +2 more sources
Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci
Nucleic Acids Research, 2013Lukasz S Borowski +2 more
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