Results 71 to 80 of about 257,197 (291)

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Health care workers' perceptions of point-of-care testing in a low-income country-A qualitative study in Southwestern Uganda. [PDF]

PLoS ONE, 2017
BACKGROUND:Point-of-care (POC) tests have become increasingly available and more widely used in recent years. They have been of particular importance to low-income settings, enabling them with clinical capacities that had previously been limited.
Reza Rasti, Deborah Nanjebe, Jonas Karlström, Charles Muchunguzi, Juliet Mwanga-Amumpaire, Jesper Gantelius, Andreas Mårtensson, Lourdes Rivas, Francesc Galban, Philippa Reuterswärd, Helene Andersson Svahn, Helle M Alvesson, Yap Boum, Tobias Alfvén   +13 more
doaj   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene

Advanced Science, EarlyView.
A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain, Heiko Heilmann, Annabel Pohl, Celine Weber, Bernd Bufe, Alexey Tarasov   +5 more
wiley   +1 more source

Point-of-care testing for disasters: needs assessment, strategic planning, and future design. [PDF]

, 2009
Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions.
Bangs, Bulut, Cazacu, de la Hoz, Dighe, Diiulio, Ender, Farfel, Gerald J. Kost, Ginocchio, Grandjean, Grondhal, Hiransuthikul, Hurt, Ivers, Kazancioglu, Kost, Kost, Kost, Kost, Kost, Kristin N. Hale, Lam, Louie, Lupisan, Millie, MMWR, Nam K. Tran, Nicole L. Gentile, Nishiura, Pabbaraju, Qadri, Rajendran, Richard F. Louie, Schneider, Shaman, Shaman, Sinigalliano, T. Keith Brock, Tao, Thomas, Tyler K. Kitano, Uckay, Vernon, Vollaard   +44 more
core   +1 more source

Enhancing Chemical Stability and Molecular Selectivity of Porous Organic Cages via Core–Shell Polymer Coating

Advanced Science, EarlyView.
This study presents an interfacial method to fabricate POC@polymer core–shell nanostructures combining cage porosity with polymer robustness. Through chiral self‐assembly and non‐solvent‐induced surface polymerisation, uniform ∼20 nm polymer‐coated particles are produced.
Danyu Li, Yanling Huang, Huiyu Liu, Yuzhen Wen, Dongxu Wang, Tao Li, Shan Jiang   +6 more
wiley   +1 more source

WICK SYSTEM IN VARIOUS NUTRITION COMBINATIONS ON PAKCOY GROWTH AND YIELD

Jurnal Agrotek Tropika
This study aimed to examine the growth and yield of cabbage (Brassica rapa L.) plants grown in a hydroponic wick system using varying doses of AB Mix nutrients and Azolla liquid organic fertilizer (POC).
Rohmatin Agustina, Widya Oktaviani, Rahmad Jumadi   +2 more
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Fluvial organic carbon flux from an eroding peatland catchment, southern Pennines, UK [PDF]

, 2008
This study investigates for the first time the relative importance of dissolved organic carbon (DOC) and particulate organic carbon (POC) in the fluvial carbon flux from an actively eroding peatland catchment in the southern Pennines, UK.
Allott, T. E H, Daniels, S.M., Evans, M. G., Lord, D. R., Pawson, R. R.   +4 more
core   +2 more sources

From Droplet to Diagnosis: Spatio‐Temporal Pattern Recognition in Drying Biofluids

Advanced Intelligent Systems, EarlyView.
This article integrates machine learning (ML) with the spatio‐temporal evolution of biofluid droplets to reveal how drying and self‐assembly encode distinctive compositional fingerprints. By leveraging textural features and interpretable ML, it achieves robust classification of blood abnormalities with over 95% accuracy.
Anusuya Pal, Amalesh Gope, Miho Yanagisawa   +2 more
wiley   +1 more source